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Protein one-dimensional (1D) structures such as secondary structure and contact number provide intuitive pictures to understand how the native three-dimensional (3D) structure of a protein is encoded in the amino acid sequence. However, it…

Biomolecules · Quantitative Biology 2007-05-23 Akira R. Kinjo , Ken Nishikawa

The success of graphene for nanopore DNA sequencing has shown that it is possible to explore other potential single-atom and few-atom thick layers of elemental 2D materials beyond graphene (e.g., phosphorene and silicene). Using density…

Mesoscale and Nanoscale Physics · Physics 2021-12-15 Matthew B. Henry , Mukesh Tumbapo , Benjamin O. Tayo

Synthetic DNA can in principle be used for the archival storage of arbitrary data. Because errors are introduced during DNA synthesis, storage, and sequencing, an error-correcting code (ECC) is necessary for error-free recovery of the data.…

Quantitative Methods · Quantitative Biology 2018-12-05 William H. Press , John A. Hawkins

While accurate protein structure predictions are now available for nearly every observed protein sequence, predicted structures lack much of the functional context offered by experimental structure determination. We address this gap with…

Quantitative Methods · Quantitative Biology 2023-02-08 Nasim Abdollahi , Seyed Ali Madani Tonekaboni , Jay Huang , Bo Wang , Stephen MacKinnon

String barcoding is a recently introduced technique for genomic-based identification of microorganisms. In this paper we describe the engineering of highly scalable algorithms for robust string barcoding. Our methods enable distinguisher…

Data Structures and Algorithms · Computer Science 2016-08-31 Bhaskar DasGupta , Kishori M. Konwar , Ion I. Mandoiu , Alex A. Shvartsman

In this paper we have proposed a method that uses chaotic logistic mapping and DNA encoding to encrypt the image. A 32 bit ASCII private key is used to diffuse the image. The results demonstrated clearly show that encryption algorithm based…

Cryptography and Security · Computer Science 2020-03-17 Sakshi Patel , Bharath K P , Rajesh Kumar Muthu

Data compression has been widely applied in many data processing areas. Compression methods use variable-size codes with the shorter codes assigned to symbols or groups of symbols that appear in the data frequently. Fibonacci coding, as a…

Performance · Computer Science 2007-12-19 R. Baca , V. Snasel , J. Platos , M. Kratky , E. El-Qawasmeh

We consider binary systematic network codes and investigate their capability of decoding a source message either in full or in part. We carry out a probability analysis, derive closed-form expressions for the decoding probability and show…

Information Theory · Computer Science 2016-11-15 Andrew L. Jones , Ioannis Chatzigeorgiou , Andrea Tassi

The synthesis of DNA strands remains the most costly part of the DNA storage system. Thus, to make DNA storage system more practical, the time and materials used in the synthesis process have to be optimized. We consider the most common…

Information Theory · Computer Science 2023-05-15 Johan Chrisnata , Han Mao Kiah , Van Long Phuoc Pham

Two-dimensional (2D) materials have attracted extensive attention due to their unique characteristics and application potentials. Raman spectroscopy, as a rapid and non-destructive probe, exhibits distinct features and holds notable…

Applied Physics · Physics 2023-12-05 Yaping Qi , Dan Hu , Zhenping Wu , Ming Zheng , Guanghui Cheng , Yucheng Jiang , Yong P. Chen

Diffusion Magnetic Resonance Imaging (dMRI) is one of the most important contemporary non-invasive modalities for probing tissue structure at the microscopic scale. The majority of dMRI techniques employ standard single diffusion encoding…

Deep learning has been a groundbreaking technology in various fields as well as in communications systems. In spite of the notable advancements of deep neural network (DNN) based technologies in recent years, the high computational…

Information Theory · Computer Science 2018-08-08 Minhoe Kim , Woonsup Lee , Jungmin Yoon , Ohyun Jo

This paper describes a novel approach to synthesize molecular reactions to train a perceptron, i.e., a single-layered neural network, with sigmoidal activation function. The approach is based on fractional coding where a variable is…

Emerging Technologies · Computer Science 2020-04-01 Xingyi Liu , Keshab K. Parhi

In this paper we present a thorough analysis of non binary LDPC codes over the binary erasure channel. First, the decoding of non binary LDPC codes is investigated. The proposed algorithm performs on-the-fly decoding, i.e. it starts…

Information Theory · Computer Science 2008-10-27 Valentin Savin

Segmenting biomarkers in medical images is crucial for various biotech applications. Despite advances, Transformer and CNN based methods often struggle with variations in staining and morphology, limiting feature extraction. In medical…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Saad Wazir , Daeyoung Kim

Generative models have achieved impressive results in many domains including image and text generation. In the natural sciences, generative models have led to rapid progress in automated drug discovery. Many of the current methods focus on…

Machine Learning · Computer Science 2019-09-04 Jordan Hoffmann , Louis Maestrati , Yoshihide Sawada , Jian Tang , Jean Michel Sellier , Yoshua Bengio

Evolution is an extraordinary engine for enzymatic diversity, yet the chemistry it has explored remains a narrow slice of what DNA can encode. Deep generative models can design new proteins that bind ligands, but none have created enzymes…

Since the birth of computer and networks, fuelled by pervasive computing and ubiquitous connectivity, the amount of data stored and transmitted has exponentially grown through the years. Due to this demand, new solutions for storing data…

A prescription to calculate the minimum number of bits needed for binary strip detector readout is presented. This permits a systematic analysis of the readout efficiency relative to this theoretical minimum number of bits. Different level…

Instrumentation and Detectors · Physics 2015-06-17 Maurice Garcia-Sciveres , Xinkang Wang

DNA synthesis is considered as one of the most expensive components in current DNA storage systems. In this paper, focusing on a common synthesis machine, which generates multiple DNA strands in parallel following a fixed supersequence,we…

Information Theory · Computer Science 2025-05-13 Yajuan Liu , Tolga M. Duman
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