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Cells sense environmental signals and transmit information intracellularly through changes in the abundance of molecular components. Such molecular abundances can be measured in single cells and exhibit significant heterogeneity in clonal…

Quantitative Methods · Quantitative Biology 2024-09-27 Raymond Fan , Andreas Hilfinger

We quantify the influence of the topology of a transcriptional regulatory network on its ability to process environmental signals. By posing the problem in terms of information theory, we may do this without specifying the function…

Molecular Networks · Quantitative Biology 2015-06-26 Etay Ziv , Ilya Nemenman , Chris H. Wiggins

Electrical signals play the primary role in rapid communication among organs, tissues and cells in biosystems. We have analyzed and discussed three phenomena of electrical communication in biosystems, including direction-changing movement…

Biological Physics · Physics 2017-08-11 Jingjing Xu , Fan Yang , Danhong Han , Shengyong Xu

Sensor Networks produce a large amount of data. According to the needs this data requires to be processed, delivered and accessed. This processed data when made available with the physical device location, user preferences, time…

Networking and Internet Architecture · Computer Science 2013-09-04 Vijay Borges , Wilson Jeberson

Signal propagation in biochemical networks is characterized by the inherent randomness in gene expression and fluctuations of the environmental components, commonly known as intrinsic and extrinsic noise, respectively. We present a…

Molecular Networks · Quantitative Biology 2024-08-09 Mintu Nandi , Sudip Chattopadhyay , Somshubhro Bandyopadhyay , Suman K Banik

Correlations of ambient seismic or acoustic vibrations are now widely used to reconstruct the impulse response between two passive receivers as if a source was placed at one of them. This provides the opportunity to do imaging without a…

Other Condensed Matter · Physics 2009-11-13 Eric Larose , Arnaud Derode , Philippe Roux , Michel Campillo

Living cells can enhance their fitness by anticipating environmental change. We study how accurately linear signaling networks in cells can predict future signals. We find that maximal predictive power results from a combination of…

Molecular Networks · Quantitative Biology 2016-01-20 Nils B. Becker , Andrew Mugler , Pieter Rein ten Wolde

The passive estimation of impulse responses from ambient noise correlations arouses increasing interest in seismology, acoustics, optics and electromagnetism. Assuming the equipartition of the noise field, the cross-correlation function…

The manner in which signals propagate through dense granular systems in both space and time is not well understood. In order to learn more about this process, we carry out discrete element simulations of the system response to excitations…

Soft Condensed Matter · Physics 2008-05-15 L. Kondic , O. M. Dybenko , R. P. Behringer

Correlations in sensory neural networks have both extrinsic and intrinsic origins. Extrinsic or stimulus correlations arise from shared inputs to the network, and thus depend strongly on the stimulus ensemble. Intrinsic or noise…

Neurons and Cognition · Quantitative Biology 2018-11-05 Ulisse Ferrari , Stephane Deny , Matthew Chalk , Gasper Tkacik , Olivier Marre , Thierry Mora

Although continuous advances in theoretical modelling of Molecular Communications (MC) are observed, there is still an insuperable gap between theory and experimental testbeds, especially at the microscale. In this paper, the development of…

Noise is widely understood to be something that interferes with a signal or process. Thus, it is generally thought to be destructive, obscuring signals and interfering with function. However, early in the 20th century, mechanical engineers…

Biological Physics · Physics 2019-06-10 Steven Weinstein , Theodore P. Pavlic

Genes and proteins regulate cellular functions through complex circuits of biochemical reactions. Fluctuations in the components of these regulatory networks result in noise that invariably corrupts the signal, possibly compromising…

Molecular Networks · Quantitative Biology 2016-03-15 Michael Hinczewski , D. Thirumalai

In this paper, we wish to investigate the dynamics of information transfer in evolutionary dynamics. We use information theoretic tools to track how much information an evolving population has obtained and managed to retain about different…

Populations and Evolution · Quantitative Biology 2021-04-09 Nicholas Guttenberg

Exchange of molecules allows cells to exchange information. How robust is the information to changes in cell parameters? We use a mapping between the stochastic dynamics of two cells sharing a stimulatory molecule, and parameters akin to an…

Biological Physics · Physics 2024-07-10 Ismail Qunbar , Michael Vennettilli , Amir Erez

This paper investigates coordination problems over packet-based communication channels. We consider the scenario in which the communication between network nodes is corrupted by unknown-but-bounded noise. We introduce a novel coordination…

Systems and Control · Computer Science 2018-08-14 Mingming Shi , Pietro Tesi , Claudio De Persis

The ability of a cell to communicate with its environment is essential for key cellular functions like replication, metabolism, or cell fate decisions. The involved molecular mechanisms are highly dynamic and difficult to capture…

Human-Computer Interaction · Computer Science 2025-09-11 Lena Cibulski , Fiete Haack , Adelinde Uhrmacher , Stefan Bruckner

We show that intermittency of noiselike emission, after propagation through a scattering medium, affects the distribution of noise in the observed correlation function. Intermittency also affects correlation of noise among channels of the…

Astrophysics of Galaxies · Physics 2015-05-27 Carl R. Gwinn , Michael D. Johnson

A genetic switch may be realised by a certain operator sector on the DNA strand from which either genetic code, to the left or to the right of this operator sector, can be transcribed and the corresponding information processed. This switch…

Statistical Mechanics · Physics 2013-01-24 Ralf Metzler

Our daily social and political life is more and more impacted by social networks. The functioning of our living bodies is deeply dependent on biological regulation networks such as neural, genetic, and protein networks. And the physical…

Discrete Mathematics · Computer Science 2022-04-25 Jacques Demongeot , Tarek Melliti , Mathilde Noual , Damien Regnault , Sylvain Sené