Related papers: Reversibility of Red blood Cell deformation
Modeling of the red blood cell (RBC) shape is an integral part of the experimental and computer simulation investigations of light scattering by these cells for fundamental studies as well as diagnostic applications in techniques like…
We study the shearing rheology of dense suspensions of elastic capsules, taking aggregation-free red blood cells as a physiologically relevant example. Particles are non-Brownian and interact only via hydrodynamics and short-range repulsive…
Bacterial cellulose is an important class of biomaterials which can be grown in well-controlled laboratory and industrial conditions. The cellulose structure is affected by several biological, chemical and environmental factors, including…
How do cells tune emergent properties at the scale of tissues? One class of such emergent behaviors are rigidity transitions, in which a tissue changes from a solid-like to a fluid-like state or vice versa. Here, we introduce a new way for…
Thrombosis is a common complication following the surgical implantation of blood contacting devices, and is strongly influenced by the phenomenon of near-wall enrichment of platelets. This paper describes a multi-constituent continuum…
Cellular adaptation to environmental changes relies on the dynamic remodeling of subcellular structures. Among these, sarcomere structures are fundamental to the organization and function of the cytoskeletal architecture. In muscle-type…
The shape of a cell influences and it is influenced by interactions with its neighbouring partners. Here, we introduce a coarse-grained model of non-reciprocal interactions between single-cell organisms to study emergent morphologies during…
In this paper the bright-field defocusing microscopy (DM) technique is presented. DM is able to obtain quantitative information of each plane/surface of pure phase objects, as live unlabeled cells, and its application to red blood cells…
Identification of abnormalities in red blood cells (RBC) is key to diagnosing a range of medical conditions from anaemia to liver disease. Currently this is done manually, a time-consuming and subjective process. This paper presents an…
We propose a modified suspension balance model (SBM) for the flow of red blood cells (RBCs) and other deformable particle suspensions in confined geometries. Specifically, the method includes the hydrodynamic lift force generated by…
Blue energy represents a large reservoir of renewable osmotic energy that can be converted into electricity by reverse electrodialysis (RED). This method is based on ion-exchange membrane. Before large scale production, these membranes are…
Connecting cell behavior to tissue shape and mechanics is a key challenge in the physics of morphogenesis. Cytoskeletal turnover precludes a fixed reference state, and tensions are actively generated independently of strain; so conventional…
Blood rheology and microcirculation are strongly influenced by red blood cell aggregation. We investigate the dissociation rates of red cell aggregates in extensional flow using hyperbolic microfluidic constrictions and image analysis by a…
Despite the fact that red blood cells carry negative charges, under certain conditions they form cylindrical stacks, or ``rouleaux''. It is shown here that a form of the Casimir effect, generalizing the more well-known van der Waals forces,…
Key to collective cell migration is the ability of cells to rearrange their position with respect to their neighbors. Recent theory and experiments demonstrated that cellular rearrangements are facilitated by cell shape, with cells having…
We present rheology experiments on dilute solutions of vesicles and red blood cells (RBC). Varying the viscosity ratio $\lambda$ between internal and external fluids, the microscopic dynamics of suspended objects can be qualitatively…
Two-dimensional (2D) mechanical models of confluent tissues have related the mechanical state of a monolayer of cells to the average perimeter length of the cell cross sections, predicting floppiness or rigidity of the material. For the…
In processes such as embryo shaping, wound healing, and malignant cell invasion, epithelial cells transition between dispersed phases, where the cells move independently, and condensed phases, where they aggregate and deform to close gaps,…
The initiation of directional cell motion requires symmetry breaking that can happen both with or without external stimuli. During cell crawling, forces generated by the cytoskeleton and their transmission through mechanosensitive adhesions…
Mechanical cues from the extracellular microenvironment play a central role in regulating the structure, function and fate of living cells. Nevertheless, the precise nature of the mechanisms and processes underlying this crucial cellular…