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Motivated by recent epidemic outbreaks, including those of COVID-19, we solve the canonical problem of calculating the dynamics and likelihood of extensive outbreaks in a population within a large class of stochastic epidemic models with…

Populations and Evolution · Quantitative Biology 2022-01-31 Jason Hindes , Michael Assaf , Ira B. Schwartz

Understanding the timing of the peak of a disease outbreak forms an important part of epidemic forecasting. In many cases, such information is essential for planning increased hospital bed demand and for designing of public health…

Populations and Evolution · Quantitative Biology 2023-11-27 Jacob Curran-Sebastian , Lorenzo Pellis , Ian Hall , Thomas House

While a common trend in disease modeling is to develop models of increasing complexity, it was recently pointed out that outbreaks appear remarkably simple when viewed in the incidence vs. cumulative cases (ICC) plane. This article details…

Populations and Evolution · Quantitative Biology 2022-12-26 Faryad Darabi Sahneh , William Fries , Joseph C. Watkins , Joceline Lega

Two simple agent based models are often employed in epidemic studies: the susceptible-infected (SI) and the susceptible-infected-susceptible (SIS). Both models describe the time evolution of infectious diseases in networks in which vertices…

Stochastic epidemic models which incorporate interactions between space and human mobility are a key tool to inform prioritisation of outbreak control to appropriate locations. However, methods for fitting such models to national-level…

This paper studies simultaneous inference of conditional distributions in nonlinear time series from a sieve M-regression perspective. Existing literature on sieve M-regression has primarily focused on pointwise asymptotics, leaving the…

Statistics Theory · Mathematics 2026-05-05 Tianpai Luo , Zhou Zhou

Threshold theorem is probably the most important development of mathematical epidemic modelling. Unfortunately, some models may not behave according to the threshold. In this paper, we will focus on the final outcome of SIR model with…

Populations and Evolution · Quantitative Biology 2018-03-06 Kurnia Susvitasari

The role of epidemiological models is crucial for informing public health officials during a public health emergency, such as the COVID-19 pandemic. However, traditional epidemiological models fail to capture the time-varying effects of…

Methodology · Statistics 2022-06-17 Adam Spannaus , Theodore Papamarkou , Samantha Erwin , J. Blair Christian

Throughout human history, epidemics have been a constant presence. Understanding their dynamics is essential to predict scenarios and make substantiated decisions. Mathematical models are powerful tools to describe an epidemic behavior.…

Systems and Control · Electrical Eng. & Systems 2024-07-26 Walter HMendes aselein , Diego Eckhard

We develop a multiple compartment Susceptible-Infected-Recovered (SIR) model to analyze the spread of several infectious diseases through different geographic areas. Additionally, we propose a data-quality sensitive optimization framework…

Populations and Evolution · Quantitative Biology 2019-06-21 Inbar Seroussi , Nir Levy , Daniela Paolotti , Nir Sochen , Elad Yom-Tov

Multivariate count time series models are an important tool for the analysis and prediction of infectious disease spread. We consider the endemic-epidemic framework, an autoregressive model class for infectious disease surveillance counts,…

Applications · Statistics 2020-03-16 Johannes Bracher , Leonhard Held

Approximating the time to extinction of infection is an important problem in infection modelling. A variety of different approaches have been proposed in the literature. We study the performance of a number of such methods, and characterize…

Probability · Mathematics 2017-07-11 Damian Clancy , Elliott Tjia

Scientific inference involves obtaining the unknown properties or behavior of a system in the light of what is known, typically, without changing the system. Here we propose an alternative to this approach: a system can be modified in a…

Statistical Mechanics · Physics 2019-03-11 Nathaniel Rupprecht , Dervis Vural

In the political decision process and control of COVID-19 (and other epidemic diseases), mathematical models play an important role. It is crucial to understand and quantify the uncertainty in models and their predictions in order to take…

Applications · Statistics 2021-09-17 Bjørn Jensen , Allan P. Engsig-Karup , Kim Knudsen

We develop a feedback control method for networked epidemic spreading processes. In contrast to most prior works which consider mean field, open-loop control schemes, the present work develops a novel framework for feedback control of…

Optimization and Control · Mathematics 2017-03-23 Nicholas J. Watkins , Cameron Nowzari , George J. Pappas

We study the spread of discrete-time epidemics over arbitrary networks for well-known propagation models, namely SIS (susceptible-infected-susceptible), SIR (susceptible-infected-recovered), SIRS (susceptible-infected-recovered-susceptible)…

Social and Information Networks · Computer Science 2016-10-03 Navid Azizan Ruhi , Hyoung Jun Ahn , Babak Hassibi

To better describe the spread of a disease, we extend a discrete time stochastic SIR-type epidemic model of Tuckwell and Williams. We assume the dependence on time of the number of daily encounters and include a parameter to represent a…

Populations and Evolution · Quantitative Biology 2022-09-30 Mireia Besalú , Giulia Binotto

This paper considers a general stochastic SIR epidemic model driven by a multidimensional Levy jump process with heavy tailed increments and possible correlation between noise components. In this framework, we derive new sufficient…

Probability · Mathematics 2020-04-14 Nicolas Privault , Liang Wang

Individual-based models of contagious processes are useful for predicting epidemic trajectories and informing intervention strategies. In such models, the incorporation of contact network information can capture the non-randomness and…

Populations and Evolution · Quantitative Biology 2023-11-09 Maxwell H. Wang , Jukka-Pekka Onnela

In this work, we review the figures used to characterize an epidemic outbreak most. Particular attention is drawn to epidemic spreading at time-varying transition rates. A time-varying SIR-like model is used to describe the epidemic…

Populations and Evolution · Quantitative Biology 2020-11-06 Hernán De Battista , José García-Clúa , Sebastián Nuñez , Fernando Inthamoussou , Fabricio Garelli
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