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Genetic and comparative genomic studies indicate that extant genomes are more properly considered to be a fusion product of random mutations over generations and genomic material transfers between individuals of different lineages. This has…

Quantitative Methods · Quantitative Biology 2018-01-16 Andreas D. M. Gunawan , Bingxin Lu , Louxin Zhang

Phylogenetic Diversity(PD)is a well-regarded measure of the overall biodiversity of a set of present-day species(taxa)that indicates its ecological significance.In the Maximize Phylogenetic Diversity(Max-PD)problem one is asked to find a…

Discrete Mathematics · Computer Science 2025-10-29 Jannik Schestag

A binary tanglegram is a pair <S,T> of binary trees whose leaf sets are in one-to-one correspondence; matching leaves are connected by inter-tree edges. For applications, for example in phylogenetics or software engineering, it is required…

Data Structures and Algorithms · Computer Science 2009-05-15 Martin Nöllenburg , Danny Holten , Markus Völker , Alexander Wolff

A symmetric matrix $C$ is completely positive (CP) if there exists an entrywise nonnegative matrix $B$ such that $C=BB^T$. The CP-completion problem is to study whether we can assign values to the missing entries of a partial matrix (i.e.,…

Optimization and Control · Mathematics 2013-11-21 Anwa Zhou , Jinyan Fan

We construct group codes over two letters (i.e., bases of subgroups of a two-generated free group) with special properties. Such group codes can be used for reducing algorithmic problems over large alphabets to algorithmic problems over a…

Group Theory · Mathematics 2007-05-23 Jean-Camille Birget , Stuart W. Margolis

Construction of phylogenetic trees and networks for extant species from their characters represents one of the key problems in phylogenomics. While solution to this problem is not always uniquely defined and there exist multiple methods for…

Populations and Evolution · Quantitative Biology 2016-08-10 Nikita Alexeev , Max A. Alekseyev

The matrix completion problem provides a unifying lens through which many fundamental problems in coding theory can be viewed. In this paper, we investigate Locally Recoverable Codes (LRCs) with Maximal Recoverability (MR) and Maximum…

Information Theory · Computer Science 2026-04-24 Sakshi Dang , Julia Lieb , Pedro Soto , Alex Sprintson

Deciding whether a graph can be embedded in a grid using only unit-length edges is NP-complete, even when restricted to binary trees. However, it is not difficult to devise a number of graph classes for which the problem is polynomial, even…

Data Structures and Algorithms · Computer Science 2012-04-13 Vinícius G. P. de Sá , Guilherme D. da Fonseca , Raphael Machado , Celina M. H. de Figueiredo

Inferring concerted changes among biological traits along an evolutionary history remains an important yet challenging problem. Besides adjusting for spurious correlation induced from the shared history, the task also requires sufficient…

Rooted binary perfect phylogenies provide a generalization of rooted binary unlabeled trees in which each leaf is assigned a positive integer value that corresponds in a biological setting to the count of the number of indistinguishable…

Populations and Evolution · Quantitative Biology 2024-10-22 Chloe E. Shiff , Noah A. Rosenberg

Technical signs of progress during the last decades has led to a situation in which the accumulation of genome sequence data is increasingly fast and cheap. The huge amount of molecular data available nowadays can help addressing new and…

Genomics · Quantitative Biology 2017-05-02 Christophe Guyeux , Bashar Al-Nuaimi , Bassam AlKindy , Jean-François Couchot , Michel Salomon

The problem Parsimony Haplotyping (PH) asks for the smallest set of haplotypes which can explain a given set of genotypes, and the problem Minimum Perfect Phylogeny Haplotyping (MPPH) asks for the smallest such set which also allows the…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Leo van Iersel , Judith Keijsper , Steven Kelk , Leen Stougie

Exact string matching has been a fundamental problem in computer science for decades because of many practical applications. Some are related to common procedures, such as searching in files and text editors, or, more recently, to more…

Data Structures and Algorithms · Computer Science 2019-07-29 Konstantinos F. Xylogiannopoulos

In this article, we investigate different parsimony-based approaches towards finding recombination breakpoints in a multiple sequence alignment. This recombination detection task is crucial in order to avoid errors in evolutionary analyses…

Populations and Evolution · Quantitative Biology 2019-10-25 Mark Jones , Philippe Gambette , Leo van Iersel , Remie Janssen , Steven Kelk , Fabio Pardi , Celine Scornavacca

A complete classification of the perfect binary one-error-correcting codes of length 15 as well as their extensions of length 16 was recently carried out in [P. R. J. \"Osterg{\aa}rd and O. Pottonen, "The perfect binary one-error-correcting…

Information Theory · Computer Science 2010-10-07 Patric R. J. Östergård , Olli Pottonen , Kevin T. Phelps

Clique-width is a well-studied graph parameter owing to its use in understanding algorithmic tractability: if the clique-width of a graph class ${\cal G}$ is bounded by a constant, a wide range of problems that are NP-complete in general…

Combinatorics · Mathematics 2021-12-23 Konrad K. Dabrowski , Matthew Johnson , Daniël Paulusma

Reconstructing ancestral gene orders is an important step towards understanding genome evolution. The Small Parsimony Problem (SPP) has been extensively studied in this regard. The problem aims at finding the gene orders at internal nodes…

Data Structures and Algorithms · Computer Science 2021-08-11 Daniel Doerr , Cedric Chauve

A phylogenetic tree is a graphical representation of an evolutionary history of taxa in which the leaves correspond to the taxa and the non-leaves correspond to speciations. One of important problems in phylogenetic analysis is to assemble…

Combinatorics · Mathematics 2022-02-25 Hiroshi Hirai , Yuni Iwamasa

Efficiently finding the maximum a posteriori (MAP) configuration of a graphical model is an important problem which is often implemented using message passing algorithms. The optimality of such algorithms is only well established for…

Artificial Intelligence · Computer Science 2012-05-14 Tony S. Jebara

We study distributed algorithms for string matching problem in presence of wildcard characters. Given a string T (a text), we look for all occurrences of another string P (a pattern) as a substring of string T . Each wildcard character in…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-06-08 MohammadTaghi Hajiaghayi , Hamed Saleh , Saeed Seddighin , Xiaorui Sun
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