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This paper discusses scalability of standard genetic programming (GP) and the probabilistic incremental program evolution (PIPE). To investigate the need for both effective mixing and linkage learning, two test problems are considered:…

Neural and Evolutionary Computing · Computer Science 2007-05-23 Radovan Ondas , Martin Pelikan , Kumara Sastry

We introduce a binary embedding framework, called Proximity Preserving Code (PPC), which learns similarity and dissimilarity between data points to create a compact and affinity-preserving binary code. This code can be used to apply fast…

Machine Learning · Computer Science 2020-02-06 Inbal Lav , Shai Avidan , Yoram Singer , Yacov Hel-Or

Binary (0-1) integer programming (BIP) is pivotal in scientific domains requiring discrete decision-making. As the advance of AI computing, recent works explore neural network-based solvers for integer linear programming (ILP) problems.…

Machine Learning · Computer Science 2025-05-28 Sen Bai , Chunqi Yang , Xin Bai , Xin Zhang , Zhengang Jiang

In evolutionary biology, phylogenetic trees are commonly inferred from a set of characters (partitions) of a collection of biological entities (e.g., species or individuals in a population). Such characters naturally arise from molecular…

Populations and Evolution · Quantitative Biology 2023-11-17 Katharina T. Huber , Simone Linz , Vincent Moulton , Charles Semple

Recently, the perfect phylogeny model with persistent characters has attracted great attention in the literature. It is based on the assumption that complex traits or characters can only be gained once and lost once in the course of…

Combinatorics · Mathematics 2021-06-08 Remco Bouckaert , Mareike Fischer , Kristina Wicke

In the Maximize Phylogenetic Diversity problem, we are given a phylogenetic tree that represents the genetic proximity of species, and we are asked to select a subset of species of maximum phylogenetic diversity to be preserved through…

Computational Complexity · Computer Science 2026-02-16 Niels Holtgrefe , Jannik Schestag , Norbert Zeh

Phylogenetic networks are increasingly used in evolutionary biology to represent the history of species that have undergone reticulate events such as horizontal gene transfer, hybrid speciation and recombination. One of the most fundamental…

Populations and Evolution · Quantitative Biology 2016-10-07 Philippe Gambette , Leo van Iersel , Steven Kelk , Fabio Pardi , Celine Scornavacca

Hairpin completion and its variant called bounded hairpin completion are operations on formal languages, inspired by a hairpin formation in molecular biology. Another variant called hairpin lengthening has been recently introduced and…

Formal Languages and Automata Theory · Computer Science 2011-11-28 Fumiya Okubo , Takashi Yokomori

We study the complexity of the problem of searching for a set of patterns that separate two given sets of strings. This problem has applications in a wide variety of areas, most notably in data mining, computational biology, and in…

Computational Complexity · Computer Science 2016-12-20 Giuseppe Lancia , Luke Mathieson , Pablo Moscato

This paper addresses the online exact string matching problem which consists in finding all occurrences of a given pattern p in a text t. It is an extensively studied problem in computer science, mainly due to its direct applications to…

Data Structures and Algorithms · Computer Science 2010-12-14 Simone Faro , Thierry Lecroq

We describe two BQP-complete problems concerning properties of sparse graphs having a certain symmetry. The graphs are specified by efficiently computable functions which output the adjacent vertices for each vertex. Let i and j be two…

Quantum Physics · Physics 2007-05-23 Dominik Janzing , Pawel Wocjan

A pattern p (i.e., a string of variables and terminals) matches a word w, if w can be obtained by uniformly replacing the variables of p by terminal words. The respective matching problem, i.e., deciding whether or not a given pattern…

Data Structures and Algorithms · Computer Science 2019-07-30 Florin Manea , Markus L. Schmid

Over the past two decades, a series of works have aimed at studying the problem of genome assembly: the process of reconstructing a genome from sequence reads. An early formulation of the genome assembly problem showed that genome…

Genomics · Quantitative Biology 2013-12-30 Henry Lin

Completion problems, of recovering a point from a set of observed coordinates, are abundant in applications to image reconstruction, phylogenetics, and data science. We consider a completion problem coming from algebraic statistics: to…

Statistics Theory · Mathematics 2024-12-04 May Cai , Cecilie Olesen Recke , Thomas Yahl

The graph coloring problem (GCP) is one of the most studied NP-HARD problems in computer science. Given a graph , the task is to assign a color to all vertices such that no vertices sharing an edge receive the same color and that the number…

Neural and Evolutionary Computing · Computer Science 2021-11-19 Robiul Islam , Arup Kumar Pramanik

Given an integer $k$ and a graph where every edge is colored either red or blue, the goal of the exact matching problem is to find a perfect matching with the property that exactly $k$ of its edges are red. Soon after Papadimitriou and…

Data Structures and Algorithms · Computer Science 2023-10-02 Nicolas {El Maalouly} , Raphael Steiner , Lasse Wulf

We show that the problem of counting perfect matchings remains #P-complete even if we restrict the input to very dense graphs, proving the conjecture in [5]. Here "dense graphs" refer to bipartite graphs of bipartite independence number…

Data Structures and Algorithms · Computer Science 2022-10-28 Nicolas El Maalouly , Yanheng Wang

NP complete problem is one of the most challenging issues. The question of whether all problems in NP are also in P is generally considered one of the most important open questions in mathematics and theoretical computer science as it has…

Computational Complexity · Computer Science 2015-05-04 Wenhong Tian , GuoZhong Li , Xinyang Wang , Qin Xiong , Yaqiu Jiang

We present a quantum algorithm in bioinformatics for solving the Binary Near-Perfect Phylogeny Problem (BNPP) with a complexity bound of $O(8.926^q + 8^q nm2)$, where n is the number of input taxa and m is the sequence length for each taxon…

Quantum Physics · Physics 2025-10-14 Lingfa Meng , David Salvador Novo , Albert H. Werner , Samir Bhatt

Phylogenetic trees canonically arise as embeddings of phylogenetic networks. We recently showed that the problem of deciding if two phylogenetic networks embed the same sets of phylogenetic trees is computationally hard, \blue{in…

Combinatorics · Mathematics 2021-04-13 Janosch Doecker , Simone Linz , Charles Semple