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The simulation hypothesis has recently excited renewed interest in the physics and philosophy communities. However, the hypothesis specifically concerns {\textit{computers}} that simulate physical universes. So to formally investigate the…

Logic in Computer Science · Computer Science 2026-03-20 David H. Wolpert

The traditional foundation of science lies on the cornerstones of theory and experiment. Theory is used to explain experiment, which in turn guides the development of theory. Since the advent of computers and the development of…

Computational Physics · Physics 2023-11-14 Susi Lehtola

Living systems are subject to the arrow of time; from birth, they undergo complex transformations (self-organization) in a constant battle for survival, but inevitably ageing and disease trap them to death. Can ageing be understood and…

Other Quantitative Biology · Quantitative Biology 2020-08-21 Tamàs Fülöp , Mathieu Desroches , Fernando Antônio Nóbrega Santos , Serafim Rodrigues

Why are living systems complex? Why does the biosphere contain living beings with complexity features beyond those of the simplest replicators? What kind of evolutionary pressures result in more complex life forms? These are key questions…

Populations and Evolution · Quantitative Biology 2023-11-13 Seoane LF , Solé R

Composition is a powerful principle for systems biology, focused on the interfaces, interconnections, and orchestration of distributed processes to enable integrative multiscale simulations. Whereas traditional models focus on the structure…

Other Quantitative Biology · Quantitative Biology 2024-11-25 Eran Agmon

Computing is a high-level process of a physical system. Recent interest in non-standard computing systems, including quantum and biological computers, has brought this physical basis of computing to the forefront. There has been, however,…

Emerging Technologies · Computer Science 2023-04-21 Dominic Horsman , Susan Stepney , Rob C. Wagner , Viv Kendon

A distributed computing system is a collection of processors that communicate either by reading and writing from a shared memory or by sending messages over some communication network. Most prior biologically inspired distributed computing…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-05-15 Sabrina Rashid , Gadi Taubenfeld , Ziv Bar-Joseph

This paper investigates the view that digital hypercomputing is a good reason for rejection or re-interpretation of the Church-Turing thesis. After suggestion that such re-interpretation is historically problematic and often involves attack…

Logic in Computer Science · Computer Science 2025-05-22 Vincent C. Müller

The molecular biology revolution of the last seventy five years has transformed our view of living systems. Scientific explanations of biological phenomena are now synonymous with the identification of the genes, proteins, and signaling…

Biological Physics · Physics 2024-10-29 Pankaj Mehta

As computer scientists working in bioinformatics/computational biology, we often face the challenge of coming up with an algorithm to answer a biological question. This occurs in many areas, such as variant calling, alignment, and assembly.…

Data Structures and Algorithms · Computer Science 2018-01-04 Paul Medvedev

In the last few decades or so, we witness a paradigm shift in our nature studies - from a data-processing based computational approach to an information-processing based cognitive approach. The process is restricted and often misguided by…

Computational Engineering, Finance, and Science · Computer Science 2015-05-20 Emanuel Diamant

Alan Turing's pioneering work on computability, and his ideas on morphological computing support Andrew Hodges' view of Turing as a natural philosopher. Turing's natural philosophy differs importantly from Galileo's view that the book of…

General Literature · Computer Science 2012-07-05 Gordana Dodig-Crnkovic

Biological systems are generally complicated and/or complex. In the former approach, one sets up a model with a large number of parameters to describe the system in detail. The latter approach focuses on understanding the universal aspects…

Biological Physics · Physics 2026-03-19 Kunihiko Kaneko

A biological circuit is a neural or biochemical cascade, taking inputs and producing outputs. How have biological circuits learned to solve environmental challenges over the history of life? The answer certainly follows Dobzhansky's famous…

Populations and Evolution · Quantitative Biology 2025-10-30 Steven A. Frank

Over the past two decades the field of computational science and engineering (CSE) has penetrated both basic and applied research in academia, industry, and laboratories to advance discovery, optimize systems, support decision-makers, and…

Quantum computing, leveraging quantum phenomena like superposition and entanglement, is emerging as a transformative force in computing technology, promising unparalleled computational speed and efficiency crucial for engineering…

Quantum Physics · Physics 2024-08-30 Osama Muhammad Raisuddin , Suvranu De

We start with a discussion of the relevant literature, including Nature Inspired Computing as a framework in which to understand this work, and the process of biomimicry to be used in mimicking the necessary biological processes to create…

Neural and Evolutionary Computing · Computer Science 2012-11-28 G Briscoe

Systems are growing into more complex ones for developing and maintaining. Existing systems which do not have much in common on the first look are connected, due to the technical progress, even if it was never intended that way. It is an…

Software Engineering · Computer Science 2018-09-17 Tobias Eckl

Currently, CyberPhysical Systems (CPS) represents a great challenge for automatic control and smart systems engineering on both theoretical and practical levels. Designing CPS requires approaches involving multidisciplinary competences.…

Quantitative Methods · Quantitative Biology 2016-01-27 Didier Fass , Franck Gechter

Biological organisms are composed of numerous interconnected biochemical processes. Diseases occur when normal functionality of these processes is disrupted. Thus, understanding these biochemical processes and their interrelationships is a…

Artificial Intelligence · Computer Science 2014-03-04 Saadat Anwar