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The Church-Turing thesis states that any sufficiently powerful computational model which captures the notion of algorithm is computationally equivalent to the Turing machine. This equivalence usually holds both at a computability level and…

Computational Complexity · Computer Science 2017-01-18 Amaury Pouly , Olivier Bournez , Daniel S. Graça

Deep learning has become a powerful tool in computational biology, revolutionising the analysis and interpretation of biological data over time. In our article review, we delve into various aspects of deep learning in computational biology.…

Self-replication is central to all life, and yet how it dynamically emerges in physical, non-equilibrium systems remains poorly understood. Von Neumann's pioneering work in the 1940s and subsequent developments suggest a natural hypothesis:…

Cellular Automata and Lattice Gases · Physics 2025-10-10 Jordan Cotler , Clément Hongler , Barbora Hudcová

With the great success in simulating many intelligent behaviors using computing devices, there has been an ongoing debate whether all conscious activities are computational processes. In this paper, the answer to this question is shown to…

Quantum Physics · Physics 2011-11-09 Daegene Song

The genetic blueprint for the essential functions of life is encoded in DNA, which is translated into proteins -- the engines driving most of our metabolic processes. Recent advancements in genome sequencing have unveiled a vast diversity…

Neural and Evolutionary Computing · Computer Science 2024-06-12 James S. L. Browning , Daniel R. Tauritz , John Beckmann

Interest in the thermodynamics of computation has revived in recent years, driven by developments in science, economics and technology. Given the consequences of the growing demand for computational power, the idea of reducing the energy…

Statistical Mechanics · Physics 2018-12-31 Thomas E Ouldridge , Rory A. Brittain , Pieter Rein ten Wolde

Human societies continuously transform scattered information into collective judgments and coordinated action, whether through markets discovering prices, governments allocating resources, communities enforcing norms, or science converging…

The purpose of this thesis is to make an analysis of the concept of Hypercomputation and of some hypermachines. This thesis is separated in three main parts. We start in the first chapter with an analysis of the concept of Classical…

Computational Complexity · Computer Science 2012-10-29 Gentian Kasa

Epigenetic Tracking (ET) is an Artificial Embryology system which allows for the evolution and development of large complex structures built from artificial cells. In terms of the number of cells, the complexity of the bodies generated with…

Computational Engineering, Finance, and Science · Computer Science 2013-10-01 Alessandro Fontana , Borys Wróbel

Computational models are invaluable in capturing the complexities of real-world biological processes. Yet, the selection of appropriate algorithms for inference tasks, especially when dealing with real-world observational data, remains a…

Applications · Statistics 2024-10-01 Xiaoyu Wang , Ryan P. Kelly , Adrianne L. Jenner , David J. Warne , Christopher Drovandi

We study open-ended evolution by focusing on computational and information-processing dynamics underlying major evolutionary transitions. In doing so, we consider biological organisms as hierarchical dynamical systems that generate…

Biology is data-rich, and it is equally rich in concepts and hypotheses. Part of trying to understand biological processes and systems is therefore to confront our ideas and hypotheses with data using statistical methods to determine the…

Quantitative Methods · Quantitative Biology 2022-06-22 Sean T. Vittadello , Michael P. H. Stumpf

Computational problems are classified into computable and uncomputable problems. If there exists an effective procedure (algorithm) to compute a problem then the problem is computable otherwise it is uncomputable. Turing machines can…

Computational Complexity · Computer Science 2024-09-06 Asad Khaliq

There are enormous amount of examples of Computation in nature, exemplified across multiple species in biology. One crucial aim for these computations across all life forms their ability to learn and thereby increase the chance of their…

Machine Learning · Computer Science 2013-12-30 Nabarun Mondal , Partha P. Ghosh

Our understanding of the physics of biological molecules, such as proteins and DNA, is limited because the approximations we usually apply to model inert materials are not in general applicable to soft, chemically inhomogeneous systems. The…

Quantum Physics · Physics 2010-07-13 Sarah Harris , Vivien M. Kendon

Understanding large molecular networks consisting of entities such as genes, proteins or RNAs that interact in complex ways to drive the cellular machinery has been an active focus of systems biology. Computational approaches have played a…

Molecular Networks · Quantitative Biology 2013-04-23 Sriganesh Srihari , Mark A. Ragan

For over a decade, the hypercomputation movement has produced computational models that in theory solve the algorithmically unsolvable, but they are not physically realizable according to currently accepted physical theories. While…

Logic · Mathematics 2014-08-12 Aran Nayebi

A main challenge of data-driven sciences is how to make maximal use of the progressively expanding databases of experimental datasets in order to keep research cumulative. We introduce the idea of a modeling-based dataset retrieval engine…

Quantitative Methods · Quantitative Biology 2015-06-19 Ali Faisal , Jaakko Peltonen , Elisabeth Georgii , Johan Rung , Samuel Kaski

Independent computational reproducibility of scientific results is rapidly becoming of pivotal importance in scientific progress as computation itself plays a more and more central role in so many branches of science. Historically,…

Quantitative Methods · Quantitative Biology 2016-08-25 Les Hatton , Gregory Warr

Computation is commonly defined as the execution of abstract algorithms over symbolic representations, with physical systems treated as substrates that realise predefined operations. While effective for engineered machines, this separation…

Physics and Society · Physics 2026-01-21 Kimia Witte
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