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Related papers: Multiscale simulation of blood flow in brain arter…

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Cerebrovascular diseases such as brain aneurysms are a primary cause of adult disability. The flow dynamics in brain arteries, both during periods of rest and increased activity, are known to be a major factor in the risk of aneurysm…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-04-30 Mohamed A. Itani , Ulf D. Schiller , Sebastian Schmieschek , James Hetherington , Miguel O. Bernabeu , Hoskote Chandrashekar , Fergus Robertson , Peter V. Coveney , Derek Groen

It is known that the maximum diameter for the rupture-risk assessment of the abdominal aortic aneurysm is a generally good method, but not sufficient. Alternative features obtained with computational modeling may provide additional useful…

Computational Engineering, Finance, and Science · Computer Science 2020-03-16 Shanlin Qin , Rongliang Chen , Bokai Wu , Jia Liu , Wen-Shin Shiu , Zhengzheng Yan , Xiao-Chuan Cai

Investigating blood flow in the cardiovascular system is crucial for assessing cardiovascular health. Computational approaches offer some non-invasive alternatives to measure blood flow dynamics. Numerical simulations based on traditional…

Numerical Analysis · Mathematics 2024-06-07 Han Zhang , Raymond Chan , Xue-Cheng Tai

In the last years, medical computer simulation has seen a great growth in several scientific branches, from modelling to numerical methods, going through computer science. The main goals of this incipient discipline are testing hypotheses…

Fluid Dynamics · Physics 2017-10-20 Cristóbal Rodero Gómez

Computational fluid dynamics (CFD) is increasingly used to study blood flows in patient-specific arteries for understanding certain cardiovascular diseases. The techniques work quite well for relatively simple problems, but need…

Computational Physics · Physics 2018-10-11 Fande Kong , Vitaly Kheyfets , Ender Finol , Xiao-Chuan Cai

Cardiovascular disease affects millions of people worldwide and its social and economic cost clearly motivates scientific research. Computer simulation can lead to a better understanding of cardiac physiology, and for pathology presents…

Biological Physics · Physics 2023-02-27 Toby Simpson

Human blood flow is a multi-scale problem: in first approximation, blood is a dense suspension of plasma and deformable red cells. Physiological vessel diameters range from about one to thousands of cell radii. Current computational models…

Soft Condensed Matter · Physics 2015-03-17 Florian Janoschek , Federico Toschi , Jens Harting

Predicting the long-term success of endovascular interventions in the clinical management of cerebral aneurysms requires detailed insight into the patient-specific physiological conditions. In this work, we not only propose numerical…

Particle accelerator modeling is an important field of research and development, essential to investigating, designing and operating some of the most complex scientific devices ever built. Kinetic simulations of relativistic, charged…

Accelerator Physics · Physics 2024-05-02 Ryan T. Sandberg , Remi Lehe , Chad E. Mitchell , Marco Garten , Andrew Myers , Ji Qiang , Jean-Luc Vay , Axel Huebl

Background and Objective: This study aims to evaluate the dynamic effect of non-Newtonian cerebral arterial circulation on electrical conductivity distribution (ECD) in a realistic multi-compartment head model. It addresses the importance…

Analysis of PDEs · Mathematics 2023-05-31 Maryam Samavaki , Arash Zarrin Nia , Santtu Söderholm , Sampsa Pursiainen

We present the first mathematical model of flow-mediated primary hemostasis in an extravascular injury, which can track the process from initial deposition to occlusion. The model consists of a system of ordinary differential equations…

Cell Behavior · Quantitative Biology 2020-03-05 Kathryn G. Link , Matthew G. Sorrells , Nicholas A. Danes , Keith B. Neeves , Karin Leiderman , Aaron L. Fogelson

When a blood vessel ruptures or gets inflamed, the human body responds by rapidly forming a clot to restrict the loss of blood. Platelets aggregation at the injury site of the blood vessel occurring via platelet-platelet adhesion, tethering…

Tissues and Organs · Quantitative Biology 2015-06-18 Ziheng Wu , Zhiliang Xu , Oleg Kim , Mark Alber

Currently, it is challenging to investigate aneurismal hemodynamics based on current in-vivo data such as Magnetic Resonance Imaging or Computed Tomography due to the limitations in both spatial and temporal resolutions. In this work, we…

Fluid Dynamics · Physics 2024-10-17 Thien-Tam Nguyen , Davina Kasperski , Phat Kim Huynh , Trung Quoc Le , Trung Bao Le

We are interested in a reduced order method for the efficient simulation of blood flow in arteries. The blood dynamics is modeled by means of the incompressible Navier-Stokes equations. Our algorithm is based on an approximated…

Numerical Analysis · Mathematics 2021-04-07 Luca Pegolotti , Martin Pfaller , Alison Marsden , Simone Deparis

Blood clotting involves the coupled processes of platelet aggregation and coagulation. Simulating clotting under flow in complex geometries is challenging due to multiple temporal and spatial scales and high computational cost. clotFoam is…

Fluid Dynamics · Physics 2023-08-07 David Montgomery , Federico Municchi , Karin Leiderman

Background and Objective: Hemodynamic analysis of blood flow through arteries and veins is critical for diagnosing cardiovascular diseases, such as aneurysms and stenoses, and for investigating cardiovascular parameters, such as turbulence…

We present a novel framework to explore neural control and design of complex fluidic systems with dynamic solid boundaries. Our system features a fast differentiable Navier-Stokes solver with solid-fluid interface handling, a…

Fluid Dynamics · Physics 2024-11-04 Yifei Li , Yuchen Sun , Pingchuan Ma , Eftychios Sifakis , Tao Du , Bo Zhu , Wojciech Matusik

Discrete particle simulations are widely used to study large-scale particulate flows in complex geometries where particle-particle and particle-fluid interactions require an adequate representation but the computational cost has to be kept…

Computational Engineering, Finance, and Science · Computer Science 2017-11-02 Christoph Rettinger , Ulrich Rüde

Cardiovascular diseases, specifically cerebral aneurysms, represent a major cause of morbidity and mortality, having a significant impact on the cost and overall status of health care. In the present work, we employ a haemorheological blood…

Fluid Dynamics · Physics 2023-10-23 Kamyar Behrouzi , Zahra Khodabakhshi Fard , Azadeh Jafari , Robert G. Owens

We propose a highly versatile computational framework for the simulation of cellular blood flow focusing on extreme performance without compromising accuracy or complexity. The tool couples the lattice Boltzmann solver Palabos for the…

Computational Physics · Physics 2021-07-22 Christos Kotsalos , Jonas Latt , Joel Beny , Bastien Chopard
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