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Privacy-preserving genomic data sharing is prominent to increase the pace of genomic research, and hence to pave the way towards personalized genomic medicine. In this paper, we introduce ($\epsilon , T$)-dependent local differential…

Cryptography and Security · Computer Science 2021-02-16 Emre Yilmaz , Tianxi Ji , Erman Ayday , Pan Li

In this paper we describe a new technique for the comparison of populations of DNA strands. Comparison is vital to the study of ecological systems, at both the micro and macro scales. Existing methods make use of DNA sequencing and cloning,…

Biomolecules · Quantitative Biology 2008-07-02 Dennis Shasha , Martyn Amos

The generation of privacy-preserving synthetic datasets is a promising avenue for overcoming data scarcity in medical AI research. Post-hoc privacy filtering techniques, designed to remove samples containing personally identifiable…

Machine Learning · Computer Science 2025-10-03 Adil Koeken , Alexander Ziller , Moritz Knolle , Daniel Rueckert

The modeling of genomic sequences presents unique challenges due to their length and structural complexity. Traditional sequence models struggle to capture long-range dependencies and biological features inherent in DNA. In this work, we…

Computational Engineering, Finance, and Science · Computer Science 2026-03-09 Qirong Yang , Yucheng Guo , Zicheng Liu , Yujie Yang , Qijin Yin , Siyuan Li , Shaomin Ji , Linlin Chao , Xiaoming Zhang , Stan Z. Li

Mining health data can lead to faster medical decisions, improvement in the quality of treatment, disease prevention, reduced cost, and it drives innovative solutions within the healthcare sector. However, health data is highly sensitive…

Cryptography and Security · Computer Science 2022-04-28 Iyiola E. Olatunji , Jens Rauch , Matthias Katzensteiner , Megha Khosla

Since the arrival of next-generation sequencing technologies the amount of genetic sequencing data has increased dramatically. This has has fueled an increase in human genetics research. At the same time, with the recent advent of…

Genomics · Quantitative Biology 2016-07-04 Kristiina Ausmees , Pushpam Aji John

The rapid growth in digital data forms the basis for a wide range of new services and research, e.g, large-scale medical studies. At the same time, increasingly restrictive privacy concerns and laws are leading to significant overhead in…

Cryptography and Security · Computer Science 2021-09-06 Bernardo A. Huberman , Tad Hogg

Contact tracing is a very powerful method to implement and enforce social distancing to avoid spreading of infectious diseases. The traditional approach of contact tracing is time consuming, manpower intensive, dangerous and prone to error…

Machine Learning · Computer Science 2020-04-29 Manish Shukla , Rajan M A , Sachin Lodha , Gautam Shroff , Ramesh Raskar

Summary: With the rapid development of long-read sequencing technologies, the era of individual complete genomes is approaching. We have developed wgatools, a cross-platform, ultrafast toolkit that supports a range of whole genome alignment…

Genomics · Quantitative Biology 2025-04-01 Wenjie Wei , Songtao Gui , Jian Yang , Erik Garrison , Jianbing Yan , Hai-Jun Liu

The scientific method presents a key challenge to privacy because it requires many samples to support a claim. When samples are commercially valuable or privacy-sensitive enough, their owners have strong reasons to avoid releasing them for…

Cryptography and Security · Computer Science 2021-10-05 Andrew Trask , Kritika Prakash

With smartphone technologies enhanced way of interacting with the world around us, it has also been paving the way for easier access to our private and personal information. This has been amplified by the existence of numerous embedded…

Cryptography and Security · Computer Science 2020-07-10 Tanusree Sharma , Masooda Bashir

This study analyzes rates and ways of data sharing regarding mitochondrial, Y chromosomal and autosomal polymorphisms in a total of 162 papers on human ancient DNA published between 1988 and 2013. For the most part, data are available in…

Populations and Evolution · Quantitative Biology 2015-08-19 Paolo Anagnostou , Marco Capocasa , Nicola Milia , Emanuele Sanna , Daniela Luzi , Giovanni Destro Bisol

The collection and sharing of genomic data are becoming increasingly commonplace in research, clinical, and direct-to-consumer settings. The computational protocols typically adopted to protect individual privacy include sharing summary…

Cryptography and Security · Computer Science 2023-02-06 Rajagopal Venkatesaramani , Zhiyu Wan , Bradley A. Malin , Yevgeniy Vorobeychik

The ominous warnings of a `data deluge' in the life sciences from high-throughput DNA sequencing data are being supplanted by a second deluge, of cliches bemoaning our collective scientific fate unless we address the genomic data `tsunami'.…

Genomics · Quantitative Biology 2013-08-16 Aaron Golden , S. George Djorgovski , John M. Greally

The modern society, economy and industry have been changed remarkably by many cutting-edge technologies over the last years, and many more are in development and early implementation that will in turn led even wider spread of adoptions and…

Cryptography and Security · Computer Science 2020-09-02 Phan The Duy , Do Thi Thu Hien , Van-Hau Pham

Differential privacy is a leading protection setting, focused by design on individual privacy. Many applications, in medical / pharmaceutical domains or social networks, rather posit privacy at a group level, a setting we call integral…

Machine Learning · Statistics 2019-07-04 Hisham Husain , Zac Cranko , Richard Nock

Record linkage has been extensively used in various data mining applications involving sharing data. While the amount of available data is growing, the concern of disclosing sensitive information poses the problem of utility vs privacy. In…

Databases · Computer Science 2012-08-15 Luca Bonomi , Li Xiong , Rui Chen , Benjamin C. M. Fung

DNA sequence encoding is fundamental to gene function prediction, protein synthesis, and diverse downstream biological tasks. Despite the substantial progress achieved by large-scale DNA sequence pretraining, existing studies have…

Machine Learning · Computer Science 2026-04-21 Zhijiang Tang , Jiaxin Qi , Yan Cui , Jinli Ou , Yuhua Zheng , Jianqiang Huang

Commercial companies that collect user data on a large scale have been the main beneficiaries of this trend since the success of deep learning techniques is directly proportional to the amount of data available for training. Massive data…

Cryptography and Security · Computer Science 2020-06-30 Saichethan Miriyala Reddy , Saisree Miriyala

As people across the world become increasingly aware of how their privacy is compromised in this digital era, the field of Privacy Enhancing Technologies, or PETs, has boomed. The first workshop on Privacy Enhancing Technology was in 2000,…

Cryptography and Security · Computer Science 2020-01-03 Sarah Cline , Jacob Aronoff