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Motivation: Human genomic datasets often contain sensitive information that limits use and sharing of the data. In particular, simple anonymisation strategies fail to provide sufficient level of protection for genomic data, because the data…

Quantitative Methods · Quantitative Biology 2019-08-27 Teppo Niinimäki , Mikko Heikkilä , Antti Honkela , Samuel Kaski

Genetic data collection has become ubiquitous, producing genetic information about health, ancestry, and social traits. However, unregulated use, especially amid evolving scientific understanding, poses serious privacy and discrimination…

Computers and Society · Computer Science 2025-06-03 Vivek Ramanan , Ria Vinod , Cole Williams , Sohini Ramachandran , Suresh Venkatasubramanian

Deep generative models open new avenues for simulating realistic genomic data while preserving privacy and addressing data accessibility constraints. While previous studies have primarily focused on generating gene expression or haplotype…

Genomics · Quantitative Biology 2025-08-14 Sihan Xie , Thierry Tribout , Didier Boichard , Blaise Hanczar , Julien Chiquet , Eric Barrey

Developments in Genome-Wide Association Studies have led to the increasing notion that future healthcare techniques will be personalized to the patient, by relying on genetic tests to determine the risk of developing a disease. To this end,…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-01-27 Diogo Marques , Rafael Campos , Sergio Santander-Jiménez , Zakhar Matveev , Leonel Sousa , Aleksandar Ilic

Recent advances in deep generative models have greatly expanded the potential to create realistic synthetic health datasets. These synthetic datasets aim to preserve the characteristics, patterns, and overall scientific conclusions derived…

Machine Learning · Computer Science 2024-07-04 Jennifer A Bartell , Sander Boisen Valentin , Anders Krogh , Henning Langberg , Martin Bøgsted

Powerful recognition algorithms are widely used in the Internet or important medical systems, which poses a serious threat to personal privacy. Although the law provides for diversity protection, e.g. The General Data Protection Regulation…

Cryptography and Security · Computer Science 2022-02-15 Hao Wang , Yu Bai , Guangmin Sun , Jie Liu

Generative AI technologies are gaining unprecedented popularity, causing a mix of excitement and apprehension through their remarkable capabilities. In this paper, we study the challenges associated with deploying synthetic data, a subfield…

Machine Learning · Computer Science 2023-07-11 Lauren Arthur , Jason Costello , Jonathan Hardy , Will O'Brien , James Rea , Gareth Rees , Georgi Ganev

Sharing data can often enable compelling applications and analytics. However, more often than not, valuable datasets contain information of a sensitive nature, and thus, sharing them can endanger the privacy of users and organizations. A…

Cryptography and Security · Computer Science 2024-02-28 Emiliano De Cristofaro

While artificial intelligence (AI) has become widespread, many commercial AI systems are not yet accessible to individual researchers nor the general public due to the deep knowledge of the systems required to use them. We believe that AI…

With recent high-throughput technology we can synthesize large heterogeneous collections of DNA structures, and also read them all out precisely in a single procedure. Can we use these tools, not only to do things faster, but also to devise…

Data Structures and Algorithms · Computer Science 2021-12-07 Luca Cardelli

Real-time, online-editing web apps provide free and convenient services for collaboratively editing, sharing and storing files. The benefits of these web applications do not come for free: not only do service providers have full access to…

Cryptography and Security · Computer Science 2019-11-19 Yihao Hu , Ari Trachtenberg , Prakash Ishwar

The widespread adoption of electronic health records and digital healthcare data has created a demand for data-driven insights to enhance patient outcomes, diagnostics, and treatments. However, using real patient data presents privacy and…

Machine Learning · Computer Science 2023-11-15 Aryan Jadon , Shashank Kumar

Over the past years, deep learning capabilities and the availability of large-scale training datasets advanced rapidly, leading to breakthroughs in face recognition accuracy. However, these technologies are foreseen to face a major…

Computer Vision and Pattern Recognition · Computer Science 2023-05-03 Fadi Boutros , Vitomir Struc , Julian Fierrez , Naser Damer

Processing high-throughput DNA sequencing data of individuals or populations requires stringing together independent software tools with many parameters, often leading to non-reproducible pipelines and datasets. We developed grenepipe to…

Genomics · Quantitative Biology 2025-01-09 Lucas Czech , Moises Exposito-Alonso

The recent progress in DNA sequencing will probably revolutionize the world of electronic. Hence, we went from DNA sequencing that only research centers could realize, to portable, tiny and inexpensive tools. So, it is likely that in a few…

Cryptography and Security · Computer Science 2016-06-22 Amadou Moctar Kane

Privacy-preserving computation (PPC) methods, such as secure multiparty computation (MPC) and homomorphic encryption (HE), are deployed increasingly often to guarantee data confidentiality in computations over private, distributed data.…

Cryptography and Security · Computer Science 2024-04-17 Tariq Bontekoe , Dimka Karastoyanova , Fatih Turkmen

Recent advancements in generative AI have made it possible to create synthetic datasets that can be as accurate as real-world data for training AI models, powering statistical insights, and fostering collaboration with sensitive datasets…

Machine Learning · Computer Science 2025-01-08 Amy Steier , Lipika Ramaswamy , Andre Manoel , Alexa Haushalter

Homomorphic encryption, secure multi-party computation, and differential privacy are part of an emerging class of Privacy Enhancing Technologies which share a common promise: to preserve privacy whilst also obtaining the benefits of…

Human-Computer Interaction · Computer Science 2021-01-21 Nitin Agrawal , Reuben Binns , Max Van Kleek , Kim Laine , Nigel Shadbolt

Motivation: Cutting the cost of DNA sequencing technology led to a quantum leap in the availability of genomic data. While sharing genomic data across researchers is an essential driver of advances in health and biomedical research, the…

Genomics · Quantitative Biology 2022-01-03 Nour Almadhoun Alserr , Ozgur Ulusoy , Erman Ayday , Onur Mutlu

The last few years have seen rapid progress in transitioning quantum computing from lab to industry. In healthcare and life sciences, more than 40 proof-of-concept experiments and studies have been conducted; an increasing number of these…

Quantitative Methods · Quantitative Biology 2025-03-24 Frederik F. Flöther