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We optimized designs of permanent magnet systems to study the effect of magnetic nanoparticles on cell cultures in microslide channels. This produced two designs, one of which is based on a large cylindrical magnet that applies a uniform…

Biological Physics · Physics 2024-01-04 Leon Abelmann , Eunheui Gwag , Baeckkyoung Sung

Drug delivery devices based on nanocomposite membranes containing thermoresponsive nanogels and superparamagnetic nanoparticles have been demonstrated to provide reversible, on-off drug release upon application (and removal) of an…

Magnetotactic bacteria (MTB) are endowed with an exquisite orientation mechanism allowing them to swim along the geomagnetic field lines. This mechanism consists of a chain of bio-synthesized magnetic nano-crystals that endow MTB with a…

The effect of self-generated tension in the backbone of a bottle-brush (BB) macromolecule, adsorbed on an attractive surface, is studied by means of Molecular Dynamics simulations of a coarse-grained bead-spring model in the good solvent…

Soft Condensed Matter · Physics 2015-06-03 J. Paturej , L. Kuban , A. Milchev , T. A. Vilgis

Ordering nanoparticles into a desired super-structure is often crucial for their technological applications. We use molecular dynamics simulations to study the assembly of nanoparticles in a polymer brush randomly grafted to a planar…

Soft Condensed Matter · Physics 2017-12-11 Shengfeng Cheng , Mark J. Stevens , Gary S. Grest

Magnetic particle spectroscopy (MPS) is a technology that derives from magnetic particle imaging (MPI) and thrives as a standalone platform for many biological and biomedical applications, benefiting from the facile preparation and chemical…

Applied Physics · Physics 2020-03-24 Kai Wu , Jinming Liu , Diqing Su , Renata Saha , Vinit Kumar Chugh , Jian-Ping Wang

Colloids self-assemble into various organized superstructures determined by particle interactions. There is a tremendous progress in both the scientific understanding and applications of self-assemblies of single-type identical particles.…

Soft Condensed Matter · Physics 2016-09-23 Chenhui Peng , Taras Turiv , Yubing Guo , Sergij V. Shiyanovskii , Qi-Huo Wei , Oleg D. Lavrentovich

Materials made from active, living, or robotic components can display emergent properties arising from local sensing and computation. Here, we realize a freestanding active metabeam with piezoelectric elements and electronic feed-forward…

Applied Physics · Physics 2021-10-14 Yangyang Chen , Xiaopeng Li , Colin Scheibner , Vincenzo Vitelli , Guoliang Huang

Magnetotaxis is a well known phenomenon in swimming microorganisms which sense magnetic fields e.g. by incorporating crystalline magnetosomes. In designing artificial active matter with tunable dynamics, external magnetic fields can provide…

We combine colloidal self-assembly and soft-lithography techniques to realize flexible magnetic microcrosses that can be manipulated via external, time dependent magnetic fields. The crosses are characterized by a central domain connected…

Soft Condensed Matter · Physics 2025-11-19 Joseph Tavacoli , Andris P. Stikuts , Mihir Dass , Tim Liedl , Pietro Tierno

Understanding the on-chip motion of magnetic particles in a microfluidic environment is key to realizing magnetic particle-based Lab-on-a-chip systems for medical diagnostics. In this work, a simulation model is established to quantify the…

Most microorganisms use hair-like cilia with asymmetric beating to perform vital bio-physical processes. In this paper, we demonstrate a novel fabrication method for creating magnetic artificial cilia capable of such biologically inspired…

Biological Physics · Physics 2018-06-13 Srinivas Hanasoge , Matthew Ballard , Peter J. Hesketh , Alexander Alexeev

This paper introduces the methodology proposed by our group to model the biological soft tissues deformations and to couple these models with Computer-Assisted Surgical (CAS) applications. After designing CAS protocols that mainly focused…

The bipolar organization of the microtubule-based mitotic spindle is essential for the faithful segregation of chromosomes in cell division. Despite our extensive knowledge of genes and proteins, the physical mechanism of how the ensemble…

Biological Physics · Physics 2022-11-02 Lucan Yan , Tatsuya Fukuyama , Megumi Yamaoka , Yusuke T. Maeda , Yuta Shimamoto

The study of the interactions of living adherent cells with mechanically stable (visco)elastic materials enables understanding and exploiting physiological phenomena mediated by cell-extracellular communication. However, insight on the…

We propose a two-dimensional model for the organization of stabilized microtubules driven by molecular motors in an unconfined geometry. In this model two kinds of dynamics are competing. The first one is purely diffusive, with an…

Statistical Mechanics · Physics 2019-08-17 B. Bassetti , M. Cosentino Lagomarsino , P. Jona

Biomedical applications such as targeted drug delivery, microsurgery, and sensing rely on reaching precise areas within the body in a minimally invasive way. Artificial bacterial flagella (ABFs) have emerged as potential tools for this task…

Biological Physics · Physics 2025-05-15 Lucas Amoudruz , Sergey Litvinov , Petros Koumoutsakos

Magnetic nanoflowers (MNFs), which exhibit large intrinsic magnetic losses and high specific absorption rates under clinically relevant alternating magnetic fields, highlight strong potential as efficient mediators for magnetic…

Biomaterials are becoming an essential tool in the study and application of stem cell research. Various types of biomaterials enable three-dimensional (3D) culture of stem cells, and, more recently, also enable high-resolution patterning…

Tissues and Organs · Quantitative Biology 2016-10-11 Richard J. McMurtrey

In simulations, particles are traditionally treated as rigid platforms with variable sizes, shapes and interaction parameters. While this representation is applicable for rigid core platforms, particles consisting of soft platforms (e.g.…

Soft Condensed Matter · Physics 2024-08-06 Massimiliano Paesani , Ioana M. Ilie
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