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Statistical systems are conceived from the standpoint of statistical mechanics, as made of a (generally large) number of identical units and exhibiting a (generally large) number of different configurations (microstates), among which only…

General Physics · Physics 2017-06-21 R. Caimmi

Using German forest health monitoring data we investigate the main drivers leading to tree mortality and the association between defoliation and mortality; in particular (a) whether defoliation is a proxy for other covariates (climate,…

The time evolution of the thermally activated decay rates is considered. This evolution is of particular importance for the recent nanoscale experiments discussed in the literature, where the potential barrier is relatively low (or the…

Statistical Mechanics · Physics 2021-04-21 Maria Chushnyakova , Igor Gontchar , Natalya Khmyrova

Author's early work on aging is developed to yield a relationship between life spans and the velocity of aging. The mathematical analysis shows that the mean extent of the advancement of aging throughout one's life is conserved, or…

Populations and Evolution · Quantitative Biology 2007-05-23 Kazumi Suematsu

The limitations resulting from the dichtomisation of continuous outcomes have been extensively described. But the need to present results based on binary outcomes in particular in health science remains. Alternatives based on the…

Methodology · Statistics 2025-01-15 Odile Sauzet

Although species longevity is subject to a diverse range of selective forces, the mortality curves of a wide variety of organisms are rather similar. We argue that aging and its universal characteristics may have evolved by means of a…

Populations and Evolution · Quantitative Biology 2013-02-01 Dervis Can Vural , Greg Morrison , L. Mahadevan

The number of people able to end Earth's technical civilization has heretofore been small. Emerging dual-use technologies, such as biotechnology, may give similar power to thousands or millions of individuals. To quantitatively investigate…

Popular Physics · Physics 2019-08-15 John G. Sotos

The gradual accumulation of damage and dysregulation during the aging of living organisms can be quantified. Even so, the aging process is complex and has multiple interacting physiological scales -- from the molecular to cellular to whole…

Quantitative Methods · Quantitative Biology 2021-05-06 Spencer Farrell , Garrett Stubbings , Kenneth Rockwood , Arnold Mitnitski , Andrew Rutenberg

In the past six decades, lifespan inequality has varied greatly within and among countries even while life expectancy has continued to increase. How and why does mortality change generate this diversity? We derive a precise link between…

Populations and Evolution · Quantitative Biology 2013-11-22 Duncan O. S. Gillespie , Meredith V. Trotter , Shripad D. Tuljapurkar

Methods for predicting the probability and timing of a species' extinction are typically based on a combination of theoretical models and empirical data, and focus on single species population dynamics. Of course, species also interact with…

Populations and Evolution · Quantitative Biology 2012-06-11 Gian Marco Palamara , Gustav W. Delius , Matthew J. Smith , Owen L. Petchey

Dynamical phenomena such as infectious diseases are often investigated by following up subjects longitudinally, thus generating time to event data. The spatial aspect of such data is also of primordial importance, as many infectious…

Methodology · Statistics 2020-10-13 Ajmal Oodally , Estelle Kuhn , Klara Goethals , Luc Duchateau

Living systems are subject to the arrow of time; from birth, they undergo complex transformations (self-organization) in a constant battle for survival, but inevitably ageing and disease trap them to death. Can ageing be understood and…

Other Quantitative Biology · Quantitative Biology 2020-08-21 Tamàs Fülöp , Mathieu Desroches , Fernando Antônio Nóbrega Santos , Serafim Rodrigues

To describe the nonequilibrium states of a system we introduce a new thermodynamic parameter - the lifetime (the first passage time) of a system. The statistical distributions that can be obtained out of the mesoscopic description…

Chemical Physics · Physics 2007-05-23 V. V. Ryazanov

The population size has far-reaching effects on the fitness of the population, that, in its turn influences the population extinction or persistence. Understanding the density- and age-dependent factors will facilitate more accurate…

Dynamical Systems · Mathematics 2021-02-12 Jonathan Andersson , Vladimir Kozlov , Vladimir G. Tkachev , Sonja Radosavljevic , Uno Wennergren

The question of whether biological populations survive or are eventually driven to extinction has long been examined using mathematical models. In this work we study population survival or extinction using a stochastic, discrete…

Populations and Evolution · Quantitative Biology 2021-09-15 Yifei Li , Stuart T. Johnston , Pascal R. Buenzli , Peter van Heijster , Matthew J. Simpson

\noindent The modal age at death is an increasingly used measure for understanding longevity and mortality patterns. However, existing estimation methods focus on point estimates, overlooking the inherent variability and uncertainty in…

Applications · Statistics 2025-10-07 Silvio C. Patricio , Paola Vazquez-Castillo

We introduce and investigate the escape problem for random walkers that may eventually die, decay, bleach, or lose activity during their diffusion towards an escape or reactive region on the boundary of a confining domain. In the case of a…

Chemical Physics · Physics 2020-01-03 D. S. Grebenkov , J. -F. Rupprecht

Several independent observations have suggested that catastrophe transition in microtubules is not a first-order process, as is usually assumed. Recent {\it in vitro} observations by Gardner et al.[ M. K. Gardner et al., Cell {\bf147}, 1092…

Subcellular Processes · Quantitative Biology 2015-07-02 V. Jemseena , Manoj Gopalakrishnan

The study considers the model of an abstract organism, called Arbitrary Oscillator (ArbO), which is capable of making decisions at each timed step. These decisions are 'critical' since, randomly, their outcome can be 'fatal' for ArbO, thus…

Physics and Society · Physics 2026-01-07 Giuseppe Alberti

The far-from-equilibrium dynamics of glassy systems share important phenomenological traits. A transition is generally observed from a time-homogeneous dynamical regime to an aging regime where physical changes occur intermittently and, on…

Soft Condensed Matter · Physics 2015-03-13 S. Boettcher , P. Sibani