English
Related papers

Related papers: Coding Sequence Density Estimation Via Topological…

200 papers

We have presented the basic knowledge on the structure of molecules coding the genetic information, mechanisms of transfer of this information from DNA to proteins and phenomena connected with replication of DNA. In particular, we have…

Genomics · Quantitative Biology 2009-09-30 Dorota Mackiewicz , Stanislaw Cebrat

Phenomenological (P-type) bifurcations are qualitative changes in stochastic dynamical systems whereby the stationary probability density function (PDF) changes its topology. The current state of the art for detecting these bifurcations…

Algebraic Topology · Mathematics 2024-06-10 Sunia Tanweer , Firas A. Khasawneh

Toxicity prediction of chemical compounds is a grand challenge. Lately, it achieved significant progress in accuracy but using a huge set of features, implementing a complex blackbox technique such as a deep neural network, and exploiting…

Machine Learning · Computer Science 2019-01-29 Abdul Karim , Avinash Mishra , M A Hakim Newton , Abdul Sattar

This paper constructs individual-specific density forecasts for a panel of firms or households using a dynamic linear model with common and heterogeneous coefficients as well as cross-sectional heteroskedasticity. The panel considered in…

Econometrics · Economics 2021-10-06 Laura Liu

Conditional density estimation (CDE) goes beyond regression by modeling the full conditional distribution, providing a richer understanding of the data than just the conditional mean in regression. This makes CDE particularly useful in…

Machine Learning · Computer Science 2024-10-16 Lincen Yang , Matthijs van Leeuwen

This paper presents a probabilistic approach for DNA sequence analysis. A DNA sequence consists of an arrangement of the four nucleotides A, C, T and G and different representation schemes are presented according to a probability measure…

Quantitative Methods · Quantitative Biology 2010-02-12 Amrita Priyam , B. M. Karan , G. Sahoo

Current state-of-the-art methods for automatic synthetic speech evaluation are based on MOS prediction neural models. Such MOS prediction models include MOSNet and LDNet that use spectral features as input, and SSL-MOS that relies on a…

Establishing associations between the structure and the generalisation ability of deep neural networks (DNNs) is a challenging task in modern machine learning. Producing solutions to this challenge will bring progress both in the…

Machine Learning · Computer Science 2020-05-01 Mehmet Süzen , J. J. Cerdà , Cornelius Weber

A measure called Physical Complexity is established and calculated for a population of sequences, based on statistical physics, automata theory, and information theory. It is a measure of the quantity of information in an organism's genome.…

Biological Physics · Physics 2011-12-02 Gerard Briscoe , Philippe De Wilde

Chronic obstructive pulmonary disease (COPD) is a lung disease which can be quantified using chest computed tomography (CT) scans. Recent studies have shown that COPD can be automatically diagnosed using weakly supervised learning of…

Computer Vision and Pattern Recognition · Computer Science 2017-11-27 Veronika Cheplygina , Isabel Pino Peña , Jesper Holst Pedersen , David A. Lynch , Lauge Sørensen , Marleen de Bruijne

In this paper, we propose a dictionary screening method for embedding compression in text classification tasks. The key purpose of this method is to evaluate the importance of each keyword in the dictionary. To this end, we first train a…

Computation and Language · Computer Science 2022-11-24 Jing Zhou , Xinru Jing , Muyu Liu , Hansheng Wang

Nervous systems are characterized by neurons displaying a diversity of morphological shapes. Traditionally, different shapes have been qualitatively described based on visual inspection and quantitatively described based on morphometric…

Neurons and Cognition · Quantitative Biology 2016-03-29 Lida Kanari , Paweł Dłotko , Martina Scolamiero , Ran Levi , Julian Shillcock , Kathryn Hess , Henry Markram

The vast majority of the neural network literature focuses on predicting point values for a given set of response variables, conditioned on a feature vector. In many cases we need to model the full joint conditional distribution over the…

Machine Learning · Statistics 2016-06-09 Wesley Tansey , Karl Pichotta , James G. Scott

Recent work suggests that some auto-encoder variants do a good job of capturing the local manifold structure of the unknown data generating density. This paper contributes to the mathematical understanding of this phenomenon and helps…

Machine Learning · Computer Science 2012-07-03 Yoshua Bengio , Guillaume Alain , Salah Rifai

In drug discovery, it is vital to confirm the predictions of pharmaceutical properties from computational models using costly wet-lab experiments. Hence, obtaining reliable uncertainty estimates is crucial for prioritizing drug molecules…

Machine Learning · Computer Science 2023-10-19 Siddhartha Laghuvarapu , Zhen Lin , Jimeng Sun

When training transformers on graph-structured data, incorporating information about the underlying topology is crucial for good performance. Topological masking, a type of relative position encoding, achieves this by upweighting or…

We measure the three-dimensional topology of large-scale structure in the Sloan Digital Sky Survey (SDSS). This allows the genus statistic to be measured with unprecedented statistical accuracy. The sample size is now sufficiently large to…

Data analysis in high-dimensional spaces aims at obtaining a synthetic description of a data set, revealing its main structure and its salient features. We here introduce an approach providing this description in the form of a topography of…

Machine Learning · Statistics 2021-03-02 Maria d'Errico , Elena Facco , Alessandro Laio , Alex Rodriguez

Abstract: In this article, we will analyze in detail the coding limit of an individual sequence by introducing the latest developments brought by the Set Shaping Theory. This new theory made us realize that there is a huge difference…

Information Theory · Computer Science 2023-05-09 Aida Koch , Alix Petit

Modern sequence to sequence neural TTS systems provide close to natural speech quality. Such systems usually comprise a network converting linguistic/phonetic features sequence to an acoustic features sequence, cascaded with a neural…

Audio and Speech Processing · Electrical Eng. & Systems 2019-09-26 Slava Shechtman , Alex Sorin