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We address the problem of building theoretical models that help elucidate the function of the visual brain at computational/algorithmic and structural/mechanistic levels. We seek to understand how the receptive fields and topographic maps…

Neural and Evolutionary Computing · Computer Science 2020-11-10 Simon Osindero

Far from being a passive information store, the genome is a mechanically dynamic and diverse system in which torsion and tension fluctuate and combine to determine structure and help regulate gene expression. Much of this mechanical…

Biomolecules · Quantitative Biology 2021-09-01 Jack W Shepherd , Mark C Leake

Describing a complex system is in many ways a problem akin to identifying an object, in that it involves defining boundaries, constituent parts and their relationships by the use of grouping laws. Here we propose a novel method which…

Many complex networks, ranging from social to biological systems, exhibit structural patterns consistent with an underlying hyperbolic geometry. Revealing the dimensionality of this latent space can disentangle the structural complexity of…

We propose a light-weight deep convolutional neural network (CNN) to estimate the cosmological parameters from simulated 3-dimensional dark matter distributions with high accuracy. The training set is based on 465 realizations of a cubic…

Cosmology and Nongalactic Astrophysics · Physics 2020-06-11 Shuyang Pan , Miaoxin Liu , Jaime Forero-Romero , Cristiano G. Sabiu , Zhigang Li , Haitao Miao , Xiao-Dong Li

We explore the possibility of retrieving cosmological information from 21-cm tomographic data at intermediate redshift. The first step in our approach consists of training an encoder, composed of several three dimensional convolutional…

Instrumentation and Methods for Astrophysics · Physics 2025-07-30 Sambatra Andrianomena

Prediction and discovery of new materials with desired properties are at the forefront of quantum science and technology research. A major bottleneck in this field is the computational resources and time complexity related to finding new…

Discrete speech representation learning has recently attracted increasing interest in both acoustic and semantic modeling. Existing approaches typically encode 16 kHz waveforms into discrete tokens at a rate of 25 or 50 tokens per second.…

Computation and Language · Computer Science 2025-09-03 Jialong Zuo , Guangyan Zhang , Minghui Fang , Shengpeng Ji , Xiaoqi Jiao , Jingyu Li , Yiwen Guo , Zhou Zhao

We propose a measure based upon the fundamental theoretical concept in algorithmic information theory that provides a natural approach to the problem of evaluating $n$-dimensional complexity by using an $n$-dimensional deterministic Turing…

Computational Complexity · Computer Science 2015-08-27 Hector Zenil , Fernando Soler-Toscano , Jean-Paul Delahaye , Nicolas Gauvrit

We introduce \emph{topological density estimation} (TDE), in which the multimodal structure of a probability density function is topologically inferred and subsequently used to perform bandwidth selection for kernel density estimation. We…

Methodology · Statistics 2022-03-10 Steve Huntsman

Probabilistic embeddings have several advantages over deterministic embeddings as they map each data point to a distribution, which better describes the uncertainty and complexity of data. Many works focus on adjusting the distribution…

Artificial Intelligence · Computer Science 2024-12-16 Xiang Huang , Hao Peng , Li Sun , Hui Lin , Chunyang Liu , Jiang Cao , Philip S. Yu

We use Topological Data Analysis tools for studying the inner organization of cells in segmented images of epithelial tissues. More specifically, for each segmented image, we compute different persistence barcodes, which codify lifetime of…

Computer Vision and Pattern Recognition · Computer Science 2022-04-11 N. Atienza , M. J. Jimenez , M. Soriano-Trigueros

The understanding of toxicity is of paramount importance to human health and environmental protection. Quantitative toxicity analysis has become a new standard in the field. This work introduces element specific persistent homology (ESPH),…

Quantitative Methods · Quantitative Biology 2017-12-13 Kedi Wu , Guo-Wei Wei

We investigate a densely packed, non-random arrangement of forty-six chromosomes (46,XY) in human nuclei. Here, we model systems-level chromosomal crosstalk by unifying intrinsic parameters (chromosomal length and number of genes) across…

Genomics · Quantitative Biology 2017-11-09 Sarosh N. Fatakia , Ishita S. Mehta , Basuthkar J. Rao

The constraint of neighborhood consistency or local consistency is widely used for robust image matching. In this paper, we focus on learning neighborhood topology consistent descriptors (TCDesc), while former works of learning descriptors,…

Computer Vision and Pattern Recognition · Computer Science 2020-09-16 Honghu Pan , Fanyang Meng , Nana Fan , Zhenyu He

Convolutional Neural Networks (CNN) have recently been demonstrated on synthetic data to improve upon the precision of cosmological inference. In particular they have the potential to yield more precise cosmological constraints from weak…

Cosmology and Nongalactic Astrophysics · Physics 2019-09-17 Janis Fluri , Tomasz Kacprzak , Aurelien Lucchi , Alexandre Refregier , Adam Amara , Thomas Hofmann , Aurel Schneider

Developing quantitative methods for characterizing structural properties of force chains in densely packed granular media is an important step toward understanding or predicting large-scale physical properties of a packing. A promising…

Soft Condensed Matter · Physics 2016-10-05 Chad Giusti , Lia Papadopoulos , Eli T. Owens , Karen E. Daniels , Danielle S. Bassett

In the human genomes, recombination frequency between homologous chromosomes during meiosis is highly correlated with their physical length while it differs significantly when their coding density is considered. Furthermore, it has been…

Populations and Evolution · Quantitative Biology 2010-02-01 Dorota Mackiewicz , Marta Zawierta , Wojciech Waga , Stanislaw Cebrat

Topological features based on persistent homology capture high-order structural information so as to augment graph neural network methods. However, computing extended persistent homology summaries remains slow for large and dense graphs and…

Machine Learning · Computer Science 2022-11-16 Zuoyu Yan , Tengfei Ma , Liangcai Gao , Zhi Tang , Yusu Wang , Chao Chen

Predictive Coding (PC) is a theoretical framework in cognitive science suggesting that the human brain processes cognition through spatiotemporal prediction of the visual world. Existing studies have developed spatiotemporal prediction…

Neural and Evolutionary Computing · Computer Science 2024-05-07 Kaiyuan Chen , Xingzhuo Guo , Yu Zhang , Jianmin Wang , Mingsheng Long