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Spontaneous symmetry breaking plays a pivotal role in physics ranging from the emergence of elementary particles to the phase transitions of matter. The spontaneous breaking of continuous time translation symmetry leads to a novel state of…

An RNA sequence is a string composed of four types of nucleotides, $A, C, G$, and $U$. The goal of the RNA folding problem is to find a maximum cardinality set of crossing-free pairs of the form $\{A,U\}$ or $\{C,G\}$ in a given RNA…

Computational Complexity · Computer Science 2018-03-23 Yi-Jun Chang

Super cooled liquids display increasingly heterogeneous dynamics as temperature is lowered towards the glass transition ($T_{g}$). A hallmark of this dynamical heterogeneity is the spontaneous emergence of cooperative rearranging regions…

Soft Condensed Matter · Physics 2021-12-16 Dipanwita Ghoshal , Ashwin Joy

RNA molecules are single-stranded analogues of DNA that can fold into various structures which influence their biological function within the cell. RNA structures can be modelled combinatorially in terms of a certain type of graph called an…

Combinatorics · Mathematics 2022-04-14 Vincent Moulton , Taoyang Wu

An $k$-noncrossing RNA structure can be identified with an $k$-noncrossing diagram over $[n]$, which in turn corresponds to a vacillating tableaux having at most $(k-1)$ rows. In this paper we derive the limit distribution of irreducible…

Biomolecules · Quantitative Biology 2009-02-24 Emma Y. Jin , Christian M. Reidys

We report simulations on the homogeneous liquid-fcc nucleation of charged colloids for both low and high contact energy values. As a precursor for crystal formation, we observe increased local order at the position where the crystal will…

Soft Condensed Matter · Physics 2014-11-03 Kai Kratzer , Axel Arnold

Protein folding cooperativity is defined by the nature of the finite-size thermodynamic transition exhibited upon folding: two-state transitions show a free energy barrier between the folded and unfolded ensembles, while downhill folding is…

Biomolecules · Quantitative Biology 2017-08-23 Tristan Bereau , Michael Bachmann , Markus Deserno

We study the phase structure of QCD at high temperature and density by lattice QCD simulations adopting a histogram method. The quark mass dependence and the chemical potential dependence of the nature of phase transition are investigated…

High Energy Physics - Lattice · Physics 2013-07-25 Shinji Ejiri

Inspired by complete graph theory, we demonstrate that a metallic claw "meta-atom" structure can carry a high number of nearly degenerate resonant modes. A photonic meta-crystal composing of a lattice of such meta-atoms exhibits a large…

Classical Physics · Physics 2019-11-06 Hanyu Wang , Biao Yang , Wei Xu , Yuancheng Fan , Qinghua Guo , Zhihong Zhu , C. T. Chan

We analyze the ways in which the random first order phase transition (RFOT) of the glass transition differs from the well-studied regular first order and second order (or continuous) phase transitions. Just as is the case in the latter two…

Statistical Mechanics · Physics 2024-09-23 T. R. Kirkpatrick , D. Thirumalai

The routine transformation of a liquid, as it is cooled rapidly, resulting in glass formation, is remarkably complex. A theoretical explanation of the dynamics associated with this process has remained one of the major unsolved problems in…

Disordered Systems and Neural Networks · Physics 2014-12-17 T. R. Kirkpatrick , D. Thirumalai

We characterize the low temperature phase of a simple model for RNA secondary structures by determining the typical energy scale E(l) of excitations involving l bases. At zero temperature, we find a scaling law E(l) \sim l^\theta with…

Statistical Mechanics · Physics 2009-11-07 F. Krzakala , M. Mezard , M. Mueller

We re-examine a population model which exhibits a continuous absorbing phase transition which belongs to directed percolation in 1+1 dimensions and a first order transition in 2+1 dimensions and above. Studying the model on fractal…

Statistical Mechanics · Physics 2015-05-13 Alastair L Windus , Henrik Jeldtoft Jensen

We re-examine the evolutionary dynamics of RNA secondary structures under directional selection towards an optimum RNA structure. We find that the punctuated equilibria lead to a very slow approach to the optimum, following on average an…

Populations and Evolution · Quantitative Biology 2010-11-05 P. Sulc , A. Wagner , O. C. Martin

A phase separation in a spatially heterogeneous environment is closely related to intracellular science and material science. For the phase separation, initial heterogeneous perturbations play an important role in pattern formations. In…

Statistical Mechanics · Physics 2024-08-30 Rikuya Ishikawa , Rei Kurita

In these lectures, I review cosmological phase transitions and the topological aspects of spontaneous symmetry breaking. I then discuss the formation of walls, strings and monopoles during phase transitions including lattice based studies…

High Energy Physics - Phenomenology · Physics 2007-05-23 Tanmay Vachaspati

The tertiary structures of functional RNA molecules remain difficult to decipher. A new generation of automated RNA structure prediction methods may help address these challenges but have not yet been experimentally validated. Here we apply…

Biomolecules · Quantitative Biology 2011-10-05 Wipapat Kladwang , Fang-Chieh Chou , Rhiju Das

The present paper is devoted to the study of the combinatorics of 216 maximal $C^3$ circular codes --- a particular type of structure arising in the analysis of genomic sequences. Their circularity property is believed to be intimately…

Combinatorics · Mathematics 2018-05-15 Aleksandr Serdiukov , Andrei Smolensky

We describe the critical window for percolation in the universality class of sparse growing random graphs. In our models, vertices arrive sequentially and connect independently to each earlier vertex $v$ with probability proportional to a…

Probability · Mathematics 2025-12-23 Joost Jorritsma , Pascal Maillard , Peter Mörters

Based on the Monte Carlo kinetic method, we investigated the formation mechanisms of periodical modulations arising along the length of one-dimensional structures. The evolution of initially cylindrical nanowires/slabs at temperatures lower…

Mesoscale and Nanoscale Physics · Physics 2021-02-17 Vyacheslav N. Gorshkov , Vladimir V. Tereshchuk , Pooya Sareh