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The phase diagram of superconducting copper oxides is calculated as a function of doping based on a theory of dynamic stripe induced superconductivity. The two major conclusions from the theory and the numerical analysis are that T* (the…

In this work we propose a physical model of organismal evolution, where phenotype, organism life expectancy, is directly related to genotype i.e. the stability of its proteins which can be determined exactly in the model. Simulating the…

Populations and Evolution · Quantitative Biology 2007-05-23 Konstantin B. Zeldovich , Boris E. Shakhnovich , Eugene I. Shakhnovich

The evolution of particulate and multiphase systems can transition from dynamic regimes, governed by classical transport equations with well-defined damping coefficients, to anomalously slow relaxation described by rate equations when the…

Soft Condensed Matter · Physics 2025-08-20 Carlos E. Colosqui

We report that protein confinement within nanoscopic vesicular compartments corresponds to a liquid-liquid phase transition with the protein/water within vesicle lumen interacting very differently than in bulk. We show this effect leads to…

Recent observations of the growth of protein crystals have identified two different growth regimes. At low supersaturation, the surface of the crystal is smooth and increasing in size due to the nucleation of steps at defects and the…

Soft Condensed Matter · Physics 2015-05-14 James F. Lutsko , Vasileios Basios , Gregoire Nicolis , John J. Kozak , Mike Sleutel , Dominique Maes

A systematic solution of a general model for Copper-Oxides reveals a line of transitions $T = T_p (x)$ for $x$, the doping away from half-filling less than a critical value, to a phase with broken time reversal and rotational symmetry but…

Condensed Matter · Physics 2009-09-25 C. M. Varma

Phase transitions are fundamental features of statistical physics. While the well-studied continuous phase transitions are known to be controlled by external \textit{macroscopic} changes in the order parameter, the origin of abrupt…

Physics and Society · Physics 2024-10-25 Bnaya Gross , Irina Volotsenko , Yuval Sallem , Nahala Yadid , Ivan Bonamassa , Shlomo Havlin , Aviad Frydman

We investigate theoretically the behavior of proteins as well as other large macromolecules which are incorporated into amphiphilic monolayers at the air-water interface. We assume the monolayer to be in the coexistence region of the…

Soft Condensed Matter · Physics 2007-05-23 R. R. Netz , D. Andelman , H. Orland

We study an active random walker model in which a particle's motion is determined by a self-generated field. The field encodes information about the particle's path history. This leads to either self-attractive or self-repelling behavior.…

Statistical Mechanics · Physics 2009-11-11 R. Grima

We investigate strong-coupling properties of a two-dimensional ultracold Fermi gas in the normal phase. In the three-dimensional case, it has been shown that the so-called pseudogap phenomena can be well described by a (non-self-consistent)…

Quantum Gases · Physics 2016-10-31 Morio Matsumoto , Ryo Hanai , Daisuke Inotani , Yoji Ohashi

Despite significant progress in static protein structure collection and prediction, the dynamic behavior of proteins, one of their most vital characteristics, has been largely overlooked in prior research. This oversight can be attributed…

Biomolecules · Quantitative Biology 2024-09-19 Ce Liu , Jun Wang , Zhiqiang Cai , Yingxu Wang , Huizhen Kuang , Kaihui Cheng , Liwei Zhang , Qingkun Su , Yining Tang , Fenglei Cao , Limei Han , Siyu Zhu , Yuan Qi

Lipid rafts are heterogeneous dynamic lipid domains of the cell membranes that are involved in several biological processes, like protein and lipids specific transport and signaling. Our understanding of lipid raft formation is still…

We explain the physical basis of a model for small globular proteins with water interactions. The water is supposed to access the protein interior in an "all-or-none" manner during the unfolding of the protein chain. As a consequence of…

Condensed Matter · Physics 2009-10-31 Audun Bakk , Alex Hansen , Kim Sneppen

Prediction of protein-ligand binding affinity is a major goal in drug discovery. Generally, free energy gap is calculated between two states (e.g., ligand binding and unbinding). The energy gap implicitly includes the effects of changes in…

Biomolecules · Quantitative Biology 2022-05-20 Ikki Yasuda , Katsuhiro Endo , Eiji Yamamoto , Yoshinori Hirano , Kenji Yasuoka

We report on a study of the electromagnetic response of three different families of high-T_c superconductors that in combination allowed us to cover the whole doping range from under- to overdoped. The discussion is focused on the ab-plane…

Superconductivity · Physics 2008-02-03 A. V. Puchkov , D. N. Basov , T. Timusk

We provide evidence that the energy landscapes of folded proteins do not shift with temperature, but the onset of functional dynamics is associated with its effective sampling. The motion of the backbone is described by three distinct…

Soft Condensed Matter · Physics 2007-05-23 Canan Baysal , Ali Rana Atilgan

Protein conformational changes are activated processes essential for protein functions. Activation in a protein differs from activation in a small molecule in that it involves directed and systematic energy flows through preferred channels…

Biological Physics · Physics 2020-07-15 Huiyu Li , Ao Ma

A new formulation of statistical mechanics is put forward according to which a random variable characterizing a macroscopic body is postulated to be infinitely divisible. It leads to a parametric representation of partition function of an…

Mathematical Physics · Physics 2008-11-06 E. D. Belokolos

We investigate the transition of a quantum wave-packet through a one-dimensional avoided crossing of molecular energy levels when the energy levels at the crossing point are tilted. Using superadiabatic representations, and an approximation…

Mathematical Physics · Physics 2010-07-16 Volker Betz , Benjamin D. Goddard

We use computer simulations to study the microscopic dynamics of an athermal assembly of soft particles near the fluid-to-solid, jamming transition. Borrowing tools developed to study dynamic heterogeneity near glass transitions, we…

Materials Science · Physics 2010-06-24 Claus Heussinger , Ludovic Berthier , Jean-Louis Barrat