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We investigate proteins within heterogeneous cell membranes where non-equilibrium phenomena arises from spatial variations in concentration and temperature. We develop simulation methods building on non-equilibrium statistical mechanics to…

Soft Condensed Matter · Physics 2025-08-28 D. Jasuja , P. J. Atzberger

Self Consistent Normal Mode Analysis (SCNMA) is applied to heme c type cytochrome f to study temperature dependent protein motion. Classical Normal Mode Analysis (NMA) assumes harmonic behavior and the protein Mean Square Displacement (MSD)…

Biological Physics · Physics 2013-05-29 Jianguang Guo , Timo Budarz , Joshua M. Ward , Earl W. Prohofsky

Motor proteins are active enzyme molecules that play a crucial role in many biological processes. They transform the chemical energy into the mechanical work and move unidirectionally along rigid cytoskeleton filaments. Single-molecule…

Soft Condensed Matter · Physics 2009-11-13 Rahul Kumar Das , Anatoly B. Kolomeisky

An adiabatic transition between two equilibrium states corresponding to different stiffnesses in an infinite chain of particles is studied. Initially, the chain particles have random displacements and random velocities corresponding to a…

Statistical Mechanics · Physics 2020-11-04 Anton M. Krivtsov , Andrey S. Murachev

We study the dynamics of a molecule's nuclear wave-function near an avoided crossing of two electronic energy levels, for one nuclear degree of freedom. We derive the general form of the Schroedinger equation in the n-th superadiabatic…

Mathematical Physics · Physics 2015-05-13 Volker Betz , Benjamin D. Goddard , Stefan Teufel

This article reviews the current status of precursor superconducting phase fluctuations as a possible mechanism for pseudogap formation in high-temperature superconductors. In particular we compare this approach which relies on the…

Superconductivity · Physics 2007-05-23 Vadim M. Loktev , Rachel M. Quick , Sergei G. Sharapov

The relationship between the pseudogap and superconductivity remains a central puzzle in the physics of cuprates. Hydrostatic pressure provides a clean tuning parameter free from chemical disorder, yet probing the microscopic energy scales…

Many physical systems, including classical fluids, present in their phase diagram the competition between two phases that are separated by a line of first-order phase transitions which terminates at a so-called critical point. Despite…

High Energy Physics - Theory · Physics 2025-04-29 Zi-Qiang Zhao , Zhang-Yu Nie , Jing-Fei Zhang , Xin Zhang , Matteo Baggioli

We describe the approach of the superconducting state as a sequence of cross-over phenomena. As the temperature is decreased, uncorrelated pairing of the electrons leads to the opening of a pseudogap at T_F^*. Upon further lowering the…

Superconductivity · Physics 2009-10-31 P. Devillard , J. Ranninger

One of the most remarkable properties of the high-temperature superconductors is a pseudogap regime appearing in the underdoped cuprates above the superconducting transition temperature T_c. The pseudogap continously develops out of the…

Superconductivity · Physics 2009-11-10 T. Eckl , W. Hanke , S. V. Borisenko , A. A. Kordyuk , T. Kim , A. Koitzsch , M. Knupfer , J. Fink

Superionic phase transitions have attracted extensive interest for decades due to their promising applications and rich underlying physics. In particular, complicated many-body effects and nonadiabatic dynamics are believed to play…

Materials Science · Physics 2026-04-02 Jiaming Hu , Zhichao Guo , Jingyi Liang , Bartomeu Monserrat

A phase transition indicates a sudden change in the properties of a large system. For temperature-driven phase transitions this is related to non-analytic behavior of the free energy density at the critical temperature: The knowledge of the…

Statistical Mechanics · Physics 2015-03-20 Markus Heyl , Anatoli Polkovnikov , Stefan Kehrein

Mean square displacements of hydrogen atoms in glass-forming materials and proteins, as reported by incoherent elastic neutron scattering, show kinks in their temperature dependence. This crossover, known as the dynamical transition,…

Soft Condensed Matter · Physics 2016-08-24 Salman Seyedi , Daniel R. Martin , Dmitry V. Matyushov

Biomolecular folding, at least in simple systems, can be described as a two state transition in a free energy landscape with two deep wells separated by a high barrier. Transition paths are the short part of the trajectories that cross the…

Statistical Mechanics · Physics 2018-12-10 M. Laleman , E. Carlon , H. Orland

A central goal of protein-folding theory is to predict the stochastic dynamics of transition paths --- the rare trajectories that transit between the folded and unfolded ensembles --- using only thermodynamic information, such as a…

Biomolecules · Quantitative Biology 2018-08-09 William M. Jacobs , Eugene I. Shakhnovich

Analyses of experimental data in the literature show thresholds that directly imply a coexistent superconductive (SC) and pseudogap (PG) phase that, to our knowledge, has not been previously identified. The data used emphasize the essences…

Superconductivity · Physics 2025-03-25 K. E. Gray

Stochastic dynamics of chemical reactions in a mutually repressing two-gene circuit is numerically simulated. The circuit has a rich variety of different states when the kinetic change of DNA status is slow. The stochastic switching…

Disordered Systems and Neural Networks · Physics 2009-11-11 Tomohiro Ushikubo , Wataru Inoue , Mitsumasa Yoda , Masaki Sasai

Underdoped cuprate superconductors are believed to be strongly correlated with electronic systems with small phase stiffness leading to a large phase fluctuation region is known as the pseudogap state. With increasing doping it is generally…

Superconductivity · Physics 2025-07-03 Hércules H. Santana and , E. V. L. de Mello

The internal dynamics of strongly interacting systems and that of biomolecules such as proteins display several important analogies, despite the huge difference in their characteristic energy and length scales. For example, in all such…

Biological Physics · Physics 2015-05-30 Pietro Faccioli

In this study, we introduced a new unit, named "protein token", as a dynamic protein structural unit for protein-protein interactions. Unlike the conventional structural units, protein token is not based on the sequential or spatial…

Biomolecules · Quantitative Biology 2018-09-28 Si-Wei Luo , Yi-Hua Jiang , Zhi Liang , Jia-Rui Wu
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