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We study the long-time behaviour of a run and tumble model which is a kinetic-transport equation describing bacterial movement under the effect of a chemical stimulus. The experiments suggest that the non-uniform tumbling kernels are…

Analysis of PDEs · Mathematics 2024-04-30 Josephine Evans , Havva Yoldaş

Efficient nutrient mixing is crucial for the survival of bacterial colonies and other living systems. This raises the question of whether the optimization of mixing through the emergence of active turbulent motion in bacterial swarms played…

Soft Condensed Matter · Physics 2022-09-27 Rodrigo C. V. Coelho , Nuno A. M. Araújo , Margarida M. Telo da Gama

We study the chemotaxis of a population of genetically identical swimming bacteria undergoing run and tumble dynamics driven by stochastic switching between clockwise and counterclockwise rotation of the flagellar rotary system.…

Cell Behavior · Quantitative Biology 2020-07-17 Margaritis Voliotis , Jerko Rosko , Teuta Pilizota , Tanniemola Liverpool

Although the motility of the flagellated bacteria, Escherichia coli, has been widely studied, the effect of viscosity on swimming speed remains controversial. The swimming mode of wild-type E.coli is often idealized as a "run-and- tumble"…

Biological Physics · Physics 2018-05-09 Zijie Qu , Fatma Zeynep Temel , Rene Henderikx , Kenneth S. Breuer

We discuss velocity-jump models for chemotaxis of bacteria with an internal state that allows the velocity jump rate to depend on the memory of the chemoattractant concentration along their path of motion. Using probabilistic techniques, we…

Numerical Analysis · Mathematics 2011-11-23 Mathias Rousset , Giovanni Samaey

Bacteria can chemotactically migrate up attractant gradients by controlling run-and-tumble motility patterns. In addition to this well-known chemotactic behaviour, several soil and marine bacterial species perform chemokinesis: they adjust…

Biological Physics · Physics 2021-03-19 Theresa Jakuszeit , James Lindsey-Jones , François J. Peaudecerf , Ottavio A. Croze

Intracellular components explore the cytoplasm via active motor-driven transport in conjunction with passive diffusion. We model the motion of organelles in narrow tubular cells using analytical techniques and numerical simulations to study…

Biological Physics · Physics 2018-04-11 Saurabh Mogre , Elena F. Koslover

Bacteria typically reside in heterogeneous environments with various chemogradients where motile cells can gain an advantage over non-motile cells. Since motility is energetically costly, cells must optimize their swimming speed and…

Populations and Evolution · Quantitative Biology 2020-05-05 Gurdip Uppal , Weiyi Hu , Dervis Can Vural

Communication and coordination play a major role in the ability of bacterial cells to adapt to ever changing environments and conditions. Recent work has shown that such coordination underlies several aspects of bacterial responses…

Quantitative Methods · Quantitative Biology 2016-04-12 Shashank Singh , Sabrina Rashid , Zhicheng Long , Saket Navlakha , Hanna Salman , Zoltan N. Oltvai , Ziv Bar-Joseph

Biomolecular motors use free energy to drive a variety of cellular tasks, including the transport of cargo, such as vesicles and organelles. We find that the widely-used `constant-force' approximation for the effect of cargo on motor…

Statistical Mechanics · Physics 2023-04-11 Aidan I Brown , David A Sivak

A trophallaxis inspired model for distributed transport between randomly interacting agents Trophallaxis, the regurgitation and mouth to mouth transfer of liquid food between members of eusocial insect societies, is an important process…

Biological Physics · Physics 2017-08-16 Johannes Gräwer , Henrik Ronellenfitsch , Marco G. Mazza , Eleni Katifori

We introduce a generic, purely mechanical model for environment sensitive motion of mammalian cells that is applicable to chemotaxis, haptotaxis, and durotaxis as modes of motility. It is able to theoretically explain all relevant…

Cell Behavior · Quantitative Biology 2016-05-09 Patrick Bitter , Kristof Leon Beck , Peter Lenz

We use the mean-bacterial-velocity model to investigate the \textit{irreversibility} of two-dimensional (2D) \textit{bacterial turbulence} and to compare it with its 2D fluid-turbulence counterpart. We carry out extensive direct numerical…

Fluid Dynamics · Physics 2022-02-01 Kolluru Venkata Kiran , Anupam Gupta , Akhilesh Kumar Verma and , Rahul Pandit

Diverse processes--e.g. bioremediation, biofertilization, and microbial drug delivery--rely on bacterial migration in disordered, three-dimensional (3D) porous media. However, how pore-scale confinement alters bacterial motility is unknown…

Soft Condensed Matter · Physics 2019-05-09 Tapomoy Bhattacharjee , Sujit S. Datta

The effect of mechanical interactions between cells in the spreading of bacterial populations was investigated in one-dimensional space. A continuum-mechanics approach, comprising cell migration, proliferation, and exclusion processes, was…

Biological Physics · Physics 2015-12-15 Waipot Ngamsaad , Suthep Suantai

This paper is devoted to the justification of the macroscopic, mean-field nutrient taxis system with doubly degenerate cross-diffusion proposed by Leyva et al. (2013) to model the complex spatio-temporal dynamics exhibited by the bacterium…

Analysis of PDEs · Mathematics 2017-11-09 Ramon G. Plaza

The more we learn about the cytoplasm of cells, the more we realise that the cytoplasm is not uniform but instead is highly inhomogeneous. In any inhomogeneous solution, there are concentration gradients, and particles move either up or…

Subcellular Processes · Quantitative Biology 2019-04-03 Richard P. Sear

Chemotactic active particles, such as bacteria and cells, exhibit an adaptive run-and-tumble motion, giving rise to complex emergent behaviors in response to external chemical fields. This motion is generated by the conversion of internal…

Soft Condensed Matter · Physics 2024-02-06 Minh D. N. Nguyen , Phuc H. Pham , Khang V. Ngo , Van H. Do , Shengkai Li , Trung V. Phan

We study colonies of non-motile, rod-shaped bacteria growing on solid substrates. In our model, bacteria interact purely mechanically, by pushing each other away as they grow, and consume a diffusing nutrient. We show that mechanical…

Biological Physics · Physics 2015-06-15 F. D. C. Farrell , O. Hallatschek , D. Marenduzzo , B. Waclaw

The large-scale collective behavior of biological systems can be characterized by macroscopic transport, which arises from the non-equilibrium microscopic interactions among individual constituents. A prominent example is the formation of…

Statistical Mechanics · Physics 2025-07-29 Subhadip Chakraborti , Vasily Zaburdaev