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Model-based treatment planning for transcranial ultrasound therapy typically involves mapping the acoustic properties of the skull from an x-ray computed tomography (CT) image of the head. Here, three methods for generating pseudo-CT images…

Computational fluid dynamics (CFD) can be used for evaluation of hemodynamics. However, its routine use is limited by labor-intensive manual segmentation, CFD mesh creation, and time-consuming simulation. This study aims to train a deep…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Tina Yao , Endrit Pajaziti , Michael Quail , Silvia Schievano , Jennifer A Steeden , Vivek Muthurangu

We implemented a fast Reciprocal Monte Carlo algorithm, to accurately solve radiative heat transfer in turbulent flows of non-grey participating media that can be coupled to fully resolved turbulent flows, namely to Direct Numerical…

Computational Engineering, Finance, and Science · Computer Science 2019-05-21 Simone Silvestri , Rene Pecnik

Computed Tomography (CT) is a vital diagnostic tool in clinical practice, yet the health risks associated with ionizing radiation cannot be overlooked. Low-dose CT (LDCT) helps mitigate radiation exposure but simultaneously leads to reduced…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Guoliang Gong , Man Yu

With X-ray radiation protection and dose management constantly gaining interest in interventional radiology, novel procedures often undergo prospective dose studies using anthropomorphic phantoms to determine expected dose values. Due to…

Recently, deep learning (DL) found its way to interventional X-ray skin dose estimation. While its performance was found to be acceptable, even more accurate results could be achieved if more data sets were available for training. One…

Background: Recently, the popularity of dual-layer flat-panel detector (DL-FPD) based dual-energy cone-beam CT (DE-CBCT) imaging has been increasing. However, the image quality of DE-CBCT remains constrained by the Compton scattered X-ray…

CBCT images suffer from acute shading artifacts primarily due to scatter. Numerous image-domain correction algorithms have been proposed in the literature that use patient-specific planning CT images to estimate shading contributions in…

Computer Vision and Pattern Recognition · Computer Science 2018-01-18 Awais Ashfaq , Jonas Adler

$Objective$. Obtaining the intrinsic dose distributions in particle therapy is a challenging problem that needs to be addressed by imaging algorithms to take advantage of secondary particle detectors. In this work, we investigate the…

Instrumentation and Detectors · Physics 2022-09-28 Atiq. Ur. Rahman , Mythra Varun. Nemallapudi , Cheng-Ying. Chou , Shih-Chang Lee , Chih-Hsun. Lin

Four-dimensional Cone Beam Computed Tomography (4D-CBCT) has been developed to provide respiratory phase resolved volumetric imaging in image guided radiation therapy (IGRT). Inadequate number of projections in each phase bin results in low…

Medical Physics · Physics 2015-06-03 Xun Jia , Zhen Tian , Yifei Lou , Jan-Jakob Sonke , Steve B. Jiang

A proton pencil beam is associated with a surrounding low-dose envelope, originating from nuclear interactions. It is important for treatment planning systems to accurately model this envelope when performing dose calculations for pencil…

Medical Physics · Physics 2015-11-30 David C. Hall , Anastasia Makarova , Harald Paganetti , Bernard Gottschalk

Accurate 3D dose calculation for Pencil Beam Scanning Proton Therapy (PBSPT) is typically performed with Monte Carlo (MC) engines, but their runtimes limit adaptive workflows and repeated evaluations. Current deep-learning proton dose…

Medical Physics · Physics 2026-02-19 Mikołaj Stryja , Danny Lathouwers , Zoltán Perkó

Monte Carlo (MC) methods provide the most accurate to-date dose calculations in heterogeneous media and complex geometries, and this spawns increasing interest in incorporating MC calculations into treatment planning quality assurance…

Medical Physics · Physics 2009-01-07 C. Locke , S. Zavgorodni

Purpose: We presented a GPU-based MC framework, ARCHER-EPID, specifically designed for EPID transit dosimetry, with improving accuracy and efficiency. Methods: A comprehensive MC framework was developed to perform full radiation transport…

Medical Physics · Physics 2025-10-29 Ning Gao , Didi Li , Na Liu , Yankui Chang , Qiang Ren , Xi Pei , Zhi Wang , Xie George Xu

We discuss the efficiency of Monte Carlo methods in solving continuum radiative transfer problems. The sampling of the radiation field and convergence of dust temperature calculations in the case of optically thick clouds are both studied.…

Astrophysics · Physics 2009-11-10 M. Juvela

Particle therapy is an established method to treat deep-seated tumours using accelerator-produced ion beams. For treatment planning, the precise knowledge of the relative stopping power (RSP) within the patient is vital. Conversion errors…

Background: Treatment verification with PET imaging in charged particle therapy is conventionally done by comparing measurements of spatial distributions with Monte Carlo (MC) predictions. However, decay curves can provide additional…

Recently we have developed an algorithm for reconstructing volumetric images and extracting 3D tumor motion information from a single x-ray projection. We have demonstrated its feasibility using a digital respiratory phantom with regular…

In this work, we proposed virtual imaging simulators as an alternative approach to experimental validation of beam range uncertainty in complex patient geometry using a computational model of a human head and a photon-counting CT scanner.…

Medical Physics · Physics 2026-01-05 S. Vrbaški , G. Stanić , S. Molinelli , M. Bhattarai , E. Abadi , M. Ciocca , E. Samei