Related papers: Non-equilibrium phase transitions in biomolecular …
One of the fundamental cellular processes governed by genetic regulatory networks in cells is the transition among different states under the intrinsic and extrinsic noise. Based on a two-state genetic switching model with positive…
Noise-induced switching between coexisting metastable states occurs in a wide range of far-from-equilibrium systems including micro-mechanical oscillators, epidemiological and climate change models, and nonlinear electronic transport in…
We consider the dynamics of a population of organisms containing two mutually inhibitory gene regulatory networks, that can result in a bistable switch-like behaviour. We completely characterize their local and global dynamics in the…
Non-reciprocal interactions are prevalent in various complex systems leading to phenomena that cannot be described by traditional equilibrium statistical physics. Although non-reciprocally interacting systems composed of two populations…
Quasiparticles are an important decoherence mechanism in superconducting qubits, and can be described with a complex admittance that is a generalization of the Mattis-Bardeen theory. By injecting non-equilibrium quasiparticles with a tunnel…
We determine the steady-state phases of a driven-dissipative Bose-Hubbard model, describing, e.g., an array of coherently pumped nonlinear cavities with a finite photon lifetime. Within a mean-field master equation approach using exact…
A central challenge in physics is to describe non-equilibrium systems driven by randomness, such as a randomly growing interface, or fluids subject to random fluctuations that account e.g. for local stresses and heat fluxes not related to…
We propose a general theory to describe the distribution of protein-folding transition paths. We show that transition paths follow a predictable sequence of high-free-energy transient states that are separated by free-energy barriers. Each…
Multistable gene regulatory systems sustain different levels of gene expression under identical external conditions. Such multistability is used to encode phenotypic states in processes including nutrient uptake and persistence in bacteria,…
Systems with nonreciprocal interactions generically display time-dependent states. These are routinely observed in finite systems, from neuroscience to active matter, in which globally ordered oscillations exist. However, the stability of…
Noise caused by fluctuations at the molecular level is a fundamental part of intracellular processes. While the response of biological systems to noise has been studied extensively, there has been limited understanding of how to exploit it…
We obtain the steady-state phase diagram of a transverse field XY spin chain coupled at its ends to magnetic reservoirs held at different magnetic potentials. In the long-time limit, the magnetization bias across the system generates a…
An important task in quantitative biology is to understand the role of stochasticity in biochemical regulation. Here, as an extension of our recent work [Phys. Rev. Lett. 107, 148101 (2011)], we study how input fluctuations affect the…
The microscopic model in which nodes interacting with each other are statistical systems is introduced. The nodes conditions are connected with a string of distinct microscopic configurations and depend on external parameters (pressure and…
Just as transition rates in a canonical ensemble must respect the principle of detailed balance, constraints exist on transition rates in driven steady states. I derive those constraints, by maximum information-entropy inference, and apply…
A switched equilibrium of a switched system of two subsystems is a such a point where the vector fields of the two subsystems point strictly towards one another. Using the concept of stable convex combination that was developed by…
Biological molecular machines are proteins that operate under isothermal conditions hence are referred to as free energy transducers. They can be formally considered as enzymes that simultaneously catalyze two chemical reactions: the free…
Phase transitions in equilibrium and nonequilibrium systems play a major role in the natural sciences. In dynamical networks, phase transitions organize qualitative changes in the collective behavior of coupled dynamical units. Adaptive…
Scaling ideas and renormalization group approaches proved crucial for a deep understanding and classification of critical phenomena in thermal equilibrium. Over the past decades, these powerful conceptual and mathematical tools were…
Many processes in chemistry, physics, and biology involve rare events in which the system escapes from a metastable state by surmounting an activation barrier. Examples range from chemical reactions, protein folding, and nucleation events…