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We present Meraculous2, an update to the Meraculous short-read assembler that includes (1) handling of allelic variation using "bubble" structures within the de Bruijn graph, (2) improved gap closing, and (3) an improved scaffolding…

Data Structures and Algorithms · Computer Science 2017-11-09 Jarrod A. Chapman , Isaac Y. Ho , Eugene Goltsman , Daniel S. Rokhsar

We introduce a parallel algorithmic architecture for metagenomic sequence assembly, termed MetaPar, which allows for significant reductions in assembly time and consequently enables the processing of large genomic datasets on computers with…

Quantitative Methods · Quantitative Biology 2013-11-18 Minji Kim , Jonathan G. Ligo , Amin Emad , Farzad Farnoud , Olgica Milenkovic , Venugopal V. Veeravalli

Sparse matrix-matrix multiplication (SpGEMM) is a widely used kernel in various graph, scientific computing and machine learning algorithms. In this paper, we consider SpGEMMs performed on hundreds of thousands of processors generating…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-10-19 Md Taufique Hussain , Oguz Selvitopi , Aydin Buluç , Ariful Azad

Graphs are a powerful tool for analyzing large data sets, but many real-world phenomena involve interactions that go beyond the simple pairwise relationships captured by a graph. In this paper we introduce and study a simple combinatorial…

Data Structures and Algorithms · Computer Science 2025-11-25 Elise Tate , Joshua A. Grochow

We present SparseAttnNet, a new hierarchical attention-driven framework for efficient image classification that adaptively selects and processes only the most informative pixels from images. Traditional convolutional neural networks…

Image and Video Processing · Electrical Eng. & Systems 2025-05-13 Elad Yoshai , Dana Yagoda-Aharoni , Eden Dotan , Natan T. Shaked

Human visual recognition is a sparse process, where only a few salient visual cues are attended to rather than traversing every detail uniformly. However, most current vision networks follow a dense paradigm, processing every single visual…

Computer Vision and Pattern Recognition · Computer Science 2023-04-10 Ziteng Gao , Zhan Tong , Limin Wang , Mike Zheng Shou

Graph clustering or community detection constitutes an important task for investigating the internal structure of graphs, with a plethora of applications in several domains. Traditional techniques for graph clustering, such as spectral…

Graphs are useful to interpret widely used image processing methods, e.g., bilateral filtering, or to develop new ones, e.g., kernel based techniques. However, simple graph constructions are often used, where edge weight and connectivity…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Sarath Shekkizhar , Antonio Ortega

Image enhancement approaches often assume that the noise is signal independent, and approximate the degradation model as zero-mean additive Gaussian. However, this assumption does not hold for biomedical imaging systems where sensor-based…

Image and Video Processing · Electrical Eng. & Systems 2023-04-10 Calvin-Khang Ta , Abhishek Aich , Akash Gupta , Amit K. Roy-Chowdhury

Graph Neural Networks (GNNs) have achieved significant improvements in various domains. Sparse Matrix-Matrix multiplication (SpMM) is a fundamental operator in GNNs, which performs a multiplication between a sparse matrix and a dense…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-07-08 Guyue Huang , Guohao Dai , Yu Wang , Huazhong Yang

Genome sequence analysis plays a pivotal role in enabling many medical and scientific advancements in personalized medicine, outbreak tracing, and forensics. However, the analysis of genome sequencing data is currently bottlenecked by the…

Hardware Architecture · Computer Science 2021-11-04 Damla Senol Cali

Signal modeling lies at the core of numerous signal and image processing applications. A recent approach that has drawn considerable attention is sparse representation modeling, in which the signal is assumed to be generated as a…

Information Theory · Computer Science 2016-11-17 Tomer Peleg , Yonina C. Eldar , Michael Elad

Haplotype-resolved de novo assembly is the ultimate solution to the study of sequence variations in a genome. However, existing algorithms either collapse heterozygous alleles into one consensus copy or fail to cleanly separate the…

Genomics · Quantitative Biology 2021-02-03 Haoyu Cheng , Gregory T Concepcion , Xiaowen Feng , Haowen Zhang , Heng Li

A primary challenge in metagenomics is reconstructing individual microbial genomes from the mixture of short fragments created by sequencing. Recent work leverages the sparsity of the assembly graph to find $r$-dominating sets which enable…

Data Structures and Algorithms · Computer Science 2023-01-24 Yosuke Mizutani , Annie Staker , Blair D. Sullivan

The formation trajectory planning using complete graphs to model collaborative constraints becomes computationally intractable as the number of drones increases due to the curse of dimensionality. To tackle this issue, this paper presents a…

Robotics · Computer Science 2024-03-27 Yuan Zhou , Lun Quan , Chao Xu , Guangtong Xu , Fei Gao

Adapter Tuning, which freezes the pretrained language models (PLMs) and only fine-tunes a few extra modules, becomes an appealing efficient alternative to the full model fine-tuning. Although computationally efficient, the recent Adapters…

Computation and Language · Computer Science 2022-11-11 Shwai He , Liang Ding , Daize Dong , Miao Zhang , Dacheng Tao

We present SparseGen, a novel framework for efficient image-to-3D generation, which exhibits low input-view bias while being significantly faster. Unlike traditional approaches that rely on dense volumetric grids, triplanes, or…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Zhiyuan Xu , Jiuming Liu , Yuxin Chen , Masayoshi Tomizuka , Chenfeng Xu , Chensheng Peng

In big data image/video analytics, we encounter the problem of learning an overcomplete dictionary for sparse representation from a large training dataset, which can not be processed at once because of storage and computational constraints.…

Machine Learning · Computer Science 2014-03-20 Subhadip Mukherjee , Chandra Sekhar Seelamantula

Since convolutional neural networks perform well in learning generalizable image priors from large-scale data, these models have been widely used in image denoising tasks. However, the computational complexity increases dramatically as well…

Image and Video Processing · Electrical Eng. & Systems 2022-07-29 Yuanfan Zhang , Gen Li , Lei Sun

We propose a novel two-stage framework of generative models named Debiasing Kernel-Based Generative Models (DKGM) with the insights from kernel density estimation (KDE) and stochastic approximation. In the first stage of DKGM, we employ KDE…

Machine Learning · Statistics 2025-03-31 Tian Qin , Wei-Min Huang