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A basic task in bioinformatics is the counting of $k$-mers in genome strings. The $k$-mer counting problem is to build a histogram of all substrings of length $k$ in a given genome sequence. We present the open source $k$-mer counting…

Data Structures and Algorithms · Computer Science 2016-07-25 Marius Erbert , Steffen Rechner , Matthias Müller-Hannemann

Error correction of sequenced reads remains a difficult task, especially in single-cell sequencing projects with extremely non-uniform coverage. While existing error correction tools designed for standard (multi-cell) sequencing data…

Quantitative Methods · Quantitative Biology 2013-01-31 Sergey I. Nikolenko , Anton I. Korobeynikov , Max A. Alekseyev

We present scalable distributed-memory algorithms for sparse matrix permutation, extraction, and assignment. Our methods follow an Identify-Exchange-Build (IEB) strategy where each process identifies the local nonzeros to be sent, exchanges…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-26 Elaheh Hassani , Md Taufique Hussain , Ariful Azad

Subgraph matching is a fundamental problem in graph analysis with a wide range of applications. However, due to its inherent NP-hardness, enumerating subgraph matches efficiently on large real-world graphs remains highly challenging. Most…

Databases · Computer Science 2026-03-11 Linglin Yang , Xunbin Su , Lei Zou , Xiangyang Gou , Yinnian Lin

Exploring and detecting community structures hold significant importance in genetics, social sciences, neuroscience, and finance. Especially in graphical models, community detection can encourage the exploration of sets of variables with…

Machine Learning · Statistics 2024-05-17 Dapeng Shi , Tiandong Wang , Zhiliang Ying

Existing 3D algorithms for distributed-memory sparse kernels suffer from limited scalability due to reliance on bulk sparsity-agnostic communication. While easier to use, sparsity-agnostic communication leads to unnecessary bandwidth and…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-05-01 Nabil Abubaker , Torsten Hoefler

We propose Sparse Sinkhorn Attention, a new efficient and sparse method for learning to attend. Our method is based on differentiable sorting of internal representations. Concretely, we introduce a meta sorting network that learns to…

Machine Learning · Computer Science 2020-02-27 Yi Tay , Dara Bahri , Liu Yang , Donald Metzler , Da-Cheng Juan

Sliding window sums are widely used in bioinformatics applications, including sequence assembly, k-mer generation, hashing and compression. New vector algorithms which utilize the advanced vector extension (AVX) instructions available on…

Data Structures and Algorithms · Computer Science 2019-09-04 Roman Snytsar , Yatish Turakhia

Sparse tensors are prevalent in real-world applications, often characterized by their large-scale, high-order, and high-dimensional nature. Directly handling raw tensors is impractical due to the significant memory and computational…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-05-24 Zixuan Li , Mingxing Duan , Huizhang Luo , Wangdong Yang , Kenli Li , Keqin Li

Accelerated MRI involves collecting partial $k$-space measurements to reduce acquisition time, patient discomfort, and motion artifacts, and typically uses regular undersampling patterns or human-designed schemes. Recent works have studied…

Image and Video Processing · Electrical Eng. & Systems 2026-05-20 Siddhant Gautam , Angqi Li , Nicole Seiberlich , Jeffrey A. Fessler , Saiprasad Ravishankar

We propose a novel, structured pruning algorithm for neural networks -- the iterative, Sparse Structured Pruning algorithm, dubbed as i-SpaSP. Inspired by ideas from sparse signal recovery, i-SpaSP operates by iteratively identifying a…

Machine Learning · Computer Science 2022-03-31 Cameron R. Wolfe , Anastasios Kyrillidis

Deep neural networks (DNNs) have been proven to be effective in solving many real-life problems, but its high computation cost prohibits those models from being deployed to edge devices. Pruning, as a method to introduce zeros to model…

Machine Learning · Computer Science 2021-12-22 Fei Sun , Minghai Qin , Tianyun Zhang , Xiaolong Ma , Haoran Li , Junwen Luo , Zihao Zhao , Yen-Kuang Chen , Yuan Xie

Multiplication of a sparse matrix to a dense matrix (SpDM) is widely used in many areas like scientific computing and machine learning. However, existing works under-look the performance optimization of SpDM on modern many-core…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-06-01 Shaohuai Shi , Qiang Wang , Xiaowen Chu

The repeat content and heterozygosity rate of a target genome are important factors in determining the feasibility of achieving a complete telomere-to-telomere assembly. The mathematical relationship between the required coverage and read…

Information Theory · Computer Science 2025-04-08 Daanish Mahajan , Chirag Jain , Navin Kashyap

We propose a sparse grids based adaptive noise reduction strategy for electrostatic particle-in-cell (PIC) simulations. Our approach is based on the key idea of relying on sparse grids instead of a regular grid in order to increase the…

Sparse graph recovery methods work well where the data follows their assumptions but often they are not designed for doing downstream probabilistic queries. This limits their adoption to only identifying connections among the input…

Machine Learning · Computer Science 2024-10-23 Harsh Shrivastava , Urszula Chajewska

Due to the significant computational challenge of training large-scale graph neural networks (GNNs), various sparse learning techniques have been exploited to reduce memory and storage costs. Examples include \textit{graph sparsification}…

Machine Learning · Computer Science 2023-02-07 Shuai Zhang , Meng Wang , Pin-Yu Chen , Sijia Liu , Songtao Lu , Miao Liu

Clustering analysis has been widely used in trust evaluation on various complex networks such as wireless sensors networks and online social networks. Spectral clustering is one of the most commonly used algorithms for graph-structured data…

Social and Information Networks · Computer Science 2021-12-03 Gang Mei , Jingzhi Tu , Lei Xiao , Francesco Piccialli

Recently, crossbar array based in-memory accelerators have been gaining interest due to their high throughput and energy efficiency. While software and compiler support for the in-memory accelerators has also been introduced, they are…

Hardware Architecture · Computer Science 2025-01-14 Jihoon Park , Jeongin Choe , Dohyun Kim , Jae-Joon Kim

Compressed Sensing MRI reconstructs images of the body's internal anatomy from undersampled measurements, thereby reducing scan time. Recently, deep learning has shown great potential for reconstructing high-fidelity images from highly…

Image and Video Processing · Electrical Eng. & Systems 2025-04-07 Armeet Singh Jatyani , Jiayun Wang , Aditi Chandrashekar , Zihui Wu , Miguel Liu-Schiaffini , Bahareh Tolooshams , Anima Anandkumar
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