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New lensless diffractive X-ray technic for micro-scale imaging of biological tissue is based on quantitative phase retrieval schemes. By incorporating refraction, this method yields improved contrast compared to purely absorption-based…

Numerical Analysis · Mathematics 2018-03-28 Victor Palamodov

X-ray diffraction tomography (XDT) resolves spatially-variant XRD profiles within macroscopic objects, and provides improved material contrast compared to the conventional transmission-based computed tomography (CT). However, due to the…

Medical Physics · Physics 2019-01-04 Zheyuan Zhu , Alexander Katsevich , Shuo Pang

Photon counting detection is a promising approach toward effectively reducing the radiation dose in x-ray computed tomography (CT). Full CT reconstruction from a fraction of the detected photons required by scintillation-based detectors has…

Medical Physics · Physics 2020-08-24 Zheyuan Zhu , Hsin-Hsiung Huang , Shuo Pang

Biological soft tissues encountered in clinical and pre-clinical imaging mainly consist of light element atoms, and their composition is nearly uniform with little density variation. Thus, x-ray attenuation imaging suffers from low image…

Medical Physics · Physics 2011-06-28 Wenxiang Cong , Atsushi Momose , Ge Wang

The aim of this research is to reconstruct the 3D X-ray refractive index gradient maps by the proposed vector Radon transform and its inverse, assuming that the small-angle deviation condition is met. Theoretical analyses show that the…

Medical Physics · Physics 2023-09-20 Keliang Liao , Qili He , Panyun Li , Liang Luo , Peiping Zhu

Interior tomography for the region-of-interest (ROI) imaging has advantages of using a small detector and reducing X-ray radiation dose. However, standard analytic reconstruction suffers from severe cupping artifacts due to existence of…

Computer Vision and Pattern Recognition · Computer Science 2018-01-04 Yoseob Han , Jawook Gu , Jong Chul Ye

Region-of-Interest (ROI) tomography aims at reconstructing a region of interest $C$ inside a body using only x-ray projections intersecting $C$ with the goal to reduce overall radiation exposure when only a small specific region of the body…

Mathematical Physics · Physics 2016-03-23 Robert Azencott , Bernhard G. Bodmann , Tasadduk Chowdhury , Demetrio Labate , Anando Sen , Daniel Vera

Interior tomography is a typical strategy for radiation dose reduction in computed tomography, where only a certain region-of-interest (ROI) is scanned. However, given the truncated projection data, ROI reconstruction by conventional…

Medical Physics · Physics 2022-09-22 Changyu Chen , Yuxiang Xing , Li Zhang , Zhiqiang Chen

In this paper, we develop a novel phase retrieval approach to reconstruct x-ray differential phase shift induced by an object. A primary advantage of our approach is a higher-order accuracy over that with the conventional linear…

Medical Physics · Physics 2010-03-18 Wenxiang Cong , Ge Wang

Computed tomography for region-of-interest (ROI) reconstruction has advantages of reducing X-ray radiation dose and using a small detector. However, standard analytic reconstruction methods suffer from severe cupping artifacts, and existing…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Yoseob Han , Jong Chul Ye

X-Ray Phase-Contrast Imaging (PCI) yields absorption, differential phase, and dark-field images. Computed Tomography (CT) of grating-based PCI can in principle provide high-resolution soft-tissue contrast. Recently, grating-based PCI took…

Optical diffraction tomography (ODT) provides three-dimensional refractive index (RI) tomograms of a transparent microscopic object. However, because of the finite numerical aperture of objective lenses, ODT has the limited access to…

Optics · Physics 2017-11-22 Moosung Lee , Seungwoo Shin , YongKeun Park

This work introduces a novel reinterpretation of structured illumination (SI) microscopy for coherent imaging that allows three-dimensional imaging of complex refractive index (RI). To do so, we show that coherent SI is mathematically…

Optics · Physics 2017-05-11 Shwetadwip Chowdhury , Will J. Eldridge , Adam Wax , Joseph A. Izatt

Coherent diffraction imaging (CDI) for visualizing objects at atomic resolution has been realized as a promising tool for imaging single molecules. Drawbacks of CDI are associated with the difficulty of the numerical phase retrieval from…

We introduce a single-frame diffractive imaging method called randomized probe imaging (RPI). In RPI, a sample is illuminated by a structured probe field containing speckles smaller than the sample's typical feature size. Quantitative…

We present a tomographic imaging technique, termed Deep Prior Diffraction Tomography (DP-DT), to reconstruct the 3D refractive index (RI) of thick biological samples at high resolution from a sequence of low-resolution images collected…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Kevin C. Zhou , Roarke Horstmeyer

Phase retrieval, or the process of recovering phase information in reciprocal space to reconstruct images from measured intensity alone, is the underlying basis to a variety of imaging applications including coherent diffraction imaging…

Computer Vision and Pattern Recognition · Computer Science 2018-11-15 Mathew J. Cherukara , Youssef S. G. Nashed , Ross J. Harder

Refractive Index Tomography is the inverse problem of reconstructing the continuously-varying 3D refractive index in a scene using 2D projected image measurements. Although a purely refractive field is not directly visible, it bends light…

Computer Vision and Pattern Recognition · Computer Science 2023-12-06 Brandon Zhao , Aviad Levis , Liam Connor , Pratul P. Srinivasan , Katherine L. Bouman

In coherent X-ray diffraction microscopy the diffraction pattern generated by a sample illuminated with coherent x-rays is recorded, and a computer algorithm recovers the unmeasured phases to synthesize an image. By avoiding the use of a…

We proposed a novel approach to coherent imaging of dynamic samples. The inter-frame similarity of the sample's local structures is found to be a powerful constraint in phasing a sequence of diffraction patterns. We devised a new image…

Optics · Physics 2024-07-11 Pengju Sheng , Fucai Zhang
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