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Ab initio molecular dynamics simulations of liquid water under equilibrium ambient conditions, together with a novel energy decomposition analysis, have recently shown that a substantial fraction of water molecules exhibit a significant…

Disordered Systems and Neural Networks · Physics 2020-06-24 Hossam Elgabarty , Thomas D. Kühne

Isothermal-isobaric molecular dynamics simulations are used to examine the microscopic structure and some properties of water-methanol liquid mixture. The TIP4P/2005 and SPC/E water models are combined with the united atom TraPPE and the…

Soft Condensed Matter · Physics 2019-03-28 M. Cruz Sanchez , H. Dominguez , O. Pizio

Water and water-mediated interactions determine thermodynamic and kinetics of protein folding, protein aggregation and self-assembly in confined spaces. To obtain insights into the role of water in the context of folding problems, we…

Soft Condensed Matter · Physics 2015-05-28 S. Vaitheeswaran , Jie Chen , D. Thirumalai

A large number of water models exists for molecular simulations. They differ in the ability to reproduce specific features of real water instead of others, like the correct temperature for the density maximum or the diffusion coefficient.…

Soft Condensed Matter · Physics 2012-06-04 Roman Shevchuk , Diego Prada-Gracia , Francesco Rao

In this manuscript, we present a general computational method for characterizing the molecular structure of liquid water interfaces as sampled from atomistic simulations. With this method, the interfacial structure is quantified based on…

Soft Condensed Matter · Physics 2017-08-25 Sucheol Shin , Adam P. Willard

A key starting assumption in many classical interatomic potential models for materials is a site energy decomposition of the potential energy surface into contributions that only depend on a small neighbourhood. Under a natural stability…

Mathematical Physics · Physics 2020-09-10 Jack Thomas

We study the potential energy landscape explored during a compression-decompression cycle for the SPC/E (extended simple point charge) model of water. During the cycle, the system changes from low density amorphous ice (LDA) to high density…

Soft Condensed Matter · Physics 2009-11-10 Nicolas Giovambattista , H. Eugene Stanley , Francesco Sciortino

Equations of state for hydrogen bonding fluids are typically described by two energy scales. A short range highly directional hydrogen bond energy scale, as well as a reference energy scale which accounts for dispersion and orientationally…

Soft Condensed Matter · Physics 2016-12-28 Bennett D. Marshall

On a basis of a two-length scale description of hydrophobic interactions we develop a continuous self-consistent theory of solute-water interactions which allows to determine a hydrophobic layer of a solute molecules of any geometry with…

Soft Condensed Matter · Physics 2007-05-23 G. Sitnikov , S. Nechaev , M. Taran , A. Muryshev

Water shapes and defines the properties of biological systems. Therefore, understanding the nature of the mutual interaction between water and biological systems is of primary importance for a proper assessment of biological activity and…

Soft Condensed Matter · Physics 2021-01-18 Fausto Martelli , Carles Calero , Giancarlo Fanzese

Hydrophobic hydration plays a crucial role in self-assembly processes over multiple length-scales, but the extrapolation of molecular-scale models to larger length-scale hydration phenomena is sometimes not warranted. Scaled-particle…

Biological Physics · Physics 2007-05-23 Henry S. Ashbaugh , Lawrence R. Pratt

A new empirical potential for efficient, large scale molecular dynamics simulation of water is presented. The HIPPO (Hydrogen-like Intermolecular Polarizable POtential) force field is based upon the model electron density of a hydrogen-like…

Chemical Physics · Physics 2021-09-30 Joshua A. Rackers , Roseane R. Silva , Zhi Wang , Jay W. Ponder

Liquid water, besides being fundamental for life on Earth, has long fascinated scientists due to several anomalies. Different hypotheses have been put forward to explain these peculiarities. The most accredited one foresees the presence in…

Numerical Analysis · Mathematics 2022-10-26 Michele Benzi , Isabella Daidone , Chiara Faccio , Laura Zanetti-Polzi

The solvation of charged, nanometer-sized spherical solutes in water, and the effective, solvent-induced force between two such solutes are investigated by constant temperature and pressure Molecular Dynamics simulations of model solutes…

Soft Condensed Matter · Physics 2009-11-10 J. Dzubiella , J. -P. Hansen

Machine learning has the potential to revolutionize the field of molecular simulation through the development of efficient and accurate models of interatomic interactions. In particular, neural network models can describe interactions at…

Chemical Physics · Physics 2022-04-06 Ang Gao , Richard C. Remsing

First principles molecular dynamics simulation protocol is established using revised functional of Perdew-Burke-Ernzerhof (revPBE) in conjunction with Grimme's third generation of dispersion (D3) correction to describe properties of water…

Recent measurements of microsphere interactions in diverse media suggest that the standard dielectric-continuum models of solution-phase interactions are fundamentally incomplete. Experiments indicate that the interactions of charged…

Soft Condensed Matter · Physics 2026-05-12 Ali Behjatian , Madhavi Krishnan

This paper reviews the molecular theory of hydrophobic effects relevant to biomolecular structure and assembly in aqueous solution. Recent progress has resulted in simple, validated molecular statistical thermodynamic theories and…

Chemical Physics · Physics 2015-06-26 Lawrence R. Pratt

Dynamic structuring of water is a key player in a large class of processes underlying biochemical and technological developments today, the latter often involving electric fields. However, the anisotropic coupling between the water…

Soft Condensed Matter · Physics 2019-05-29 Andreas Baer , Zoran Miličević , David M. Smith , Ana-Sunčana Smith

Water is an associated liquid in which the main intermolecular interaction is the hydrogen bond (HB) which is limited to four per atom, independently of the number of neighbours. We have considered a hydrogen bond net superposed on Bernal's…

Statistical Mechanics · Physics 2009-11-07 Nara Guisoni , Vera Bohomoletz Henriques