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Many systems in biology, physics and engineering can be described by systems of ordinary differential equation containing many parameters. When studying the dynamic behavior of these large, nonlinear systems, it is useful to identify and…

Molecular Networks · Quantitative Biology 2016-04-13 Heather A. Harrington , Dhagash Mehta , Helen M. Byrne , Jonathan D. Hauenstein

In this paper we study two models for crowd motion and herding. Each of the models is of Keller-Segel type and involves two parabolic equations, one for the evolution of the density and one for the evolution of a mean field potential. We…

Analysis of PDEs · Mathematics 2016-01-20 Jean Dolbeault , Peter Markowich , Gaspard Jankowiak

The methodology named LIFE (Linear-in-Flux-Expressions) was developed with the purpose of simulating and analyzing large metabolic systems. With LIFE, the number of model parameters is reduced by accounting for correlations among the…

Optimization and Control · Mathematics 2019-03-29 Nathaniel J. Merrill , Zheming An , Sean T. McQuade , Federica Garin , Karim Azer , Ruth E. Abrams , Benedetto Piccoli

The Cauchy problem for the parabolic--elliptic Keller--Segel system in the whole $n$-dimensional space is studied. For this model, every constant $A \in \mathbb{R}$ is a stationary solution. The main goal of this work is to show that $A <…

Analysis of PDEs · Mathematics 2021-01-06 Szymon Cygan , Grzegorz Karch , Krzysztof Krawczyk , Hiroshi Wakui

We study the existence and stability of stationary solutions of Poisson-Nernst- Planck equations with steric effects (PNP-steric equations) with two counter-charged species. These equations describe steady current through open ionic…

Analysis of PDEs · Mathematics 2018-01-26 Nir Gavish

Reaction-diffusion equations coupled to ordinary differential equations (ODEs) may exhibit spatially low-regular stationary solutions. This work provides a comprehensive theory of asymptotic stability of bounded, discontinuous or…

Analysis of PDEs · Mathematics 2023-05-18 Chris Kowall , Anna Marciniak-Czochra , Finn Münnich

Coupled Tchebyscheff maps have recently been introduced to explain parameters in the standard model of particle physics, using the stochastic quantisation of Parisi and Wu. This paper studies dynamical properties of these maps, finding…

Chaotic Dynamics · Physics 2025-08-04 Carl P. Dettmann

Applications of stochastic models often involve the evaluation of steady-state performance, which requires solving a set of balance equations. In most cases of interest, the number of equations is infinite or even uncountable. As a result,…

Optimization and Control · Mathematics 2022-04-08 Shukai Li , Sanjay Mehrotra

We show how the stability conditions for a system of interacting fermions that conventionally involve variations of thermodynamic potentials can be rewritten in terms of one- and two-particle correlators. We illustrate the applicability of…

Strongly Correlated Electrons · Physics 2024-08-09 A. Kowalski , M. Reitner , L. Del Re , M. Chatzieleftheriou , A. Amaricci , A. Toschi , L. de' Medici , G. Sangiovanni , T. Schäfer

Several types of stochastic equations are important in thermodynamics, chemistry, evolutionary biology, population dynamics and quantitative social science. For systems with pair interactions four different types of equations are derived,…

Statistical Mechanics · Physics 2009-10-31 Dirk Helbing

In this paper, we establish the existence and instability of standing wave for a system of nonlinear Schr\"{o}dinger equations arising in the two-wave model with quadratic interaction in higher space dimensions under mass resonance…

Analysis of PDEs · Mathematics 2023-07-04 Zaihui Gan , Yue Wang

Fractional derivative and delay are important tools in modeling memory properties in the natural system. This work deals with the stability analysis of a fractional order delay differential equation \begin{equation*} D^\alpha x(t)=\delta…

Dynamical Systems · Mathematics 2022-08-29 Sachin Bhalekar , Deepa Gupta

This paper investigates the dynamics of immune response and autoimmunity with particular emphasis on the role of regulatory T cells (Tregs), T cells with different activation thresholds, and cytokines in mediating T cell activity. Analysis…

Quantitative Methods · Quantitative Biology 2019-05-01 F. Fatehi , Y. N. Kyrychko , R. Molchanov , K. B. Blyuss

We consider weakly interacting diffusions on the torus, for multichromatic interaction potentials. We consider interaction potentials that are not H-stable, leading to phase transitions in the mean field limit. We show that the mean field…

Mathematical Physics · Physics 2025-03-18 Benedetta Bertoli , Benjamin D. Goddard , Grigorios A. Pavliotis

Motivation: Many biochemical pathways are known, but the numerous parameters required to correctly explore the dynamics of the pathways are not known. For this reason, algorithms that can make inferences by looking at the topology of a…

Molecular Networks · Quantitative Biology 2009-07-23 Deepak Chandran , Herbert M. Sauro

We show that a simple experimental setting of a locally pumped and lossy array of two-level quantum systems can stabilize states with strong long-range coherence. Indeed, by explicit analytic construction, we show there is an extensive set…

Quantum Gases · Physics 2020-12-11 Shovan Dutta , Nigel R. Cooper

Communication between cells is realized by exchange of biochemical substances. Due to internal organization of living systems and variability of external parameters, the exchange is heavily influenced by perturbations of various parameters…

Chaotic Dynamics · Physics 2015-05-19 Dragutin T. Mihailovic , Igor Balaz

Generalized mass-action systems are power-law dynamical systems arising from chemical reaction networks. Essentially, every nonnegative ODE model used in chemistry and biology (for example, in ecology and epidemiology) and even in economics…

Dynamical Systems · Mathematics 2023-11-21 Stefan Müller , Georg Regensburger

In this paper, we introduce a data-driven modeling approach for dynamics problems with latent variables. The state-space of the proposed model includes artificial latent variables, in addition to observed variables that can be fitted to a…

Optimization and Control · Mathematics 2024-06-19 Yushuang Luo , Xiantao Li , Wenrui Hao

Multistationarity in molecular systems underlies switch-like responses in cellular decision making. Determining whether and when a system displays multistationarity is in general a difficult problem. In this work we completely determine the…

Molecular Networks · Quantitative Biology 2020-04-15 E. Feliu , N. Kaihnsa , T. de Wolff , O. Yürük