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The functional network approach, where fMRI BOLD time series are mapped to networks depicting functional relationships between brain areas, has opened new insights into the function of the human brain. In this approach, the choice of…

Neurons and Cognition · Quantitative Biology 2017-11-10 Onerva Korhonen , Heini Saarimäki , Enrico Glerean , Mikko Sams , Jari Saramäki

Deep learning methods are increasingly being used with neuroimaging data like structural and function magnetic resonance imaging (MRI) to predict the diagnosis of neuropsychiatric and neurological disorders. For psychiatric disorders in…

Neurons and Cognition · Quantitative Biology 2019-07-03 Ahmed El Gazzar , Leonardo Cerliani , Guido van Wingen , Rajat Mani Thomas

This article introduces an R package to perform statistical analysis for task-based fMRI data at both individual and group levels. The analysis to detect brain activation at the individual level is based on modeling the fMRI signal using…

Applications · Statistics 2021-11-03 Johnatan Cardona Jiménez

Dynamic functional connectivity is an effective measure for the brain's responses to continuous stimuli. We propose an inferential method to detect the dynamic changes of brain networks based on time-varying graphical models. Whereas most…

Applications · Statistics 2020-06-23 Dingjue Ji , Junwei Lu , Yiliang Zhang , Hongyu Zhao , Siyuan Gao

This study investigated the dynamic connectivity patterns between EEG and fMRI modalities, contributing to our understanding of brain network interactions. By employing a comprehensive approach that integrated static and dynamic analyses of…

Machine Learning · Computer Science 2024-12-02 Guiran Liu , Binrong Zhu

Motivation: In many fMRI studies, respiratory signals are often missing or of poor quality. Therefore, it could be highly beneficial to have a tool to extract respiratory variation (RV) waveforms directly from fMRI data without the need for…

Machine Learning · Computer Science 2024-05-02 Abdoljalil Addeh , Fernando Vega , Rebecca J. Williams , G. Bruce Pike , M. Ethan MacDonald

Accurate fMRI analysis requires sensitivity to temporal structure across multiple scales, as BOLD signals encode cognitive processes that emerge from fast transient dynamics to slower, large-scale fluctuations. Existing deep learning (DL)…

Signal Processing · Electrical Eng. & Systems 2026-01-06 Furkan Genç , Boran İsmet Macun , Sait Sarper Özaslan , Emine U. Saritas , Tolga Çukur

Understanding how the brain's complex nonlinear dynamics give rise to cognitive function remains a central challenge in neuroscience. While brain functional dynamics exhibits scale-free and multifractal properties across temporal scales,…

Neurons and Cognition · Quantitative Biology 2025-06-18 Sangyoon Bae , Junbeom Kwon , Shinjae Yoo , Jiook Cha

Learning-based methods have recently enabled performance leaps in analysis of high-dimensional functional MRI (fMRI) time series. Deep learning models that receive as input functional connectivity (FC) features among brain regions have been…

Signal Processing · Electrical Eng. & Systems 2023-01-03 Irmak Sivgin , Hasan A. Bedel , Şaban Öztürk , Tolga Çukur

The continuous integration of experimental data into coherent models of the brain is an increasing challenge of modern neuroscience. Such models provide a bridge between structure and activity, and identify the mechanisms giving rise to…

Neurons and Cognition · Quantitative Biology 2017-03-03 Jannis Schuecker , Maximilian Schmidt , Sacha J. van Albada , Markus Diesmann , Moritz Helias

Functional magnetic resonance imaging (fMRI) is one of the most common imaging modalities to investigate brain functions. Recent studies in neuroscience stress the great potential of functional brain networks constructed from fMRI data for…

Machine Learning · Computer Science 2022-05-31 Xuan Kan , Hejie Cui , Joshua Lukemire , Ying Guo , Carl Yang

The human brain forms functional networks on all spatial scales. Modern fMRI scanners allow to resolve functional brain data in high resolutions, allowing to study large-scale networks that relate to cognitive processes. The analysis of…

Neurons and Cognition · Quantitative Biology 2019-05-14 Melanie Weber , Johannes Stelzer , Emil Saucan , Alexander Naitsat , Gabriele Lohmann , Jürgen Jost

The human brain exhibits large-scale spontaneous fluctuations that account for most of its total energy metabolism. Independent of any overt function, this immense ongoing activity likely creates or maintains a potential functional brain…

Neurons and Cognition · Quantitative Biology 2021-02-23 Ze Wang

Functional magnetic resonance imaging (fMRI) is used to extract {\em functional networks} connecting correlated human brain sites. Analysis of the resulting networks in different tasks shows that: (a) the distribution of functional…

Disordered Systems and Neural Networks · Physics 2007-05-23 Victor M. Eguiluz , Dante R. Chialvo , Guillermo A. Cecchi , Marwan Baliki , A. Vania Apkarian

Brain network discovery aims to find nodes and edges from the spatio-temporal signals obtained by neuroimaging data, such as fMRI scans of human brains. Existing methods tend to derive representative or average brain networks, assuming…

Machine Learning · Computer Science 2023-11-07 Hang Yin , Yao Su , Xinyue Liu , Thomas Hartvigsen , Yanhua Li , Xiangnan Kong

Understanding the relationship between the structure and function of the human brain is one of the most important open questions in Neurosciences. In particular, Resting State Networks (RSN) and more specifically the Default Mode Network…

Neurons and Cognition · Quantitative Biology 2019-06-14 Julio A. Peraza-Goicolea , Eduardo Martínez-Montes , Eduardo Aubert , Pedro A. Valdés-Hernández , Roberto Mulet

While computer vision models have made incredible strides in static image recognition, they still do not match human performance in tasks that require the understanding of complex, dynamic motion. This is notably true for real-world…

Neurons and Cognition · Quantitative Biology 2025-04-09 Jacob Yeung , Andrew F. Luo , Gabriel Sarch , Margaret M. Henderson , Deva Ramanan , Michael J. Tarr

Early clinical assessment of Alzheimer's disease relies on behavior scores that measure a subject's language, memory, and cognitive skills. On the medical imaging side, functional magnetic resonance imaging has provided invaluable insights…

Signal Processing · Electrical Eng. & Systems 2026-04-14 Javier Salazar Cavazos , Maximillian Egan , Krisanne Litinas , Benjamin Hampstead , Scott Peltier

In recent years,the application of deep learning in task functional Magnetic Resonance Imaging (tfMRI) decoding has led to significant advancements. However,most studies remain constrained by assumption of temporal stationarity in neural…

Machine Learning · Computer Science 2025-03-05 Yueyang Wu , Sinan Yang , Yanming Wang , Jiajie He , Muhammad Mohsin Pathan , Bensheng Qiu , Xiaoxiao Wang

Standard neuroimaging techniques provide non-invasive access not only to human brain anatomy but also to its physiology. The activity recorded with these techniques is generally called functional imaging, but what is observed per se is an…

Neurons and Cognition · Quantitative Biology 2019-02-25 David Papo