Motivation: In many fMRI studies, respiratory signals are often missing or of poor quality. Therefore, it could be highly beneficial to have a tool to extract respiratory variation (RV) waveforms directly from fMRI data without the need for peripheral recording devices. Goal(s): Investigate the hypothesis that head motion parameters contain valuable information regarding respiratory patter, which can help machine learning algorithms estimate the RV waveform. Approach: This study proposes a CNN model for reconstruction of RV waveforms using head motion parameters and BOLD signals. Results: This study showed that combining head motion parameters with BOLD signals enhances RV waveform estimation. Impact: It is expected that application of the proposed method will lower the cost of fMRI studies, reduce complexity, and decrease the burden on participants as they will not be required to wear a respiratory bellows.
@article{arxiv.2405.00219,
title = {Machine Learning-based Estimation of Respiratory Fluctuations in a Healthy Adult Population using BOLD fMRI and Head Motion Parameters},
author = {Abdoljalil Addeh and Fernando Vega and Rebecca J. Williams and G. Bruce Pike and M. Ethan MacDonald},
journal= {arXiv preprint arXiv:2405.00219},
year = {2024}
}