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Suppose Alice holds a DNA sequence and Bob owns a database of DNA sequences. They want to determine whether there is a match for the Alice's input in the Bob's database for any purpose such as diagnosis of Alice's disease. However, Alice…

Cryptography and Security · Computer Science 2018-09-25 Parisa Kaghazgaran

When an individual's DNA is sequenced, sensitive medical information becomes available to the sequencing laboratory. A recently proposed way to hide an individual's genetic information is to mix in DNA samples of other individuals. We…

Information Theory · Computer Science 2024-11-05 Kayvon Mazooji , Roy Dong , Ilan Shomorony

Current techniques in sequencing a genome allow a service provider (e.g. a sequencing company) to have full access to the genome information, and thus the privacy of individuals regarding their lifetime secret is violated. In this paper, we…

Genomics · Quantitative Biology 2018-11-28 Ali Gholami , Mohammad Ali Maddah-Ali , Seyed Abolfazl Motahari

We live in a period where bio-informatics is rapidly expanding, a significant quantity of genomic data has been produced as a result of the advancement of high-throughput genome sequencing technology, raising concerns about the costs…

Quantitative Methods · Quantitative Biology 2023-03-10 Mehedi Hasan Sarkar , Adnan Ferdous Ashrafi

We study the degree to which a character string, $Q$, leaks details about itself any time it engages in comparison protocols with a strings provided by a querier, Bob, even if those protocols are cryptographically guaranteed to produce no…

Data Structures and Algorithms · Computer Science 2016-11-15 Michael T. Goodrich

DNA sequencing has faced a huge demand since it was first introduced as a service to the public. This service is often offloaded to the sequencing companies who will have access to full knowledge of individuals' sequences, a major violation…

Information Theory · Computer Science 2019-04-04 Ali Gholami , Mohammad Ali Maddah-Ali , Seyed Abolfazl Motahari

Motivation: Researchers need a rich trove of genomic datasets that they can leverage to gain a better understanding of the genetic basis of the human genome and identify associations between phenotypes and specific parts of DNA. However,…

Cryptography and Security · Computer Science 2021-06-10 Nour Almadhoun Alserr , Gulce Kale , Onur Mutlu , Oznur Tastan , Erman Ayday

DNA fingerprinting is a cornerstone for human identification in forensics, where the sequence of highly polymorphic short tandem repeats (STRs) from an individual is compared against a DNA database. This presents significant privacy risks…

Cryptography and Security · Computer Science 2021-03-30 Taeho Jung , Ryan Karl , Geoffrey H. Siwo

The task of calculating similarities between strings held by different organizations without revealing these strings is an increasingly important problem in areas such as health informatics, national censuses, genomics, and fraud detection.…

Databases · Computer Science 2021-04-08 Sirintra Vaiwsri , Thilina Ranbaduge , Peter Christen , Kee Siong Ng

Consider two parties who want to compare their strings, e.g., genomes, but do not want to reveal them to each other. We present a system for privacy-preserving matching of strings, which differs from existing systems by providing a…

Cryptography and Security · Computer Science 2013-02-13 Martin Beck , Florian Kerschbaum

We show new lower bounds on the sample complexity of $(\varepsilon, \delta)$-differentially private algorithms that accurately answer large sets of counting queries. A counting query on a database $D \in (\{0,1\}^d)^n$ has the form "What…

Cryptography and Security · Computer Science 2018-10-25 Mark Bun , Jonathan Ullman , Salil Vadhan

Private queries allow a user Alice to learn an element of a database held by a provider Bob without revealing which element she was interested in, while limiting her information about the other elements. We propose to implement private…

Privacy is of the utmost importance in genomic matching. Therefore a number of privacy-preserving protocols have been presented using secure computation. Nevertheless, none of these protocols prevents inferences from the result. Goodrich…

Cryptography and Security · Computer Science 2014-05-02 Florian Kerschbaum , Martin Beck , Dagmar Schönfeld

In two-party quantum communication complexity, Alice and Bob receive some classical inputs and wish to compute some function that depends on both these inputs, while minimizing the communication. This model has found numerous applications…

Quantum Physics · Physics 2021-10-05 Iordanis Kerenidis , Mathieu Laurière , François Le Gall , Mathys Rennela

We analyze the security of a quantum secure direct communication protocol equipped with authentication. We first propose a specifc attack on the protocol by which, an adversary can break the secret already shared between Alice and Bob, when…

Quantum Physics · Physics 2016-09-30 Ali Amerimehr , Massoud Hadian Dehkordi

Quantum private query (QPQ) is a kind of quantum protocols to protect both users' privacy in their communication. There is an interesting example, that is, Alice wants to buy one item from Bob's database, which is composed of a quantity of…

Quantum Physics · Physics 2014-10-09 Fei Gao , Bin Liu , Wei Huang , Qiao-Yan Wen

Differential privacy (DP) considers a scenario, where an adversary has almost complete information about the entries of a database This worst-case assumption is likely to overestimate the privacy thread for an individual in real life.…

Cryptography and Security · Computer Science 2025-04-16 Dennis Breutigam , Rüdiger Reischuk

DNA fingerprinting and matching for identifying suspects has been a common practice in criminal investigation. Such proceedings involve multiple parties such as investigating agencies, suspects and forensic labs. A major challenge in such…

Cryptography and Security · Computer Science 2024-09-24 Sankha Das

We develop a novel approximate Bayesian computation (ABC) framework, ABCDP, that produces differentially private (DP) and approximate posterior samples. Our framework takes advantage of the Sparse Vector Technique (SVT), widely studied in…

Machine Learning · Statistics 2021-02-10 Mijung Park , Margarita Vinaroz , Wittawat Jitkrittum

In recent years, an increasing amount of data is collected in different and often, not cooperative, databases. The problem of privacy-preserving, distributed calculations over separated databases and, a relative to it, issue of private data…

Databases · Computer Science 2016-05-23 Philip Derbeko , Shlomi Dolev , Ehud Gudes , Jeffrey D. Ullman
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