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Synapses change on multiple timescales, ranging from milliseconds to minutes, due to a combination of both short- and long-term plasticity. Here we develop an extension of the common Generalized Linear Model to infer both short- and…

Neurons and Cognition · Quantitative Biology 2022-08-15 Ganchao Wei , Ian H. Stevenson

To mitigate forgetting, existing lifelong event detection methods typically maintain a memory module and replay the stored memory data during the learning of a new task. However, the simple combination of memory data and new-task samples…

Computation and Language · Computer Science 2024-04-04 Chengwei Qin , Ruirui Chen , Ruochen Zhao , Wenhan Xia , Shafiq Joty

With the explosive growth of data, long-sequence modeling has become increasingly important in tasks such as natural language processing and bioinformatics. However, existing methods face inherent trade-offs between efficiency and memory.…

Machine Learning · Computer Science 2025-10-07 Youjin Wang , Yangjingyi Chen , Jiahao Yan , Jiaxuan Lu , Xiao Sun

Memory is a complex phenomenon that involves several distinct mechanisms. These mechanisms operate at different spatial and temporal levels. This chapter focuses on the theoretical framework and the mathematical models that have been…

Neurons and Cognition · Quantitative Biology 2021-12-22 Stefano Fusi

Lifelong learning requires models that can continuously learn from sequential streams of data without suffering catastrophic forgetting due to shifts in data distributions. Deep learning models have thrived in the non-sequential learning…

Computation and Language · Computer Science 2021-07-27 Nithin Holla , Pushkar Mishra , Helen Yannakoudakis , Ekaterina Shutova

It has been observed that neural networks perform poorly when the data or tasks are presented sequentially. Unlike humans, neural networks suffer greatly from catastrophic forgetting, making it impossible to perform life-long learning. To…

Machine Learning · Computer Science 2023-01-31 Longhui Yu , Tianyang Hu , Lanqing Hong , Zhen Liu , Adrian Weller , Weiyang Liu

In-Context Learning (ICL) in transformers acts as an online associative memory and is believed to underpin their high performance on complex sequence processing tasks. However, in gated linear attention models, this memory has a fixed…

Machine Learning · Computer Science 2026-02-12 Djohan Bonnet , Jamie Lohoff , Jan Finkbeiner , Elidona Skhikerujah , Emre Neftci

This paper addresses the limitations of large language models in understanding long-term context. It proposes a model architecture equipped with a long-term memory mechanism to improve the retention and retrieval of semantic information…

Computation and Language · Computer Science 2025-05-30 Yue Xing , Tao Yang , Yijiashun Qi , Minggu Wei , Yu Cheng , Honghui Xin

Large Language Models (LLMs) are often evaluated against ideals of perfect Bayesian inference, yet growing evidence suggests that their in-context reasoning exhibits systematic forgetting of past information. Rather than viewing this…

Computation and Language · Computer Science 2026-04-08 Alexandros Christoforos

We present an account of neuroplasticity with respect to cell-internal processing pathways in relation to membrane and synaptic plasticity. We think traditional synapse-centric, weight-based models of memorization are not sufficient or…

Neurons and Cognition · Quantitative Biology 2026-04-27 Gabriele Scheler

What is the physiological basis of long-term memory? The prevailing view in neuroscience attributes changes in synaptic efficacy to memory acquisition. This view implies that stable memories correspond to stable connectivity patterns.…

Neurons and Cognition · Quantitative Biology 2019-10-09 Lee Susman , Naama Brenner , Omri Barak

A central challenge in developing versatile machine learning systems is catastrophic forgetting: a model trained on tasks in sequence will suffer significant performance drops on earlier tasks. Despite the ubiquity of catastrophic…

Machine Learning · Computer Science 2020-07-16 Vinay V. Ramasesh , Ethan Dyer , Maithra Raghu

Several guiding principles for thought processes are proposed and a neural-network-type model implementing these principles is presented and studied. We suggest to consider thinking within an associative network built-up of overlapping…

Neurons and Cognition · Quantitative Biology 2007-05-23 Claudius Gros

Intersectoral dynamic models with power-law memory are proposed. The equations of open and closed intersectoral models, in which the memory effects are described by the Caputo derivatives of non-integer orders, are derived. We suggest…

Economics · Quantitative Finance 2017-12-27 Valentina V. Tarasova , Vasily E. Tarasov

Contextual memory integration remains a high challenge in the development of language models, particularly in tasks that require maintaining coherence over extended sequences. Traditional approaches, such as self-attention mechanisms and…

Computation and Language · Computer Science 2025-08-11 George Applegarth , Christian Weatherstone , Maximilian Hollingsworth , Henry Middlebrook , Marcus Irvin

Neural networks can achieve excellent results in a wide variety of applications. However, when they attempt to sequentially learn, they tend to learn the new task while catastrophically forgetting previous ones. We propose a model that…

Machine Learning · Computer Science 2020-12-18 Craig Atkinson , Brendan McCane , Lech Szymanski , Anthony Robins

In Hopfield-type associative memory models, memories are stored in the connectivity matrix and can be retrieved subsequently thanks to the collective dynamics of the network. In these models, the retrieval of a particular memory can be…

Neurons and Cognition · Quantitative Biology 2025-10-21 Marco Benedetti , Nicolas Brunel , Enzo Marinari , Ulises Pereira Obilinovic

Biological synapses store multiple memories on top of each other in a palimpsest fashion and at different timescales. Palimpsest consolidation is facilitated by the interaction of hidden biochemical processes that govern synaptic efficacy…

Neurons and Cognition · Quantitative Biology 2021-09-28 Christos Giotis , Alexander Serb , Vasileios Manouras , Spyros Stathopoulos , Themis Prodromakis

Sequence memory is an essential attribute of natural and artificial intelligence that enables agents to encode, store, and retrieve complex sequences of stimuli and actions. Computational models of sequence memory have been proposed where…

Neural and Evolutionary Computing · Computer Science 2023-11-06 Hamza Tahir Chaudhry , Jacob A. Zavatone-Veth , Dmitry Krotov , Cengiz Pehlevan

Synaptic memory is considered to be the main element responsible for learning and cognition in humans. Although traditionally non-volatile long-term plasticity changes have been implemented in nanoelectronic synapses for neuromorphic…

Emerging Technologies · Computer Science 2017-12-20 Abhronil Sengupta , Kaushik Roy