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Memory and forgetting constitute two sides of the same coin, and although the first has been rigorously investigated, the latter is often overlooked. A number of experiments under the realm of psychology and experimental neuroscience have…

Neurons and Cognition · Quantitative Biology 2019-07-23 Antonios Georgiou , Mikhail Katkov , Misha Tsodyks

We first review traditional approaches to memory storage and formation, drawing on the literature of quantitative neuroscience as well as statistical physics. These have generally focused on the fast dynamics of neurons; however, there is…

Neurons and Cognition · Quantitative Biology 2018-07-24 Anita Mehta

Short-term memory in the brain cannot in general be explained the way long-term memory can -- as a gradual modification of synaptic weights -- since it takes place too quickly. Theories based on some form of cellular bistability, however,…

Neurons and Cognition · Quantitative Biology 2013-01-31 Samuel Johnson , J. Marro , Joaquín J. Torres

Late long-term potentiation (L-LTP) appears essential for the formation of long-term memory, with memories at least partly encoded by patterns of strengthened synapses. How memories are preserved for months or years, despite molecular…

Neurons and Cognition · Quantitative Biology 2015-05-13 Paul Smolen

We focus on emergence of the power-law cross-correlations from processes with both short and long term memory properties. In the case of correlated error-terms, the power-law decay of the cross-correlation function comes automatically with…

Methodology · Statistics 2014-12-11 Ladislav Kristoufek

Competitive dynamics are thought to occur in many processes of learning involving synaptic plasticity. Here we show, in a game theory-inspired model of synaptic interactions, that the competition between synapses in their weak and strong…

Disordered Systems and Neural Networks · Physics 2015-05-28 Gaurang Mahajan , Anita Mehta

Memories are stored, retained, and recollected through complex, coupled processes operating on multiple timescales. To understand the computational principles behind these intricate networks of interactions we construct a broad class of…

Neurons and Cognition · Quantitative Biology 2015-07-29 Marcus K. Benna , Stefano Fusi

Unlike humans, who are capable of continual learning over their lifetimes, artificial neural networks have long been known to suffer from a phenomenon known as catastrophic forgetting, whereby new learning can lead to abrupt erasure of…

Artificial Intelligence · Computer Science 2018-06-20 Christos Kaplanis , Murray Shanahan , Claudia Clopath

Recent studies have shown that metaplastic synapses can retain information longer than simple binary synapses and are beneficial for continual learning. In this paper, we explore the multistate metaplastic synapse characteristics in the…

Neural and Evolutionary Computing · Computer Science 2020-03-27 Fatima Tuz Zohora , Abdullah M. Zyarah , Nicholas Soures , Dhireesha Kudithipudi

Sequential information contains short- to long-range dependencies; however, learning long-timescale information has been a challenge for recurrent neural networks. Despite improvements in long short-term memory networks (LSTMs), the…

Machine Learning · Computer Science 2021-05-14 Hsiang-Yun Sherry Chien , Javier S. Turek , Nicole Beckage , Vy A. Vo , Christopher J. Honey , Ted L. Willke

Loss of plasticity is one of the main challenges in continual learning with deep neural networks, where neural networks trained via backpropagation gradually lose their ability to adapt to new tasks and perform significantly worse than…

Machine Learning · Computer Science 2025-03-27 Jiuqi Wang , Rohan Chandra , Shangtong Zhang

Memory is often defined as the mental capacity of retaining information about facts, events, procedures and more generally about any type of previous experience. Memories are remembered as long as they influence our thoughts, feelings, and…

Neurons and Cognition · Quantitative Biology 2017-06-16 Stefano Fusi

Unlike the brain, artificial neural networks, including state-of-the-art deep neural networks for computer vision, are subject to "catastrophic forgetting": they rapidly forget the previous task when trained on a new one. Neuroscience…

Neural and Evolutionary Computing · Computer Science 2021-06-09 Axel Laborieux , Maxence Ernoult , Tifenn Hirtzlin , Damien Querlioz

Memories are stored, at least partly, as patterns of strong synapses. Given molecular turnover, how can synapses maintain strong for the years that memories can persist? Some models postulate that biochemical bistability maintains strong…

Neurons and Cognition · Quantitative Biology 2015-04-09 Paul Smolen

Conventional intelligent systems based on deep neural network (DNN) models encounter challenges in achieving human-like continual learning due to catastrophic forgetting. Here, we propose a metaplasticity model inspired by human working…

Neural and Evolutionary Computing · Computer Science 2024-07-11 Suhee Cho , Hyeonsu Lee , Seungdae Baek , Se-Bum Paik

We analyze continuous Hopfield associative memories augmented by additional, rapid short-term associative synaptic plasticity. Through the cavity method, we determine the boundary between the retrieval and forgetting, or spin-glass phase,…

Neurons and Cognition · Quantitative Biology 2026-02-10 Martina Del Gaudio , Federico Ghimenti , Surya Ganguli

In terms of energy efficiency and computational speed, neuromorphic electronics based on non-volatile memory devices is expected to be one of most promising hardware candidates for future artificial intelligence (AI). However, catastrophic…

Neural and Evolutionary Computing · Computer Science 2024-01-29 Lifu Zhang , Ji-An Li , Yang Hu , Jie Jiang , Rongjie Lai , Marcus K. Benna , Jian Shi

While deep neural networks have surpassed human performance in multiple situations, they are prone to catastrophic forgetting: upon training a new task, they rapidly forget previously learned ones. Neuroscience studies, based on idealized…

Neural and Evolutionary Computing · Computer Science 2021-03-24 Axel Laborieux , Maxence Ernoult , Tifenn Hirtzlin , Damien Querlioz

It is known that storage capacity per synapse increases by synaptic pruning in the case of a correlation-type associative memory model. However, the storage capacity of the entire network then decreases. To overcome this difficulty, we…

Disordered Systems and Neural Networks · Physics 2007-05-23 Seiji Miyoshi , Masato Okada

Why do we forget? Why do we remember things that never happened? The conventional answer points to biological hardware. We propose a different one: geometry. Here we show that high-dimensional embedding spaces, subjected to noise,…

Neurons and Cognition · Quantitative Biology 2026-04-09 Sambartha Ray Barman , Andrey Starenky , Sophia Bodnar , Nikhil Narasimhan , Ashwin Gopinath
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