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The potential outcomes framework serves as a fundamental tool for quantifying causal effects. The average dose-response function (also called the effect curve), denoted as (\mu(t)), is typically of interest when dealing with a continuous…

Methodology · Statistics 2025-07-21 Juraj Bodik

Since its debut in the 18th century, the P-value has been an important part of hypothesis testing-based scientific discoveries. As the statistical engine accelerates, questions are beginning to be raised, asking to what extent scientific…

$\textbf{Motivation:}$ Small $p$-values are often required to be accurately estimated in large-scale genomic studies for the adjustment of multiple hypothesis tests and the ranking of genomic features based on their statistical…

Applications · Statistics 2023-08-29 Yang Shi , Mengqiao Wang , Weiping Shi , Ji-Hyun Lee , Huining Kang , Hui Jiang

Classical and more recent tests for detecting distributional changes in multivariate time series often lack power against alternatives that involve changes in the cross-sectional dependence structure. To be able to detect such changes…

Statistics Theory · Mathematics 2014-09-16 Axel Bücher , Ivan Kojadinovic , Tom Rohmer , Johan Segers

Identifying anomalies and contamination in datasets is important in a wide variety of settings. In this paper, we describe a new technique for estimating contamination in large, discrete valued datasets. Our approach considers the normal…

Information Theory · Computer Science 2015-06-16 Matthew L. Malloy , Scott Alfeld , Paul Barford

Identifying a biomarker or treatment-dose threshold that marks a specified level of risk is an important problem, especially in clinical trials. This risk, viewed as a function of thresholds and possibly adjusted for covariates, we call the…

Methodology · Statistics 2023-03-22 Lars van der Laan , Wenbo Zhang , Peter B. Gilbert

We study the distribution of hard-, soft-, and adaptive soft-thresholding estimators within a linear regression model where the number of parameters k can depend on sample size n and may diverge with n. In addition to the case of known…

Statistics Theory · Mathematics 2012-01-04 Benedikt M. Pötscher , Ulrike Schneider

We propose an approach to better inform treatment decisions at an individual level by adapting recent advances in average treatment effect estimation to conditional average treatment effect estimation. Our work is based on doubly robust…

Methodology · Statistics 2023-06-13 Aaron Fisher , Virginia Fisher

It can be difficult to interpret a coefficient of an uncertain model. A slope coefficient of a regression model may change as covariates are added or removed from the model. In the context of high-dimensional data, there are too many model…

Methodology · Statistics 2024-08-20 Brian Knaeble , R. Mitchell Hughes , George Rudolph , Mark A. Abramson , Daniel Razo

We consider parametric estimation of the continuous part of a class of ergodic diffusions with jumps based on high-frequency samples. Various papers previously proposed threshold based methods, which enable us to distinguish whether…

Methodology · Statistics 2019-10-02 Hiroki Masuda , Yuma Uehara

Rerandomization enforces covariate balance across treatment groups in the design stage of experiments. Despite its intuitive appeal, its theoretical justification remains unsatisfying because its benefits of improving efficiency for…

Statistics Theory · Mathematics 2025-05-05 Xin Lu , Peng Ding

A function of the empirical characteristic function,exists for the stable distribution, which leads to a linear regression and can be used to estimate the parameters. Two approaches are often used, one to find optimal values of t, but these…

Computation · Statistics 2018-11-06 J. Martin van Zyl

We propose a framework combining detrended fluctuation analysis with standard regression methodology. The method is built on detrended variances and covariances and it is designed to estimate regression parameters at different scales and…

Statistical Finance · Quantitative Finance 2018-10-30 Ladislav Kristoufek

In applied multivariate statistics, estimating the number of latent dimensions or the number of clusters, $k$, is a fundamental and recurring problem. We study a sequence of statistics called "cross-validated eigenvalues." Under a large…

Methodology · Statistics 2025-12-24 Fan Chen , Sebastien Roch , Karl Rohe , Shuqi Yu

The higher criticism of a family of tests starts with the individual uncorrected p-values of each test. It then requires a procedure for deciding whether the collection of p-values indicates the presence of a real effect and if possible…

Regular variation is often used as the starting point for modeling multivariate heavy-tailed data. A random vector is regularly varying if and only if its radial part $R$ is regularly varying and is asymptotically independent of the angular…

Statistics Theory · Mathematics 2018-03-28 Phyllis Wan , Richard A. Davis

Identifying the instances of jumps in a discrete-time-series sample of a jump diffusion model is a challenging task. We have developed a novel statistical technique for jump detection and volatility estimation in a return time series data…

Statistical Finance · Quantitative Finance 2022-03-22 Milan Kumar Das , Anindya Goswami , Sharan Rajani

Estimation of a regression function from independent and identically distributed random variables is considered. The $L_2$ error with integration with respect to the design measure is used as an error criterion. Over-parametrized deep…

Statistics Theory · Mathematics 2022-10-05 Michael Kohler , Adam Krzyzak

Linear thresholding models postulate that the conditional distribution of a response variable in terms of covariates differs on the two sides of a (typically unknown) hyperplane in the covariate space. A key goal in such models is to learn…

Statistics Theory · Mathematics 2021-10-01 Debarghya Mukherjee , Moulinath Banerjee , Debasri Mukherjee , Ya'acov Ritov

Modern statistics provides an ever-expanding toolkit for estimating unknown parameters. Consequently, applied statisticians frequently face a difficult decision: retain a parameter estimate from a familiar method or replace it with an…

Methodology · Statistics 2022-12-20 Brian L. Trippe , Sameer K. Deshpande , Tamara Broderick