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Sequence alignment is a fundamental process in computational biology which identifies regions of similarity in biological sequences. With the exponential growth in the volume of data in bioinformatics databases, the time, processing power,…

Hardware Architecture · Computer Science 2025-07-31 Nasrin Akbari , Mehdi Modarressi , Alireza Khadem

Many high end and next generation computing systems to incorporated alternative memory technologies to meet performance goals. Since these technologies present distinct advantages and tradeoffs compared to conventional DDR* SDRAM, such as…

Performance · Computer Science 2021-10-06 M. Ben Olson , Brandon Kammerdiener , Kshitij A. Doshi , Terry Jones , Michael R. Jantz

Algorithm research focuses primarily on how many operations processors need to do (time complexity). But for many problems, both the runtime and energy used are dominated by memory accesses. In this paper, we present the first broad survey…

Data Structures and Algorithms · Computer Science 2025-12-01 Hayden Rome , Jayson Lynch , Jeffery Li , Chirag Falor , Neil Thompson

Leadership supercomputers feature a diversity of storage, from node-local persistent memory and NVMe SSDs to network-interconnected flash memory and HDD. Memory mapping files on different tiers of storage provides a uniform interface in…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-10-18 Ivy B. Peng , Marty McFadden , Eric Green , Keita Iwabuchi , Kai Wu , Dong Li , Roger Pearce , Maya Gokhale

Memory system is often the main bottleneck in chipmultiprocessor (CMP) systems in terms of latency, bandwidth and efficiency, and recently additionally facing capacity and power problems in an era of big data. A lot of research works have…

Hardware Architecture · Computer Science 2014-04-10 Licheng Chen , Tianyue Lu , Yanan Wang , Mingyu Chen , Yuan Ruan , Zehan Cui , Yongbing Huang , Mingyang Chen , Jiutian Zhang , Yungang Bao

Industries are recently considering the adoption of cloud computing for hosting safety critical applications. However, the use of multicore processors usually adopted in the cloud introduces temporal anomalies due to contention for shared…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-06-30 Giorgio Farina , Gautam Gala , Marcello Cinque , Gerhard Fohler

HPC applications pose high demands on I/O performance and storage capability. The emerging non-volatile memory (NVM) techniques offer low-latency, high bandwidth, and persistence for HPC applications. However, the existing I/O stack are…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-05-11 Wei Liu , Kai Wu , Jialin Liu , Feng Chen , Dong Li

Offloading compute-intensive kernels to hardware accelerators relies on the large degree of parallelism offered by these platforms. However, the effective bandwidth of the memory interface often causes a bottleneck, hindering the…

Hardware Architecture · Computer Science 2022-02-25 Corentin Ferry , Tomofumi Yuki , Steven Derrien , Sanjay Rajopadhye

Multi-tiered large memory systems call for rethinking of memory profiling and migration because of the unique problems unseen in the traditional memory systems with smaller capacity and fewer tiers. We develop MTM, an…

Performance · Computer Science 2023-05-03 Jie Ren , Dong Xu , Ivy Peng , Junhee Ryu , Kwangsik Shin , Daewoo Kim , Dong Li

Bandwidth-starved multicore chips have become ubiquitous. It is well known that the performance of stencil codes can be improved by temporal blocking, lessening the pressure on the memory interface. We introduce a new pipelined approach…

Distributed, Parallel, and Cluster Computing · Computer Science 2010-06-17 Markus Wittmann , Georg Hager , Jan Treibig , Gerhard Wellein

The main memory access latency has not much improved for more than two decades while the CPU performance had been exponentially increasing until recently. Approximate memory is a technique to reduce the DRAM access latency in return of…

Emerging Technologies · Computer Science 2021-01-27 Soramichi Akiyama , Ryota Shioya

Disk access latency and transfer times are often considered to have a major and detrimental impact on the running time of software. Developers are often advised to favour in-memory operations and minimise disk access. Furthermore, diskless…

Other Computer Science · Computer Science 2015-03-31 Kamran Karimi , Diwakar Krishnamurthy , Parissa Mirjafari

We demonstrate that general-purpose memory allocation involving many threads on many cores can be done with high performance, multicore scalability, and low memory consumption. For this purpose, we have designed and implemented scalloc, a…

Programming Languages · Computer Science 2015-08-26 Martin Aigner , Christoph M. Kirsch , Michael Lippautz , Ana Sokolova

Concurrent data structures often require additional memory for handling synchronization issues in addition to memory for storing elements. Depending on the amount of this additional memory, implementations can be more or less…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-01-17 Vitaly Aksenov , Nikita Koval , Petr Kuznetsov , Anton Paramonov

To process data that do not fit in RAM, conventional wisdom would suggest using distributed approaches. However, recent research has demonstrated virtual memory's strong potential in scaling up graph mining algorithms on a single machine.…

Machine Learning · Computer Science 2016-04-12 Dezhi Fang , Duen Horng Chau

Operating systems include many heuristic algorithms designed to improve overall storage performance and throughput. Because such heuristics cannot work well for all conditions and workloads, system designers resorted to exposing numerous…

Heterogeneous Memory Architecture (HMA) aims to optimize memory usage by leveraging a combination of memory types, such as high-bandwidth memory (HBM), commodity DRAM, and non-volatile memory (NVM), when utilized as main memory. To achieve…

Hardware Architecture · Computer Science 2026-04-23 Upasna , Venkata Kalyan Tavva

The availability of unprecedented unsupervised training data, along with neural scaling laws, has resulted in an unprecedented surge in model size and compute requirements for serving/training LLMs. However, the main performance bottleneck…

Machine Learning · Computer Science 2024-03-22 Amir Gholami , Zhewei Yao , Sehoon Kim , Coleman Hooper , Michael W. Mahoney , Kurt Keutzer

Virtualization, after having found widespread adoption in the server and desktop arena, is poised to change the architecture of embedded systems as well. The benefits afforded by virtualization - enhanced isolation, manageability,…

Operating Systems · Computer Science 2018-06-05 Janis Danisevskis , Michael Peter , Jan Nordholz

We study a generalization of the classic paging problem that allows the amount of available memory to vary over time - capturing a fundamental property of many modern computing realities, from cloud computing to multi-core and…

Data Structures and Algorithms · Computer Science 2013-04-23 Enoch Peserico