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Computer hardware costs are the limiting factor in producing highly accurate radiation dose calculations on convenient time scales. Because of this, large-scale, full Monte Carlo simulations and other resource intensive algorithms are often…

Medical Physics · Physics 2010-09-28 Roy W. Keyes , Christian Romano , Dorian Arnold , Shuang Luan

Purpose: This work advances a Monte Carlo (MC) method to combine ionizing radiation physics with optical physics, in a manner which was implicitly designed for deployment with the most widely accessible parallelization and portability…

Medical Physics · Physics 2020-05-05 Ethan P. M. LaRochelle , Pedro Arce , Brian W. Pogue

Monte Carlo (MC) simulation is considered the gold standard method for radiotherapy dose calculation. However, achieving high precision requires a large number of simulation histories, which is time consuming. The use of computer graphics…

Computer Vision and Pattern Recognition · Computer Science 2020-12-24 Ti Bai , Biling Wang , Dan Nguyen , Steve Jiang

An essential component in proton radiotherapy is the algorithm to calculate the radiation dose to be delivered to the patient. The most common dose algorithms are fast but they are approximate analytical approaches. However their level of…

Medical Physics · Physics 2015-05-20 Pablo P Yepes , Dragan Mirkovic , Phillip J Taddei

Monte Carlo (MC) simulation is commonly considered to be the most accurate dose calculation method in radiotherapy. However, its efficiency still requires improvement for many routine clinical applications. In this paper, we present our…

Medical Physics · Physics 2015-05-28 Xun Jia , Xuejun Gu , Yan Jiang Graves , Michael Folkerts , Steve B. Jiang

The use of GEANT4 code has increased in the medical field. There are various studies to calculate the patient dose distributions with the GEANT4 code using the imaging data. In present study, the Monte Carlo simulations based on the DICOM…

Medical Physics · Physics 2015-03-18 JeongOk Lee , JeongKu Kang , JhinKee Kim , HyeongCheol Kwon , JungSoo Kim , BuGil Kim , DongHyeok Jeong

Monte Carlo simulation is the most accurate method for absorbed dose calculations in radiotherapy. Its efficiency still requires improvement for routine clinical applications, especially for online adaptive radiotherapy. In this paper, we…

Medical Physics · Physics 2015-05-14 Xun Jia , Xuejun Gu , Josep Sempau , Dongju Choi , Amitava Majumdar , Steve B. Jiang

Monte Carlo (MC) method has been recognized the most accurate dose calculation method for radiotherapy. However, its extremely long computation time impedes clinical applications. Recently, a lot of efforts have been made to realize fast MC…

Medical Physics · Physics 2017-02-08 Zhen Tian , Feng Shi , Michael Folkerts , Nan Qin , Steve B. Jiang , Xun Jia

Purpose: The presence of respiratory motion during radiation treatment leads to degradation of the expected dose distribution, both for target coverage and healthy-tissue sparing, particularly for techniques like pencil-beam scanning proton…

A novel phase-space source implementation has been designed for GPU-based Monte Carlo dose calculation engines. Due to the parallelized nature of GPU hardware, it is essential to simultaneously transport particles of the same type and…

Medical Physics · Physics 2013-06-21 Reid Townson , Xun Jia , Zhen Tian , Yan Jiang Graves , Sergei Zavgorodni , Steve B Jiang

We assess costs and efficiency of state-of-the-art high performance cloud computing compared to a traditional on-premises compute cluster. Our use case are atomistic simulations carried out with the GROMACS molecular dynamics (MD) toolkit…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-05-16 Carsten Kutzner , Christian Kniep , Austin Cherian , Ludvig Nordstrom , Helmut Grubmüller , Bert L. de Groot , Vytautas Gapsys

Accurate proton dose calculation using Monte Carlo (MC) is computationally demanding in workflows like robust optimisation, adaptive replanning, and probabilistic inference, which require repeated evaluations. To address this, we develop a…

Machine Learning · Statistics 2025-09-24 Aaron Pim , Tristan Pryer

We discuss the efficiency of Monte Carlo methods in solving continuum radiative transfer problems. The sampling of the radiation field and convergence of dust temperature calculations in the case of optically thick clouds are both studied.…

Astrophysics · Physics 2009-11-10 M. Juvela

Novel radiotherapy techniques like synchrotron X-ray microbeam radiation therapy (MRT), require fast dose distribution predictions that are accurate at the sub-mm level, especially close to tissue/bone/air interfaces. Monte Carlo physics…

Cloud computing offers a variable-cost payment scheme that allows cloud customers to specify the price they are willing to pay for renting spot instances to run their applications at much lower costs than fixed payment schemes, and…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-10-13 Abdullah Alourani , Ajay D. Kshemkalyani

Recently, X-ray imaging dose from computed tomography (CT) or cone beam CT (CBCT) scans has become a serious concern. Patient-specific imaging dose calculation has been proposed for the purpose of dose management. While Monte Carlo (MC)…

Medical Physics · Physics 2015-05-30 Xun Jia , Hao Yan , Xuejun Gu , Steve B. Jiang

Purpose: To develop a Monte Carlo (MC) therapeutic dose calculation toolkit of a recently released ring gantry linac in Geant4 (Version 10.7) for secondary dose validation of radiotherapy plan. Methods: For the Halcyon (Varian Medical…

Medical Physics · Physics 2022-10-04 Ruirui Liu , Zhen Ji , Xiandong Zhao , Tianyu Zhao , Abhishek Sethi , Daren Sawkey , Bin Cai

The Fast Dose Calculator (FDC), a track repeating algorithm Monte Carlo method was initially developed for proton therapy. The validation for proton therapy has been demonstrated in a previous work. This method can be expanded to ion…

Medical Physics · Physics 2018-09-18 Qianxia Wang , Antony Adair , Yu Deng , Hongliang Chen , M Moyers , James Lin , Pablo Yepes

Deploying big-data Machine Learning (ML) services in a cloud environment presents a challenge to the cloud vendor with respect to the cloud container configuration sizing for any given customer use case. OracleLabs has developed an…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-03-19 Guang Chao Wang , Kenny Gross , Akshay Subramaniam

Monte Carlo simulation is an essential tool in emission tomography that can assist in the design of new medical imaging devices, the optimization of acquisition protocols, and the development or assessment of image reconstruction algorithms…

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