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Using a stochastic nonlinear phase oscillator model, we study the effect of event-triggered feedback on the statistics of interevent intervals. Events are associated with the entering of a new cycle. The feedback is modeled by an…

Data Analysis, Statistics and Probability · Physics 2015-06-18 Justus A. Kromer , Benjamin Lindner , Lutz Schimansky-Geier

The dynamics of an ensemble of bistable elements with global time-delayed coupling under the influence of noise is studied analytically and numerically. Depending on the noise level the system undergoes ordering transitions and demonstrates…

Statistical Mechanics · Physics 2009-11-10 D. Huber , L. S. Tsimring

Single-cell studies often show significant phenotypic variability due to the stochastic nature of intra-cellular biochemical reactions. When the numbers of molecules, e.g., transcription factors and regulatory enzymes, are in low abundance,…

Quantitative Methods · Quantitative Biology 2015-06-17 Kyung Hyuk Kim , Hong Qian , Herbert M. Sauro

Motivated by the aim to find new medical strategies to suppress undesirable neural synchronization we study the control of oscillations in a system of inhibitory coupled noisy oscillators. Using dynamical properties of inhibition, we find…

Disordered Systems and Neural Networks · Physics 2009-05-27 C. J. Tessone , E. Ullner , A. A. Zaikin , J. Kurths , R. Toral

Multirhythmicity, a form of multistability, in an oscillator is an intriguing phenomenon found across many branches of science. From an application point of view, while the multirhythmicity is sometimes desirable as it presents us with many…

Adaptation and Self-Organizing Systems · Physics 2021-02-03 Sandip Saha , Sagar Chakraborty , Gautam Gangopadhyay

Genetic oscillators, such as circadian clocks, are constantly perturbed by molecular noise arising from the small number of molecules involved in gene regulation. One of the strongest sources of stochasticity is the binary noise that arises…

Biological Physics · Physics 2016-01-06 Sargis Karapetyan , Nicolas E. Buchler

The study of the noise induced effects on the dynamics of a chain molecule crossing a potential barrier, in the presence of a metastable state, is presented. A two-dimensional stochastic version of the Rouse model for a flexible polymer has…

Statistical Mechanics · Physics 2015-05-13 N. Pizzolato , A. Fiasconaro , B. Spagnolo

Ring topologies of repressing genes have qualitatively different long-term dynamics if the number of genes is odd (they oscillate) or even (they exhibit bistability). However, these attractors may not fully explain the observed behavior in…

Molecular Networks · Quantitative Biology 2010-01-22 Natalja Strelkowa , Mauricio Barahona

First return maps of interspike intervals for biological neurons that generate repetitive bursts of impulses can display stereotyped structures (neuronal signatures). Such structures have been linked to the possibility of multicoding and…

Neurons and Cognition · Quantitative Biology 2015-06-22 Bóris Marin , Reynaldo Daniel Pinto , Robert C Elson , Eduardo Colli

We analyse the effect of intrinsic fluctuations on the properties of bistable stochastic systems with time scale separation operating under1 quasi-steady state conditions. We first formulate a stochastic generalisation of the quasi-steady…

Biological Physics · Physics 2016-03-02 Roberto de la Cruz , Pilar Guerrero , Fabian Spill , Tomás Alarcón

In biochemical signaling, information is often encoded in oscillatory signals. However, the advantages of such a coding strategy over an amplitude encoding scheme of constant signals remain unclear. Here we study the dynamics of a simple…

Subcellular Processes · Quantitative Biology 2012-03-09 Filipe Tostevin , Wiet de Ronde , Pieter Rein ten Wolde

Gene regulatory circuits show significant stochastic fluctuations in their circuit signals due to the low copy number of transcription factors. When a gene circuit component is connected to an existing circuit, the dynamic properties of the…

Quantitative Methods · Quantitative Biology 2009-10-30 Kyung Hyuk Kim , Herbert M. Sauro

Cooperative effects of periodic force and noise in globally Cooperative effects of periodic force and noise in globally coupled systems are studied using a nonlinear diffusion equation for the number density. The amplitude of the order…

Chaotic Dynamics · Physics 2009-11-07 Hidetsugu Sakaguchi

We propose a paradigmatic model system, a subcritical Hopf normal form subjected to noise and time-delayed feedback, to investigate the impact of time delay on coherence resonance in non-excitable systems. We develop analytical tools to…

Adaptation and Self-Organizing Systems · Physics 2014-12-08 Paul M. Geffert , Anna Zakharova , Andrea Vüllings , Wolfram Just , Eckehard Schöll

Biological rhythms are generated by pacemaker organs, such as the heart pacemaker organ (the sinoatrial node) and the master clock of the circadian rhythms (the suprachiasmatic nucleus), which are composed of a network of autonomously…

Cell Behavior · Quantitative Biology 2016-08-23 Hiroshi Kori , Yoji Kawamura , Naoki Masuda

We investigate the behavior of the residence times density function for different nonlinear dynamical systems with limit cycle behavior and perturbed parametrically with a colored noise. We present evidence that underlying the stochastic…

chao-dyn · Physics 2009-10-31 Juan L. Cabrera , J. Gorro~nogoitia , F. J. de la Rubia

Collective actuation describes the spontaneous synchronized oscillations taking place in active solids, when the elasto-active feedback, that generically couples the reorientation of the active forces and the elastic stress, is large…

Soft Condensed Matter · Physics 2024-02-27 Paul Baconnier , Vincent Démery , Olivier Dauchot

We have analyzed the interplay between noise and periodic spatial modulations in bistable systems outside equilibrium and found that noise is able to increase the spatial order of the system, giving rise to periodic patterns which otherwise…

Statistical Mechanics · Physics 2016-08-15 J. M. G. Vilar , J. M. Rubí

We introduce an extension to the standard reduction of oscillatory systems to a single phase variable. The standard reduction is often insufficient, particularly when the oscillations have variable amplitude and the magnitude of each…

Neurons and Cognition · Quantitative Biology 2024-11-12 Avinash J. Karamchandani

The analysis of a birhythmic modified van der Pol type oscillator driven by periodic excitation and L\`evy noise shows the possible occurrence of coherence resonance and stochastic resonance. The frequency of the harmonic excitation in the…

Adaptation and Self-Organizing Systems · Physics 2021-01-14 R. Mbakob Yonkeu , R. Yamapi , G. Filatrella , J. Kurths