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We present a model for the dynamics of a population of bacteria with a continuum of traits, who compete for resources and exchange horizontally (transfer) an otherwise vertically inherited trait with possible mutations. Competition…

Probability · Mathematics 2017-07-27 Sylvain Billiard , Pierre Collet , Régis Ferrière , Sylvie Méléard , Viet Chi Tran

We are interested in modeling some two-level population dynamics, resulting from the interplay of ecological interactions and phenotypic variation of individuals (or hosts) and the evolution of cells (or parasites) of two types living in…

Probability · Mathematics 2011-01-21 Sylvie Méléard , Sylvie Roelly

A microscopic agent dynamical model for diploid age-structured populations is used to study evolution of polymorphism and sympatric speciation. The underlying ecology is represented by a unimodal distribution of resources of some width.…

Populations and Evolution · Quantitative Biology 2015-06-26 E. Brigatti , J. S. Sa' Martins , I. Roditi

We propose and solve a Hamiltonian model for multidimensional epistastatic interactions between beneficial mutations. The model is able to give rise either to a phase transition between two equilibrium states, without any coexistence, or…

Biological Physics · Physics 2015-06-26 Seher Ozcelik , Ayse Erzan

In the presence of persistent payoff heterogeneity, the evolution of the aggregate strategy hugely depends on the underlying strategy composition under many evolutionary dynamics, while the aggregate dynamic under the standard BRD reduces…

Computer Science and Game Theory · Computer Science 2018-11-01 Dai Zusai

Exploiting the mathematical curiosity of intransitive dice, we present a simple theoretical model for co-evolution that captures scales ranging from the genome of the individual to the system-wide emergence of species diversity. We study a…

Populations and Evolution · Quantitative Biology 2022-12-02 Julius B. Kirkegaard , Kim Sneppen

Predicting fitness of biologically-active populations, communities or systems in fluctuating environments is a long-standing challenge. Phenotypic plasticity and bet-hedging strategy, two key evolutionary traits living systems harness to…

Populations and Evolution · Quantitative Biology 2024-10-24 Sumana Bhattacharyya , Uttam Singh , Anupam Sengupta

We are interested in modeling the Darwinian evolution resulting from the interplay of phenotypic variation and natural selection through ecological interactions, in the specific scales of the biological framework of adaptive dynamics.…

Probability · Mathematics 2013-02-05 Nicolas Champagnat , Pierre-Emmanuel Jabin , Sylvie Méléard

Biological organisms have to cope with stochastic variations in both the external environment and the internal population dynamics. Theoretical studies and laboratory experiments suggest that population diversification could be an effective…

Populations and Evolution · Quantitative Biology 2017-09-13 BingKan Xue , Stanislas Leibler

A theoretical and experimental analysis is made of the effects of self-adaptation in a simple evolving system. Specifically, we consider the effects of coding the mutation and crossover probabilities of a genetic algorithm evolving in…

adap-org · Physics 2008-02-03 C. Stephens , I. Garcia , J. Mora , H. Waelbroeck

Deterministic continuum models formulated in terms of non-local partial differential equations for the evolutionary dynamics of populations structured by phenotypic traits have been used recently to address open questions concerning the…

Populations and Evolution · Quantitative Biology 2020-10-14 Aleksandra Ardaševa , Robert A. Gatenby , Alexander R. A. Anderson , Helen M. Byrne , Philip K. Maini , Tommaso Lorenzi

Evolution is a dynamic process. The two classical forces of evolution are mutation and selection. Assuming small mutation rates, evolution can be predicted based solely on the fitness differences between phenotypes. Predicting an…

Populations and Evolution · Quantitative Biology 2015-03-23 Benedikt Bauer , Chaitanya S. Gokhale

We study a stochastic differential equation driven by a Poisson point process, which models continuous changes in a population's environment, as well as the stochastic fixation of beneficial mutations that might compensate for this change.…

Probability · Mathematics 2017-07-21 Elma Nassar , Etienne Pardoux

Most of the DNA that composes a complex organism is non-coding and defined as junk. Even the coding part is composed of genes that affect the phenotype differently. Therefore, a random mutation has an effect on the specimen fitness that…

Populations and Evolution · Quantitative Biology 2021-07-19 Mattia Miotto , Lorenzo Monacelli

Evolutionary competition often occurs simultaneously at multiple levels of organization, in which traits or behaviors that are costly for an individual can provide collective benefits to groups to which the individual belongs. Building off…

Populations and Evolution · Quantitative Biology 2024-11-14 Konstantinos Alexiou , Daniel B. Cooney

In complex systems, the interplay between nonlinear and stochastic dynamics, e.g., J. Monod's necessity and chance, gives rise to an evolutionary process in Darwinian sense, in terms of discrete jumps among attractors, with punctuated…

Adaptation and Self-Organizing Systems · Physics 2013-03-18 Hong Qian

The unwelcome evolution of malignancy during cancer progression emerges through a selection process in a complex heterogeneous population structure. In the present work, we investigate evolutionary dynamics in a phenotypically heterogeneous…

Populations and Evolution · Quantitative Biology 2018-02-07 Ali Mahdipour Shirayeh , Kamran Kaveh , Mohammad Kohandel , Siv Sivaloganathan

As pathogens spread in a population of hosts, immunity is built up and the pool of susceptible individuals is depleted. This generates selective pressure, to which many human RNA viruses, such as influenza virus or SARS-CoV-2, respond with…

Populations and Evolution · Quantitative Biology 2024-08-29 Pierre Barrat-Charlaix , Richard A. Neher

Mathematical modelling of epidemiological and coevolutionary dynamics is widely being used to improve disease management strategies of infectious diseases. Many diseases present some form of intra-host quiescent stage, also known as covert…

Populations and Evolution · Quantitative Biology 2022-05-26 Usman Sanusi , Sona John , Johannes Mueller , Aurélien Tellier

Populations of replicating entities frequently experience sudden or cyclical changes in environment. We explore the implications of this phenomenon via a environmental switching parameter in several common evolutionary dynamics models…

Dynamical Systems · Mathematics 2013-06-12 Marc Harper , Dashiell Fryer , Andrew Vlasic