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Related papers: Necrotic tumor growth: an analytic approach

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In this paper we consider two diffuse interface models for tumor growth coupling a Cahn-Hilliard type equation for the tumor phase parameter to a reaction-diffusion type equation for the nutrient. The models are distinguished by the…

Analysis of PDEs · Mathematics 2024-07-31 Filippo Riva , Elisabetta Rocca

We introduce here a new diffuse interface thermodynamically consistent non-isothermal model for tumor growth in presence of a nutrient in a domain $\Omega \subset \mathbb{R}^3$. In particular our system describes the growth of a tumor…

Analysis of PDEs · Mathematics 2022-12-19 Erica Ipocoana

In this paper, we consider an age-structured mechanical model for tumor growth. This model takes into account the life-cycle of tumor cells by including an age variable. The underlying process for tumor growth is the same as classical tumor…

Analysis of PDEs · Mathematics 2026-03-05 Maeve Wildes

The inverse geometric approach to the modeling of the growth of circular objects revealing required features, such as the velocity of the growth and fractal behavior of their contours, is presented. It enables to reproduce some of the…

Medical Physics · Physics 2007-05-23 Branislav Brutovsky , Denis Horvath , Vladimir Lisy

We propose a diffuse interface model to describe tumor as a multicomponent deformable porous medium. We include mechanical effects in the model by coupling the mass balance equations for the tumor species and the nutrient dynamics to a…

Analysis of PDEs · Mathematics 2021-09-23 Pavel Krejci , Elisabetta Rocca , Juergen Sprekels

In this paper, we study a tumor growth model with nutrients. The contact inhibition for the tumor cells, presented in the model, results in the evolution of a congested tumor patch. We study the regularity of the tumor patch as the…

Analysis of PDEs · Mathematics 2022-12-01 Inwon Kim , Jona Lelmi

We develop a field theory-inspired stochastic model for description of tumour growth based on an analogy with an SI epidemic model, where the susceptible individuals (S) would represent the healthy cells and the infected ones (I), the…

Biological Physics · Physics 2017-05-30 Leonardo Mondaini

We consider a free boundary problem for a system of PDEs, modeling the growth of a biological tissue. A morphogen, controlling volume growth, is produced by specific cells and then diffused and absorbed throughout the domain. The geometric…

Analysis of PDEs · Mathematics 2017-11-22 Alberto Bressan , Marta Lewicka

The problem of tumor growth prediction is challenging, but promising results have been achieved with both model-driven and statistical methods. In this work, we present a framework for the evaluation of growth predictions that focuses on…

We consider a free boundary tumor model under the presence of angiogenesis and time delays in the process of proliferation, in which the cell location is incorporated. It is assumed that the tumor attracts blood vessels at a rate…

Analysis of PDEs · Mathematics 2021-03-09 Zejia Wang , Haihua Zhou , Huijuan Song

The epitaxial growth process of a high symmetry surface occurs because adatoms meet and nucleate new islands, that eventually coalesce and complete atomic layers. During multilayer growth, nucleation usually takes place on top of terraces…

Statistical Mechanics · Physics 2007-05-23 Paolo Politi , Claudio Castellano

In this manuscript, we study a nonlinear model of tumor growth, described by a coupled hyperbolic-elliptic system of partial differential equations. In this model, the compressible flow of tumor cells is modeled by a transport equation for…

Analysis of PDEs · Mathematics 2025-08-27 Jeffrey Kuan , Konstantina Trivisa

In this paper we study the discrete coagulation--fragmentation models with growth, decay and sedimentation. We demonstrate the existence and uniqueness of classical global solutions provided the linear processes are sufficiently strong.…

Dynamical Systems · Mathematics 2018-09-05 Jacek Banasiak , Luke O. Joel , Sergey Shindin

Theoretical and computational tools that can be used in the clinic to predict neoplastic progression and propose individualized optimal treatment strategies to control cancer growth is desired. To develop such a predictive model, one must…

Cell Behavior · Quantitative Biology 2015-05-20 Salvatore Torquato

In this work, we consider a diffuse interface model for tumour growth in the presence of a nutrient which is consumed by the tumour. The system of equations consists of a Cahn--Hilliard equation with source terms for the tumour cells and a…

Numerical Analysis · Mathematics 2022-05-09 Harald Garcke , Dennis Trautwein

This paper studies an evolving bulk--surface finite element method for a model of tissue growth, which is a modification of the model of Eyles, King and Styles (2019). The model couples a Poisson equation on the domain with a forced mean…

Numerical Analysis · Mathematics 2024-01-18 Dominik Edelmann , Balázs Kovács , Christian Lubich

A free boundary problem describing small deformations in a membrane based model of electrostatically actuated MEMS is investigated. The existence of stationary solutions is established for small voltage values. A justification of the widely…

Analysis of PDEs · Mathematics 2013-01-28 Philippe Laurencot , Christoph Walker

In this paper we study a tumor growth model with nutrients. The model presents dynamic patch solutions due to the contact inhibition among the tumor cells. We show that when the nutrients do not diffuse and the cells do not die, the tumor…

Analysis of PDEs · Mathematics 2022-04-18 Matt Jacobs , Inwon Kim , Jiajun Tong

We formulate a Hele-Shaw type free boundary problem for a tumor growing under the combined effects of pressure forces, cell multiplication and active motion, the latter being the novelty of the present paper. This new ingredient is…

Analysis of PDEs · Mathematics 2014-01-14 Benoît Perthame , Fernando Quirós , Min Tang , Nicolas Vauchelet

For a singularly perturbed system of reaction--diffusion equations, assuming that the 0th order solutions in regular and singular regions are all stable, we construct matched asymptotic expansions for formal solutions to any desired order…

patt-sol · Physics 2008-02-03 Xiao-Biao Lin