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We present BioLunar, developed using the Lunar framework, as a tool for supporting biological analyses, with a particular emphasis on molecular-level evidence enrichment for biomarker discovery in oncology. The platform integrates Large…

Inferring topics from the overwhelming amount of short texts becomes a critical but challenging task for many content analysis tasks, such as content charactering, user interest profiling, and emerging topic detecting. Existing methods such…

Computation and Language · Computer Science 2016-09-28 Jipeng Qiang , Ping Chen , Tong Wang , Xindong Wu

We present a scalable, AI-powered system that identifies and extracts evidence-based behavioral nudges from unstructured biomedical literature. Nudges are subtle, non-coercive interventions that influence behavior without limiting choice,…

Several interdisciplinary areas have appeared at the interface between biological and physical sciences. In this work, we suggest a complex network-based methodology for analyzing the interrelationships between some of these…

Digital Libraries · Computer Science 2019-05-10 Paulo E. P. Burke , Luciano da F. Costa

Identifying molecular signatures from complex disease patients with underlying symptomatic similarities is a significant challenge in the analysis of high dimensional multi-omics data. Topological data analysis (TDA) provides a way of…

Genomics · Quantitative Biology 2024-04-23 Davide Gurnari , Aldo Guzmán-Sáenz , Filippo Utro , Aritra Bose , Saugata Basu , Laxmi Parida

In this paper, we provide the first practical algorithms with provable guarantees for the problem of inferring the topics assigned to each document in an LDA topic model. This is the primary inference problem for many applications of topic…

Machine Learning · Computer Science 2025-06-10 Adam Breuer

Standard LDA model suffers the problem that the topic assignment of each word is independent and word correlation hence is neglected. To address this problem, in this paper, we propose a model called Word Related Latent Dirichlet Allocation…

Computation and Language · Computer Science 2014-11-11 Xun Wang

The best evidence concerning comparative treatment effectiveness comes from clinical trials, the results of which are reported in unstructured articles. Medical experts must manually extract information from articles to inform…

Computation and Language · Computer Science 2022-01-11 Benjamin E. Nye , Jay DeYoung , Eric Lehman , Ani Nenkova , Iain J. Marshall , Byron C. Wallace

Citations in scholarly work serve the essential purpose of acknowledging and crediting the original sources of knowledge that have been incorporated or referenced. Depending on their surrounding textual context, these citations are used for…

Digital Libraries · Computer Science 2023-09-19 Yang Zhang , Yufei Wang , Kai Wang , Quan Z. Sheng , Lina Yao , Adnan Mahmood , Wei Emma Zhang , Rongying Zhao

Current research in biology heavily depends on the availability and efficient use of information. In order to build new knowledge, various sources of biological data must often be combined. Semantic Web technologies, which provide a common…

Quantitative Methods · Quantitative Biology 2009-02-19 Claude Pasquier

Gene/protein interactions provide critical information for a thorough understanding of cellular processes. Recently, considerable interest and effort has been focused on the construction and analysis of genome-wide gene networks. The large…

Molecular Networks · Quantitative Biology 2022-04-25 Xin Li , Hsinchun Chen , Zan Huang , Hua Su , Jesse D. Martinez

Topic evolution modeling has received significant attentions in recent decades. Although various topic evolution models have been proposed, most studies focus on the single document corpus. However in practice, we can easily access data…

Computation and Language · Computer Science 2021-11-23 Yandi Zhu , Xiaoling Lu , Jingya Hong , Feifei Wang

In Biomedical Natural Language Processing (BioNLP) tasks, such as Relation Extraction, Named Entity Recognition, and Text Classification, the scarcity of high-quality data remains a significant challenge. This limitation poisons large…

Computation and Language · Computer Science 2025-04-01 Zhengyi Zhao , Shubo Zhang , Bin Liang , Binyang Li , Kam-Fai Wong

Scientific names of organisms consist of a genus name and a species epithet, with the latter often reflecting aspects such as morphology, ecology, distribution, and cultural background. Traditionally, researchers have manually labeled…

Computation and Language · Computer Science 2026-01-13 Keito Inoshita , Kota Nojiri , Haruto Sugeno , Takumi Taga

Machine learning is a modern approach to problem-solving and task automation. In particular, machine learning is concerned with the development and applications of algorithms that can recognize patterns in data and use them for predictive…

To retrieve and compare scientific data of simulations and experiments in materials science, data needs to be easily accessible and machine readable to qualify and quantify various materials science phenomena. The recent progress in open…

Materials Science · Physics 2025-03-25 Balduin Katzer , Steffen Klinder , Katrin Schulz

Large Language Models (LLMs) show promise in biomedicine but lack true causal understanding, relying instead on correlations. This paper envisions causal LLM agents that integrate multimodal data (text, images, genomics, etc.) and perform…

Artificial Intelligence · Computer Science 2025-05-23 Adib Bazgir , Amir Habibdoust Lafmajani , Yuwen Zhang

Ever-expanding volumes of biomedical text require automated semantic annotation techniques to curate and put to best use. An established field of research seeks to link mentions in text to knowledge bases such as those included in the UMLS…

Artificial Intelligence · Computer Science 2018-11-13 Genevieve Gorrell , Xingyi Song , Angus Roberts

Topic modeling, a method for extracting the underlying themes from a collection of documents, is an increasingly important component of the design of intelligent systems enabling the sense-making of highly dynamic and diverse streams of…

Information Retrieval · Computer Science 2019-10-07 Chris Gropp , Alexander Herzog , Ilya Safro , Paul W. Wilson , Amy W. Apon

Everyday we increasingly rely on machine learning models to automate and support high-stake tasks and decisions. This growing presence means that humans are now constantly interacting with machine learning-based systems, training and using…

Machine Learning · Computer Science 2026-04-21 Clara Punzi , Roberto Pellungrini , Mattia Setzu , Fosca Giannotti , Dino Pedreschi