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Thematic analysis (TA) is a widely used qualitative approach for uncovering latent meanings in unstructured text data. TA provides valuable insights in healthcare but is resource-intensive. Large Language Models (LLMs) have been introduced…

Human-Computer Interaction · Computer Science 2025-03-27 Huimin Xu , Seungjun Yi , Terence Lim , Jiawei Xu , Andrew Well , Carlos Mery , Aidong Zhang , Yuji Zhang , Heng Ji , Keshav Pingali , Yan Leng , Ying Ding

miRNA mRNA relations are closely linked to several biological processes and disease mechanisms In a recent study we tested the performance of large language models LLMs on extracting miRNA mRNA relations from PubMed PubMedBERT achieved the…

Many natural phenomena are intrinsically causal. The discovery of the cause-effect relationships implicit in these processes can help us to understand and describe them more effectively, which boils down to causal discovery about the data…

Quantitative Methods · Quantitative Biology 2024-01-09 Jean Pierre Gomez

Given the remarkable performance of Large Language Models (LLMs), an important question arises: Can LLMs conduct human-like scientific research and discover new knowledge, and act as an AI scientist? Scientific discovery is an iterative…

Machine Learning · Computer Science 2025-02-24 Tingting Chen , Srinivas Anumasa , Beibei Lin , Vedant Shah , Anirudh Goyal , Dianbo Liu

Given that observational and numerical climate data are being produced at ever more prodigious rates, increasingly sophisticated and automated analysis techniques have become essential. Deep learning is quickly becoming a standard approach…

Fluid Dynamics · Physics 2017-09-12 A. Rupe , J. P. Crutchfield , K. Kashinath , Prabhat

Search systems are often focused on providing relevant results for the "now", assuming both corpora and user needs that focus on the present. However, many corpora today reflect significant longitudinal collections ranging from 20 years of…

Computation and Language · Computer Science 2017-08-01 Guy D. Rosin , Eytan Adar , Kira Radinsky

We introduce an explainability method for biomedical hypothesis generation systems, built on top of the novel Hypothesis Generation Context Retriever framework. Our approach combines semantic graph-based retrieval and relevant…

Information Retrieval · Computer Science 2025-11-11 Ilya Tyagin , Saeideh Valipour , Aliaksandra Sikirzhytskaya , Michael Shtutman , Ilya Safro

Large language models (LLMs) have reshaped the research landscape by enabling new approaches to knowledge retrieval and creative ideation. Yet their application in discipline-specific experimental science, particularly in highly…

Machine Learning · Computer Science 2025-08-12 Rachel K. Luu , Jingyu Deng , Mohammed Shahrudin Ibrahim , Nam-Joon Cho , Ming Dao , Subra Suresh , Markus J. Buehler

Data discovery in data lakes with ever increasing datasets has long been recognized as a big challenge in the realm of data management, especially for semantic search of and hierarchical global catalog generation of tables. While large…

Databases · Computer Science 2025-02-24 Qi An , Chihua Ying , Yuqing Zhu , Yihao Xu , Manwei Zhang , Jianmin Wang

In recent decades, traditional drug research and development have been facing challenges such as high cost, long timelines, and high risks. To address these issues, many computational approaches have been suggested for predicting the…

Quantitative Methods · Quantitative Biology 2023-09-13 Chunyan Ao , Zhichao Xiao , Lixin Guan , Liang Yu

The objective of advanced topic modeling is not only to explore latent topical structures, but also to estimate relationships between the discovered topics and theoretically relevant metadata. Methods used to estimate such relationships…

Computation and Language · Computer Science 2025-04-29 P. Schulze , S. Wiegrebe , P. W. Thurner , C. Heumann , M. Aßenmacher

Recent advances in large language models (LLMs) have made significant progress across multiple biomedical tasks, including biomedical question answering, lay-language summarization of the biomedical literature, and clinical note…

Information Retrieval · Computer Science 2026-03-24 Deepak Gupta , Dina Demner-Fushman , William Hersh , Steven Bedrick , Kirk Roberts

Being an unsupervised machine learning and data mining technique, biclustering and its multimodal extensions are becoming popular tools for analysing object-attribute data in different domains. Apart from conventional clustering techniques,…

Artificial Intelligence · Computer Science 2017-02-20 Dmitry I. Ignatov , Bruce W. Watson

Recent advancements in Large Language Models (LLMs) are transforming biology, computer science, engineering, and every day life. However, integrating the wide array of computational tools, databases, and scientific literature continues to…

Biological organisms are composed of numerous interconnected biochemical processes. Diseases occur when normal functionality of these processes is disrupted. Thus, understanding these biochemical processes and their interrelationships is a…

Artificial Intelligence · Computer Science 2014-03-04 Saadat Anwar

Living systems are subject to the arrow of time; from birth, they undergo complex transformations (self-organization) in a constant battle for survival, but inevitably ageing and disease trap them to death. Can ageing be understood and…

Other Quantitative Biology · Quantitative Biology 2020-08-21 Tamàs Fülöp , Mathieu Desroches , Fernando Antônio Nóbrega Santos , Serafim Rodrigues

This study introduces Bidirectional Topic Matching (BTM), a novel method for cross-corpus topic modeling that quantifies thematic overlap and divergence between corpora. BTM is a flexible framework that can incorporate various topic…

Computation and Language · Computer Science 2024-12-25 Raven Adam , Marie Lisa Kogler

This comprehensive survey delves into the latest advancements in Relation Extraction (RE), a pivotal task in natural language processing essential for applications across biomedical, financial, and legal sectors. This study highlights the…

Computation and Language · Computer Science 2025-07-03 Jose A. Diaz-Garcia , Julio Amador Diaz Lopez

Within the past few decades we have witnessed digital revolution, which moved scholarly communication to electronic media and also resulted in a substantial increase in its volume. Nowadays keeping track with the latest scientific…

Digital Libraries · Computer Science 2017-10-30 Dominika Tkaczyk

Topological data analysis (TDA) is an active field of mathematics for quantifying shape in complex data. Standard methods in TDA such as persistent homology (PH) are typically focused on the analysis of data consisting of a single entity…

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