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This research paper discusses the advances made in the past decade in biomedicine and Large Language Models. To understand how the advances have been made hand-in-hand with one another, the paper also discusses the integration of Natural…

Computation and Language · Computer Science 2024-06-26 Michael Ackerman

Literature-based discovery (LBD) aims to discover valuable latent relationships between disparate sets of literatures. This paper presents the first inclusive scientometric overview of LBD research. We utilize a comprehensive scientometric…

Digital Libraries · Computer Science 2020-12-01 Andrej Kastrin , Dimitar Hristovski

Identification of disease genes, which are a set of genes associated with a disease, plays an important role in understanding and curing diseases. In this paper, we present a biomedical knowledge graph designed specifically for this…

Topics models, such as LDA, are widely used in Natural Language Processing. Making their output interpretable is an important area of research with applications to areas such as the enhancement of exploratory search interfaces and the…

Computation and Language · Computer Science 2019-04-01 Areej Alokaili , Nikolaos Aletras , Mark Stevenson

Objective: To develop a high-throughput biomedical relation extraction system that takes advantage of the large language models'(LLMs) reading comprehension ability and biomedical world knowledge in a scalable and evidential manner.…

Computation and Language · Computer Science 2024-03-27 Songchi Zhou , Sheng Yu

Topic modeling is one of the most powerful techniques in text mining for data mining, latent data discovery, and finding relationships among data, text documents. Researchers have published many articles in the field of topic modeling and…

Information Retrieval · Computer Science 2018-12-07 Hamed Jelodar , Yongli Wang , Chi Yuan , Xia Feng , Xiahui Jiang , Yanchao Li , Liang Zhao

The discovery of causal relationships from high-dimensional data is a major open problem in bioinformatics. Machine learning and feature attribution models have shown great promise in this context but lack causal interpretation. Here, we…

Machine Learning · Computer Science 2023-04-26 Payam Dibaeinia , Saurabh Sinha

Social scientists employ latent Dirichlet allocation (LDA) to find highly specific topics in large corpora, but they often struggle in this task because (1) LDA, in general, takes a significant amount of time to fit on large corpora; (2)…

Methodology · Statistics 2025-12-23 Kohei Watanabe

Relation extraction is a fundamental problem in natural language processing. Most existing models are defined for relation extraction in the general domain. However, their performance on specific domains (e.g., biomedicine) is yet unclear.…

Computation and Language · Computer Science 2021-12-14 Yongkang Li

Large language models (LLMs) have grown in their usage to provide support for question answering across numerous disciplines. The models on their own have already shown promise for answering basic questions, however fail quickly where…

Information Retrieval · Computer Science 2025-04-15 David Brett , Anniek Myatt

Rapid advancements in imaging techniques and analytical methods over the past decade have revolutionized our ability to comprehensively probe the biological world at multiple scales, pinpointing the type, quantity, location, and even…

Artificial Intelligence · Computer Science 2025-10-02 Shanghang Zhang , Gaole Dai , Tiejun Huang , Jianxu Chen

Extracting and identifying latent topics in large text corpora has gained increasing importance in Natural Language Processing (NLP). Most models, whether probabilistic models similar to Latent Dirichlet Allocation (LDA) or neural topic…

Computation and Language · Computer Science 2023-03-31 Anton Thielmann , Quentin Seifert , Arik Reuter , Elisabeth Bergherr , Benjamin Säfken

With the large volume of unstructured data that increases constantly on the web, the motivation of representing the knowledge in this data in the machine-understandable form is increased. Ontology is one of the major cornerstones of…

Computation and Language · Computer Science 2021-05-10 Fatima N. AL-Aswadi , Huah Yong Chan , Keng Hoon Gan

Many data we collect today are in tabular form, with rows as records and columns as attributes associated with each record. Understanding the structural relationship in tabular data can greatly facilitate the data science process.…

Data Structures and Algorithms · Computer Science 2020-09-09 Jin Cao , Yibo Zhao , Linjun Zhang , Jason Li

Biomedical Information Extraction is an exciting field at the crossroads of Natural Language Processing, Biology and Medicine. It encompasses a variety of different tasks that require application of state-of-the-art NLP techniques, such as…

Computation and Language · Computer Science 2017-05-17 Surag Nair

The correlation and interactions among different biological entities comprise the biological system. Although already revealed interactions contribute to the understanding of different existing systems, researchers face many questions…

Information Retrieval · Computer Science 2014-01-14 Md. Naseef-Ur-Rahman Chowdhury , Suvankar Paul , Kazi Zakia Sultana

In the real world, many topics are inter-correlated, making it challenging to investigate their structure and relationships. Understanding the interplay between topics and their relevance can provide valuable insights for researchers,…

Applications · Statistics 2024-02-01 Yeseul Jeon , Jina Park , Ick Hoon Jin , Dongjun Chungc

One of the main computational and scientific challenges in the modern age is to extract useful information from unstructured texts. Topic models are one popular machine-learning approach which infers the latent topical structure of a…

Machine Learning · Statistics 2018-07-20 Martin Gerlach , Tiago P. Peixoto , Eduardo G. Altmann

With the advent of artificial intelligence (AI), many researchers are attempting to extract structured information from document-level biomedical literature by fine-tuning large language models (LLMs). However, they face significant…

Neural and Evolutionary Computing · Computer Science 2026-02-26 Lei Zhao , Ling Kang , Quan Guo

Due to the exponential growth of biomedical literature, event and relation extraction are important tasks in biomedical text mining. Most work only focus on relation extraction, and detect a single entity pair mention on a short span of…

Computation and Language · Computer Science 2020-05-08 Elaheh ShafieiBavani , Antonio Jimeno Yepes , Xu Zhong , David Martinez Iraola