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Related papers: Stability of Boolean and continuous dynamics

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Bistable biological regulatory systems need to cope with stochastic noise to fine-tune their function close to bifurcation points. Here, we study stability properties of this regime in generic systems to demonstrate that cooperative…

Adaptation and Self-Organizing Systems · Physics 2025-08-04 Daniele Proverbio , Arthur N. Montanari , Alexander Skupin , Jorge Gonçalves

Random Boolean networks have been used widely to explore aspects of gene regulatory networks. A modified form of the model through which to systematically explore the effects of increasing the number of gene states has previously been…

Molecular Networks · Quantitative Biology 2023-02-06 Larry Bull

Computational models of biological processes provide one of the most powerful methods for a detailed analysis of the mechanisms that drive the behavior of complex systems. Logic-based modeling has enhanced our understanding and…

Molecular Networks · Quantitative Biology 2022-02-08 John Zobolas , Pedro T. Monteiro , Martin Kuiper , Åsmund Flobak

Canalization is a classic concept in Developmental Biology that is thought to be an important feature of evolving systems. In a Boolean network it is a form of network robustness in which a subset of the input signals control the behavior…

Molecular Networks · Quantitative Biology 2015-05-28 Matthew D. Reichl , Kevin E. Bassler

Interactions between genes and gene products give rise to complex circuits that enable cells to process information and respond to external signals. Theoretical studies often describe these interactions using continuous, stochastic, or…

Molecular Networks · Quantitative Biology 2007-05-23 Madalena Chaves , Reka Albert , Eduardo D. Sontag

In many large systems, such as those encountered in biology or economics, the dynamics are nonlinear and are only known very coarsely. It is often the case, however, that the signs (excitation or inhibition) of individual interactions are…

Systems and Control · Computer Science 2016-03-22 Marco Tulio Angulo , Jean-Jacques Slotine

Using extensive particle-based simulations, we investigate out-of-equilibrium pattern dynamics in an oppositely driven binary particle system in two dimensions. A surprisingly rich dynamical behavior including lane formation, jamming,…

Soft Condensed Matter · Physics 2015-06-05 Masahiro Ikeda , Hirofumi Wada , Hisao Hayakawa

We study the emergence of typicality in classical systems with a large number of binary state variables. We show analytically that for sufficiently large subsets of the complete state space, state functions which can be associated with…

Statistical Mechanics · Physics 2025-03-12 Nicolas Nessi

Statistical models provide a powerful and useful class of approximations for calculating reaction rates by bypassing the need for detailed, and often difficult, dynamical considerations. Such approaches invariably invoke specific…

Chemical Physics · Physics 2020-04-01 Sourav Karmakar , Pankaj Kumar Yadav , Srihari Keshavamurthy

We study experimentally the synchronization patterns in time-delayed directed Boolean networks of excitable systems. We observe a transition in the network dynamics when the refractory time of the individual systems is adjusted. When the…

Adaptation and Self-Organizing Systems · Physics 2013-03-07 David P. Rosin , Damien Rontani , Daniel J. Gauthier , Eckehard Schöll

This paper investigates the stability properties of a nonlinear fractional differential equation with two discrete delays and a delay-dependent coefficient. Such equations arise in various biological and control systems where temporal…

Dynamical Systems · Mathematics 2026-03-12 Pragati Dutta , Sachin Bhalekar

Low-dimensional yet rich dynamics often emerge in the brain. Examples include oscillations and chaotic dynamics during sleep, epilepsy, and voluntary movement. However, a general mechanism for the emergence of low dimensional dynamics…

Neurons and Cognition · Quantitative Biology 2018-08-29 Wilten Nicola , Peter Hellyer , Sue Ann Campbell , Claudia Clopath

Limit theorems for a linear dynamical system with random interactions are established. These theorems enable us to characterize the dynamics of a large complex system in details and assess whether a large complex system is stable or…

Mathematical Physics · Physics 2011-11-10 J. F. Feng , M. Shcherbina , B. Tirozzi

The nonstationary dynamics of topological solitons (dislocations, domain walls, fluxons) and their bound states in one-dimensional systems with high dispersion are investigated. Dynamical features of a moving kink emitting radiation and…

Pattern Formation and Solitons · Physics 2020-08-11 M. M. Bogdan , O. V. Charkina

Simple nonlinear dynamical systems with multiple stable stationary states are often taken as models for switchlike biological systems. This paper considers the interaction of multiple such simple multistable systems when they are embedded…

Quantitative Methods · Quantitative Biology 2008-04-10 Dennis Cates Wylie

Here we numerically study a model of excitable media, namely, a network with occasionally quiet nodes and connection weights that vary with activity on a short-time scale. Even in the absence of stimuli, this exhibits unstable dynamics,…

Disordered Systems and Neural Networks · Physics 2015-05-19 S. de Franciscis , J. J. Torres , J. Marro

Communication between cells is realized by exchange of biochemical substances. Due to internal organization of living systems and variability of external parameters, the exchange is heavily influenced by perturbations of various parameters…

Chaotic Dynamics · Physics 2015-05-19 Dragutin T. Mihailovic , Igor Balaz

Biochemical reaction networks are subjected to large fluctuations attributable to small molecule numbers, yet underlie reliable biological functions. Most theoretical approaches describe them as purely deterministic or stochastic dynamical…

Molecular Networks · Quantitative Biology 2013-06-11 Jingkui Wang , Marc Lefranc , Quentin Thommen

These lectures present results and problems on the characterization of structurally stable dynamics. We will shed light those which do not seem to depend on the regularity class (holomorphic or differentiable). Furthermore, we will present…

Dynamical Systems · Mathematics 2017-03-02 Pierre Berger

Dynamic perturbation equations are derived for a generic stationary state of an elastic string model -- of the kind appropriate for representing a superconducting cosmic string -- in a flat background. In the case of a circular equilibrium…

High Energy Physics - Theory · Physics 2009-11-10 Brandon Carter , Xavier Martin
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