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Particles interacting with short-ranged potentials have attracted increasing interest, partly for their ability to model mesoscale systems such as colloids interacting via DNA or depletion. We consider the free energy landscape of such…

Mathematical Physics · Physics 2015-06-11 Miranda Holmes-Cerfon , Steven J. Gortler , Michael P. Brenner

The Euler-Lagrange equation of the phase-field crystal (PFC) model has been solved under appropriate boundary conditions to obtain the equilibrium free energy of the body centered cubic crystal-liquid interface for 18 orientations at…

Materials Science · Physics 2014-06-20 Frigyes Podmaniczky , Gyula I. Tóth , Tamás Pusztai , László Gránásy

The Free Energy Principle (FEP) states that under suitable conditions of weak coupling, random dynamical systems with sufficient degrees of freedom will behave so as to minimize an upper bound, formalized as a variational free energy, on…

Quantum Physics · Physics 2022-07-21 Chris Fields , Karl Friston , James F. Glazebrook , Michael Levin

We discuss several general aspects of the free energy of the standard model at high temperatures. In particular the Clausius-Clapeyron equation is shown to yield a relation between the latent heat and the jump in the order parameter. The…

High Energy Physics - Phenomenology · Physics 2016-09-01 W. Buchmuller , Z. Fodor , A. Hebecker

Free energy landscapes encode the kinetics, intermediates, and transition states that govern molecular processes and are thus a key target of single biomolecule research. Typical approaches to deriving optimal, error-minimizing,…

Biological Physics · Physics 2025-11-25 Oliver Cheng , Zosia Adamska , Michael P. Brenner , Megan C. Engel

A key uncertainty in the design and development of magnetic confinement fusion energy reactors is predicting edge plasma turbulence. An essential step in overcoming this uncertainty is the validation in accuracy of reduced turbulent…

Plasma Physics · Physics 2022-05-20 Abhilash Mathews , Noah Mandell , Manaure Francisquez , Jerry Hughes , Ammar Hakim

We give a quantum version of the Jarzynski relation between the distribution of work done over a certain time-interval on a system and the difference of equilibrium free energies. The main new ingredient is the identification of work…

Condensed Matter · Physics 2015-05-26 Wojciech De Roeck , Christian Maes

In this paper, we consider Langevin processes with mechanical constraints. The latter are a fundamental tool in molecular dynamics simulation for sampling purposes and for the computation of free energy differences. The results of this…

Statistical Mechanics · Physics 2011-04-19 Tony Lelievre , Mathias Rousset , Gabriel Stoltz

We present fluctuation theorems and moment generating function equalities for generalized thermodynamic observables and quantum dynamics described by completely positive trace preserving (CPTP) maps, with and without feedback control. Our…

Quantum Physics · Physics 2013-10-01 Tameem Albash , Daniel A. Lidar , Milad Marvian , Paolo Zanardi

Conventionally defined free-energy landscape (FEL) exhibits unphysical dependence on the choice of reaction coordinates and hence lacks universal predictive ability. We here show that three physically plausible requirements uniquely…

Statistical Mechanics · Physics 2024-03-01 Takenobu Nakamura

The details of fluctuation free energy conservation in the gyrofluid model are examined. The polarisation equation relates ExB flow and eddy energy to combinations of the potential and the density and perpendicular temperature. These…

Plasma Physics · Physics 2009-09-29 Bruce D. Scott

We propose a method of free energy calculation for a system of interacting particles arranged in a Bravais lattice. It will be shown how to treat divergences for infinite unbounded systems with "catastrophic" potetntials like Coulomb and…

Statistical Mechanics · Physics 2015-07-17 B. I. Lev , V. B. Tymchyshyn , A. G. Zagorodny

The Free-Energy-Principle (FEP) is an influential and controversial theory which postulates a deep and powerful connection between the stochastic thermodynamics of self-organization and learning through variational inference. Specifically,…

Artificial Intelligence · Computer Science 2021-10-05 Beren Millidge , Anil Seth , Christopher L Buckley

A double-stranded DNA unravels thermally through intermediate denatured bubble segments. Intrinsically, fluctuations ensue at the bubble boundaries from non-equilibrium (NE) energy exchanges with the environment. However, such details gets…

Soft Condensed Matter · Physics 2018-09-21 Keren Jiang , Faheem Khan , Javix Thomas , Arindam Phani , Thomas Thundat

A free-energy functional that contains both the symmetry conserved and symmetry broken parts of the direct pair correlation function has been used to investigate the freezing of a system of hard spheres into crystalline and amorphous…

Soft Condensed Matter · Physics 2015-05-27 Swarn Lata Singh , Atul S. Bharadwaj , Yashwant Singh

The free energy of barium titanate is computed around the Curie temperature as a function of polarization from the first-principles derived effective hamiltonian of Zhong, Vanderbilt and Rabe [Phys. Rev. Lett. 73, 1861 (1994)], through…

Materials Science · Physics 2015-05-13 Gregory Geneste

We present a method to explore the free energy landscapes of chemical reactions with post-transition-state bifurcations using an enhanced sampling method based on well-tempered metadynamics. Obviating the need for computationally expensive…

Chemical Physics · Physics 2023-04-18 Juno Nam , YounJoon Jung

We consider the steady state of an open system in which there is a flux of matter between two reservoirs at different chemical potentials. For a large system of size $N$, the probability of any macroscopic density profile $\rho(x)$ is…

Statistical Mechanics · Physics 2009-11-07 B. Derrida , J. L. Lebowitz , E. R. Speer

Based on a true phase space probability distribution function and an ensemble averaging procedure we have recently developed [Phys. Rev. E 65, 021109 (2002)] a non-Markovian quantum Kramers' equation to derive the quantum rate coefficient…

Statistical Mechanics · Physics 2009-11-07 Dhruba Banerjee , Suman Kumar Banik , Bidhan Chandra Bag , Deb Shankar Ray

Alchemical free energy calculations are a useful tool for predicting free energy differences associated with the transfer of molecules from one environment to another. The hallmark of these methods is the use of "bridging" potential energy…

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