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Nuclear magnetism underpins areas such as medicine in magnetic resonance imaging (MRI). Hyperpolarization of nuclei enhances the quantity and quality of information that can be determined from these techniques by increasing their signal to…

Superconductivity · Physics 2025-01-16 John Z. Myers , Kai Buckenmaier , Andrey N. Pravdivtsev , Markus Plaumann , Rainer Körber

Nuclear Magnetic Resonance (NMR) is an intriguing quantum-mechanical effect that is used for daily life medical diagnostics and chemical analysis alike. Numerous advancements have contributed to the success of the technique, including…

Chemical Physics · Physics 2020-04-28 Andrey N. Pravdivtsev , Frank D. Sönnichsen , Jan-Bernd Hövener

We show that high-resolution NMR can reach picomole sensitivity for micromolar concentrations of analyte by combining parahydrogen induced hyperpolarisation (PHIP)with a high-sensitivity transmission line micro-detector. The para-enriched…

Chemical Physics · Physics 2019-05-20 James Eills , William Hale , Manvendra Sharma , Matheus Rossetto , Malcolm H. Levitt , Marcel Utz

As a complementary analysis tool to conventional high-field NMR, zero- to ultralow-field (ZULF) NMR detects nuclear magnetization signals in the sub-microtesla regime. Spin-exchange relaxation-free (SERF) atomic magnetometers provide a new…

Quantum Physics · Physics 2020-12-01 Min Jiang , Ji Bian , Qing Li , Ze Wu , Haowen Su , Minxiang Xu , Yuanhong Wang , Xin Wang , Xinhua Peng

Zero- to ultralow-field nuclear magnetic resonance (ZULF NMR) is an alternative spectroscopic method to high-field NMR, in which samples are studied in the absence of a large magnetic field. Unfortunately, there is a large barrier to entry…

Chemical Physics · Physics 2020-04-29 John W. Blanchard , Teng Wu , James Eills , Yinan Hu , Dmitry Budker

We review instrumentation for nuclear magnetic resonance (NMR) in zero and ultra-low magnetic field (ZULF, below 0.1 $\mu$T) where detection is based on a low-cost, non-cryogenic, spin-exchange relaxation free (SERF) $^{87}$Rb atomic…

Zero and ultralow-field nuclear magnetic resonance (ZULF NMR) is an NMR modality where experiments are performed in fields at which spin-spin interactions within molecules and materials are stronger than Zeeman interactions. This typically…

Hyperpolarized nuclear spins in molecules exhibit high magnetization that is unachievable by classical polarization techniques, making them widely used as sensors in physics, chemistry, and medicine. The state of a hyperpolarized material,…

Chemical Physics · Physics 2024-12-31 James Eills , Morgan W. Mitchell , Irene Marco Rius , Michael C. D. Tayler

Nuclear spin hyperpolarization utilizing parahydrogen has the potential for broad applications in chemistry, biochemistry, and medicine. This review examines recent chemical and biochemical insights gained using parahydrogen-induced…

Signal reception of nuclear magnetic resonance (NMR) usually relies on electrical amplification of the electromotive force caused by nuclear induction. Here, we report up-conversion of a radio-frequency NMR signal to an optical regime using…

The sensitivity of NMR and MRI can be boosted via hyperpolarization of nuclear spins. However, current methods are costly, polarization is relatively low, or applicability is limited. Here, we report a new hyperpolarization method combining…

Nuclear magnetic resonance (NMR) spectroscopy is a widely used tool for chemical analysis and molecular structure identification. Because it typically relies on the weak magnetic fields produced by a small thermal nuclear spin polarization,…

Applied Physics · Physics 2020-06-11 Dominik B. Bucher , David R. Glenn , Hongkun Park , Mikhail D. Lukin , Ronald L. Walsworth

We report measurements of zero- to ultra-low-field nuclear magnetic resonance (ZULF NMR) signals at frequencies of a few hertz with a diamond-based magnetic sensor. The sensing diamond is a truncated pyramid with 0.18 mm height and a 0.5 mm…

Zero-field (ZF) nuclear magnetic resonance (NMR) spectroscopy probes scalar J-couplings between nuclei while dispensing with large homogeneous magnetic fields, enabling low-cost and geometrically flexible detection, including through…

Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) suffer from inherently low sensitivity due to the weak thermal polarization of nuclear spins. Parahydrogen-induced polarization (PHIP) offers a powerful route to enhance…

Instrumentation and Detectors · Physics 2025-10-28 Yenal Gökpek , Jan-Bernd Hövener , Andrey N. Pravdivtsev

Access to magnetic resonance imaging (MRI) remains severely limited in low- and middle-income countries, especially in sub-Saharan Africa, despite rising rates of non-communicable diseases. Low-field MRI presents an affordable, locally…

Although 19F has high potential to serve as a background-free molecular marker in bioimaging, the molar amount of marker substance is often too small to enable 19F MR imaging or 19F NMR spectroscopy with a sufficiently high signal-to-noise…

Chemical Physics · Physics 2022-05-24 Johannes Bernarding , Christian Bruns , Isabell Prediger , Markus Plaumann

In this review, we describe the potentialities offered by the nuclear magnetic resonance (NMR) technique to explore at a microscopic level new quantum states of condensed matter induced by high magnetic fields. We focus on experiments…

Strongly Correlated Electrons · Physics 2017-11-30 Claude Berthier , Mladen Horvatić , Marc-Henri Julien , Hadrien Mayaffre , Steffen Krämer

We introduce a novel NMR approach that extends the capabilities of indirect dynamic nuclear polarization (DNP) under magic-angle spinning to probe the local environment of half-integer spin quadrupolar nuclei. Compared to…

We demonstrate ionization of a molecule with the bias voltage of a Scanning Tunnelling Microscope (STM) resulting in a coexistence of a neutral and ionic molecules, i.e. radical (paramagnetic) and non-radical (diamagnetic) states. This…

Mesoscale and Nanoscale Physics · Physics 2024-04-02 Yishay Manassen , Michael Averbukh , Zion Hazan , Yahel Tzuriel , Pino Boscolo , Alexsander Shnirman , Baruch Horovitz
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