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Despite its versatility and high chemical specificity, conventional NMR spectroscopy is limited in measurement throughput due to the need for high-homogeneity magnetic fields, necessitating sequential sample analysis, and bulky devices.…

Instrumentation and Detectors · Physics 2024-07-02 Blake Andrews , Matthew Lai , Zhen Wang , Norihisa Kato , Michael Tayler , Emanuel Druga , Ashok Ajoy

Ultralow-field nuclear magnetic resonance (NMR) provides a new regime for many applications ranging from materials science to fundamental physics. However, the experimentally observed spectra show asymmetric amplitudes, differing greatly…

Quantum Physics · Physics 2019-02-22 Min Jiang , Wenjie Xu , Yunlan Ji , Ji Bian , Shiming Song , Xinhua Peng

We report detection of nuclear magnetic resonance (NMR) using an anisotropic magnetoresistive (AMR) sensor. A ``remote-detection'' arrangement was used, in which protons in flowing water were pre-polarized in the field of a superconducting…

Chemical Physics · Physics 2015-05-13 F. Verpillat , M. P. Ledbetter , D. Budker , S. Xu , D. Michalak , C. Hilty , S. Antonijevic , A. Pines , L. -S. Bouchard

Zero- to ultra-low-field nuclear magnetic resonance (ZULF NMR) provides a new regime for the measurement of nuclear spin-spin interactions free from effects of large magnetic fields, such as truncation of terms that do not commute with the…

Magnetic sensors are important for detecting nuclear magnetization signals in nuclear magnetic resonance (NMR). As a complementary analysis tool to conventional high-field NMR, zero- and ultralow-field (ZULF) NMR detects nuclear…

Atomic Physics · Physics 2019-02-13 Min Jiang , Roman Picazo Frutos , Teng Wu , John W. Blanchard , Xinhua Peng , Dmitry Budker

Quantum sensors have attracted broad interest in the quest towards sub-micronscale NMR spectroscopy. Such sensors predominantly operate at low magnetic fields. Instead, however, for high resolution spectroscopy, the high-field regime is…

We investigate nuclear magnetic resonance (NMR) in near-zero-field, where the Zeeman interaction can be treated as a perturbation to the electron mediated scalar interaction (J-coupling). This is in stark contrast to the high field case,…

Modern experimental techniques can generate magnetic fields of the form H(t) = H0 z-hat + H1 [x-hat cos({\omega}t) + y-hat sin({\omega}t)], at frequencies within an order of magnitude of the nuclear magnetic resonance (NMR) and electron…

Atomic Physics · Physics 2026-02-19 Zhichen Liu , Richard A. Klemm

Nuclear magnetic resonance (NMR) spectroscopy provides unparalleled access to molecular structure and dynamics but is traditionally limited by weak signal strength, requiring large sample volumes and high magnetic fields. Here, we…

Applied Physics · Physics 2026-04-29 Dileep Singh , Riley W. Hooper , Christoph Findler , Utsab Banerjee , Dominik B. Bucher

An unusual regime for liquid-state nuclear magnetic resonance (NMR) where the magnetic field strength is so low that the $J$-coupling (intramolecular spin-spin) interactions dominate the spin Hamiltonian opens a new paradigm with…

Atomic Physics · Physics 2019-10-02 Dmitry Budker

Dynamic nuclear polarization (DNP) is an NMR sensitivity enhancement technique that mediates polarization transfer from unpaired electrons to NMR-active nuclei. Despite its success in elucidating important structural information on…

Scalar couplings of the form J I_1 \cdot I_2 between nuclei impart valuable information about molecular structure to nuclear magnetic-resonance spectra. Here we demonstrate direct detection of J-spectra due to both heteronuclear and…

Atomic Physics · Physics 2015-05-13 M. P. Ledbetter , C. W. Crawford , A. Pines , D. E. Wemmer , S. Knappe , J. Kitching , D. Budker

The drive to improve the sensitivity of nuclear magnetic resonance (NMR) to smaller and smaller sample volumes has led to the development of a variety of techniques distinct from conventional inductive detection. In this chapter, we focus…

Mesoscale and Nanoscale Physics · Physics 2021-10-26 M. Poggio , B. E. Herzog

Hyperpolarized nuclear magnetic resonance and lab-on-a-chip microfluidics are two dynamic, but until recently quite distinct, fields of research. Recent developments in both areas increased their synergistic overlap. By microfluidic…

Chemical Physics · Physics 2021-09-29 James Eills , William Hale , Marcel Utz

The antiferromagnetic manganite Pr$_{0.5}$Sr$_{0.5}$MnO$_3$ was investigated at low temperature by means of magnetometry and $^{55}$Mn NMR. A field-induced transition to a ferromagnetic state is detected by magnetization measurements at a…

Strongly Correlated Electrons · Physics 2009-10-31 G. Allodi , R. De Renzi , M. Solzi , K. Kamenev , G. Balakrishnan , M. W. Pieper

Characterization of the molecular properties of surfaces under ambient or chemically reactive conditions is a fundamental scientific challenge. Moreover, many traditional analytical techniques used for probing surfaces often lack dynamic or…

The NMR spectra of paramagnetic substances can feature shifts over thousands of ppm. In high magnetic field instruments, this corresponds to extreme offsets, which make it challenging or impossible to achieve uniform excitation without…

Chemical Physics · Physics 2021-11-08 Enrico Ravera

Dynamic nuclear polarization is widely used to enhance the sensitivity of nuclear magnetic resonance. It is presently the method of choice for enhancing the sensitivity of high-field solid state NMR experiments performed under cryogenic…

Chemical Physics · Physics 2022-02-02 Maria Grazia Concilio , Ilya Kuprov , Lucio Frydman

Zero- to ultralow-field nuclear magnetic resonance (ZULF NMR) is a powerful version of NMR that allows studying molecules and their transformations in the regime dominated by intrinsic spin-spin interactions. While spin dynamics at zero…

We demonstrate an interface-sensitive NMR in a semiconducting nanostructure, where an NMR signal from the minute heterojunction region of a model heterojunction structure (In$_{0.48}$Ga$_{0.52}$P/GaAs) is detected by using nuclear…

Mesoscale and Nanoscale Physics · Physics 2017-12-13 Atsushi Goto , Kenjiro Hashi , Shinobu Ohki , Tadashi Shimizu