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Time- and angle-resolved photoemission spectroscopy is a powerful technique for investigating the dynamics of excited carriers in quantum materials. Typically, data analysis proceeds via the inspection of time distribution curves (TDCs),…

Cryogenic electron microscopy (cryo-EM) provides images from different copies of the same biomolecule in arbitrary orientations. Here, we present an end-to-end unsupervised approach that learns individual particle orientations from cryo-EM…

Image and Video Processing · Electrical Eng. & Systems 2021-07-08 Youssef S. G. Nashed , Frederic Poitevin , Harshit Gupta , Geoffrey Woollard , Michael Kagan , Chuck Yoon , Daniel Ratner

Control over the physical properties of materials is ubiquitously required in many fields. One means by which this can be achieved is controlling the internal structure of multi-component materials with an eye to enhancing mechanical…

Soft Condensed Matter · Physics 2023-05-22 Rikuya Ishikawa , Marie Tani , Rei Kurita

Results: We present an application that enables the quantitative analysis of multichannel 5-D (x, y, z, t, channel) and large montage confocal fluorescence microscopy images. The image sequences show stem cells together with blood vessels,…

Diffusing wave spectroscopy (DWS) can be employed as an optical rheology tool with numerous applications for studying the structure, dynamics and linear viscoelastic properties of complex fluids, foams, glasses and gels. To carry out DWS…

Soft Condensed Matter · Physics 2018-11-06 Chi Zhang , Mathias Reufer , Danila Gaudino , Frank Scheffold

A profile from the Argo ocean observation array is a sequence of three-dimensional vectors composed of pressure, salinity, and temperature, appearing as a continuous curve in three-dimensional space. The shape of this curve is faithfully…

Geophysics · Physics 2020-09-15 Nozomi Sugiura , Shigeki Hosoda

The transport of bio-particles in viscous flows exhibits a rich variety of dynamical behaviour, such as morphological transitions, complex orientation dynamics or deformations. Characterising such complex behaviour under well controlled…

Complex spatial and temporal patterns of gene expression underlie embryo differentiation, yet methods do not yet exist for the efficient genome-wide determination of spatial expression patterns during development. In situ imaging of…

Genomics · Quantitative Biology 2013-08-15 Peter A. Combs , Michael B. Eisen

We report an accurate method to determine DNA barcodes from the dwell time measurement of protein tags (barcodes) along the DNA backbone using Brownian dynamics simulation of a model DNA and use a recursive theoretical scheme which improves…

Soft Condensed Matter · Physics 2021-02-09 Swarnadeep Seth , Aniket Bhattacharya

Dense object detection and temporal tracking are needed across applications domains ranging from people-tracking to analysis of satellite imagery over time. The detection and tracking of malignant skin cancers and benign moles poses a…

Computer Vision and Pattern Recognition · Computer Science 2016-12-06 Yunzhu Li , Andre Esteva , Brett Kuprel , Rob Novoa , Justin Ko , Sebastian Thrun

This paper describes an Artificial Embryology method (called ``Epigenetic Tracking'') to generate predefined arbitrarily shaped 2-dimensional arrays of cells by means of evolutionary techniques. It is based on a model of development, whose…

Adaptation and Self-Organizing Systems · Physics 2008-05-19 Alessandro Fontana

With the advance of experimental techniques such as time-lapse fluorescence microscopy, the availability of single-cell trajectory data has vastly increased, and so has the demand for computational methods suitable for parameter inference…

Quantitative Methods · Quantitative Biology 2016-07-06 Irena Kuzmanovska , Andreas Milias-Argeitis , Christoph Zechner , Mustafa Khammash

Accurately tracking particles and determining their coordinate along the optical axis is a major challenge in optical microscopy, especially when extremely high precision is needed. In this study, we introduce a deep learning approach using…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Andrey Alexandrov , Giovanni Acampora , Giovanni De Lellis , Antonia Di Crescenzo , Chiara Errico , Daria Morozova , Valeri Tioukov , Autilia Vittiello

We present a dual-stage neural network architecture for analyzing fine shape details from microscopy recordings in 3D. The system, tested on red blood cells, uses training data from both healthy donors and patients with a congenital blood…

Quantitative Methods · Quantitative Biology 2020-05-29 G. Simionato , K. Hinkelmann , R. Chachanidze , P. Bianchi , E. Fermo , R. van Wijk , M. Leonetti , C. Wagner , L. Kaestner , S. Quint

Gene expression analysis aims at identifying the genes able to accurately predict biological parameters like, for example, disease subtyping or progression. While accurate prediction can be achieved by means of many different techniques,…

Methodology · Statistics 2008-09-11 Christine De Mol , Sofia Mosci , Magali Traskine , Alessandro Verri

Tracking the coupled motion of electrons and nuclei on their intrinsic timescales is essential to understanding and controlling photochemical transformations. While attosecond techniques have provided unprecedented insight into electronic…

Guided upsampling is an effective approach for accelerating high-resolution image processing. In this paper, we propose a simple yet effective guided upsampling method. Each pixel in the high-resolution image is represented as a linear…

Computer Vision and Pattern Recognition · Computer Science 2023-07-20 Shuangbing Song , Fan Zhong , Tianju Wang , Xueying Qin , Changhe Tu

Single-cell trajectory analysis aims to reconstruct the biological developmental processes of cells as they evolve over time, leveraging temporal correlations in gene expression. During cellular development, gene expression patterns…

Applications · Statistics 2026-03-30 Junhao Zhu , Kevin Zhang , Zhaolei Zhang , Dehan Kong

In this work we introduce an Autoencoder for molecular conformations. Our proposed model converts the discrete spatial arrangements of atoms in a given molecular graph (conformation) into and from a continuous fixed-sized latent…

Machine Learning · Computer Science 2021-01-06 Robin Winter , Frank Noé , Djork-Arné Clevert

The goal of quantum tracking control is to identify shaped fields to steer observable expectation values along designated time-dependent tracks. The fields are determined via an iteration-free procedure, which is based on inverting the…

Quantum Physics · Physics 2024-02-06 Alicia B. Magann , Tak-San Ho , Christian Arenz , Herschel A. Rabitz
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