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We propose a dissipative electro-elastic network model (DENM) to describe the dynamics and statistics of electrostatic fluctuations at active sites of proteins. The model combines the harmonic network of residue beads with overdamped…

Biological Physics · Physics 2015-06-03 Daniel R. Martin , S. Banu Ozkan , Dmitry V. Matyushov

An important open problem in materials science is whether a direct connection exists between single-particle elastic properties and the macroscopic bulk behavior. Here we address this question by focusing on the archetype of soft colloids:…

Soft Condensed Matter · Physics 2019-09-11 Lorenzo Rovigatti , Nicoletta Gnan , Andrea Ninarello , Emanuela Zaccarelli

Simplified stochastic models are widely used in the study of frequency-resolved noise propagation in biochemical reaction networks, a common measure being the coherence between random fluctuations in molecule number trajectories. Such…

Molecular Networks · Quantitative Biology 2025-11-03 Juan David Marmolejo Lozano , Nikola Popovic , Ramon Grima

Models for cross-sectional network data have become increasingly well-developed in recent decades, and are widely used. This has led to a growing interest in the connection between such cross-sectional models and the behavioral processes…

Social and Information Networks · Computer Science 2026-05-05 Carter T. Butts , Alexander Murray-Watters

Prestrained elastic networks arise in a number of biological and technological systems ranging from the cytoskeleton of cells to tensegrity structures. To understand the response of such a network as a function of the prestrain, we consider…

Statistical Mechanics · Physics 2022-07-13 Ihusan Adam , Franco Bagnoli , Duccio Fanelli , L. Mahadevan , Paolo Paoletti

Networks of elastic fibers are ubiquitous in biological systems and often provide mechanical stability to cells and tissues. Fiber reinforced materials are also common in technology. An important characteristic of such materials is their…

The heterogeneous micromechanical properties of biological tissues have profound implications across diverse medical and engineering domains. However, identifying full-field heterogeneous elastic properties of soft materials using…

Numerical Analysis · Mathematics 2025-07-09 Wensi Wu , Mitchell Daneker , Kevin T. Turner , Matthew A. Jolley , Lu Lu

Elastic network models (ENM) and constraint-based, topological rigidity analysis are two distinct, coarse-grained approaches to study conformational flexibility of macromolecules. In the two decades since their introduction, both have…

Biomolecules · Quantitative Biology 2018-02-27 Dominik Budday , Sigrid Leyendecker , Henry van den Bedem

Elastic network models, simple structure-based representations of biomolecules where atoms interact via short-range harmonic potentials, provide great insight into a molecule's internal dynamics and mechanical properties at extremely low…

Soft Condensed Matter · Physics 2018-12-12 Patrick Diggins , Changjiang Liu , Markus Deserno , Raffaello Potestio

Athermal models of disordered fibrous networks are highly useful for studying the mechanics of elastic networks composed of stiff biopolymers. The underlying network architecture is a key aspect that can affect the elastic properties of…

Soft Condensed Matter · Physics 2016-01-20 Albert James Licup , Abhinav Sharma , Fred C. MacKintosh

A widely-studied model for gels or biopolymeric fibrous materials are networks with central force interactions, such as Hookean springs. Less commonly studied are materials whose mechanics are dominated by non-central force interactions…

Soft Condensed Matter · Physics 2019-09-02 Robbie Rens , Edan Lerner

The co-authorship network of scientists represents a prototype of complex evolving networks. By mapping the electronic database containing all relevant journals in mathematics and neuro-science for an eight-year period (1991-98), we infer…

Soft Condensed Matter · Physics 2009-11-07 A. L. Barabasi , H. Jeong , Z. Neda , E. Ravasz , A. Schubert , T. Vicsek

This study presents a Eulerian theory to elucidate the molecular kinematics in polymer networks and their connection to continuum deformation, grounded in fundamental statistical physics and thermodynamics. Three key innovations are…

Soft Condensed Matter · Physics 2025-07-16 Siyu Wang , Heng Xiao , Lin Zhan

We study the elastic behaviour of a supercoiled DNA molecule. The simplest model is that of a rod like chain, involving two elastic constants, the bending and the twist rigidities. We show that this model is singular and needs a small…

Condensed Matter · Physics 2009-10-31 Claude Bouchiat , Marc Mezard

A general expression for the elastic potential energy of a helical spring is derived using the basic concepts of elasticity theory and geometry. Both the translational and the rotational displacement of the spring's moving ends are…

Classical Physics · Physics 2025-11-24 Saša Ilijić , Ana Babić , Dora Ivrlač , Andrew DeBenedictis

Understanding crystal growth over arbitrary curved surfaces with arbitrary boundaries is a formidable challenge, stemming from the complexity of formulating non-linear elasticity using geometric invariant quantities. Solutions are generally…

Soft Condensed Matter · Physics 2025-01-22 Yankang Liu , Siyu Li , Roya Zandi , Alex Travesset

In this work, the mechanical response oF an one-dimensional active solid -- defined as a network of active stochastic particles interacting by nonlinear hard springs -- subject to an external deformation force, is numerically studied and…

Soft Condensed Matter · Physics 2022-09-28 Mario Sandoval

Despite the enormous success of artificial neural networks (ANNs) in many disciplines, the characterization of their computations and the origin of key properties such as generalization and robustness remain open questions. Recent…

Computer Vision and Pattern Recognition · Computer Science 2022-03-18 Nikos Karantzas , Emma Besier , Josue Ortega Caro , Xaq Pitkow , Andreas S. Tolias , Ankit B. Patel , Fabio Anselmi

We construct small-world spring networks based on a one dimensional chain and study its static and quasistatic behavior with respect to external forces. Regular bonds and shortcuts are assigned linear springs of constant $k$ and $k'$,…

Disordered Systems and Neural Networks · Physics 2009-11-11 A. Ramezanpour , S. M. Vaez Allaei

We focus at the interface between multiscale computations, bifurcation theory and social networks. In particular we address how the Equation-Free approach, a recently developed computational framework, can be exploited to systematically…

Computational Physics · Physics 2015-05-13 A. C. Tsoumanis , C. I. Siettos , I. G. Kevrekidis , G. V. Bafas