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The human brain exhibits a complex structure made of scale-free highly connected modules loosely interconnected by weaker links to form a small-world network. These features appear in healthy patients whereas neurological diseases often…

Neurons and Cognition · Quantitative Biology 2014-03-26 Roberta Russo , Hans J Herrmann , Lucilla de Arcangelis

The deterministic dynamics of randomly connected neural networks are studied, where a state of binary neurons evolves according to a discreet-time synchronous update rule. We give a theoretical support that the overlap of systems' states…

Statistical Mechanics · Physics 2015-03-10 Taro Toyoizumi , Haiping Huang

Entrainment of randomly coupled oscillator networks by periodic external forcing applied to a subset of elements is numerically and analytically investigated. For a large class of interaction functions, we find that the entrainment window…

Disordered Systems and Neural Networks · Physics 2015-06-25 Hiroshi Kori , Alexander S. Mikhailov

Networks describing the interaction of the elements that constitute a complex system grow and develop via a number of different mechanisms, such as the addition and deletion of nodes, the addition and deletion of edges, as well as the…

Molecular Networks · Quantitative Biology 2010-06-09 Arend Hintze , Christoph Adami

Modularity has been widely studied as a mechanism to improve the capabilities of neural networks through various techniques such as hand-crafted modular architectures and automatic approaches. While these methods have sometimes shown…

Neural and Evolutionary Computing · Computer Science 2024-10-28 Humphrey Munn , Marcus Gallagher

This paper investigates questions related to the modularity in discrete models of biological interaction networks. We develop a theoretical framework based on the analysis of their asymptotic dynamics. More precisely, we exhibit formal…

Discrete Mathematics · Computer Science 2012-01-16 Franck Delaplace , Hanna Klaudel , Tarek Melliti , Sylvain Sené

In this review, we discuss modularity and hierarchy in biological systems. We review examples from protein structure, genetics, and biological networks of modular partitioning of the geometry of biological space. We review theories to…

Populations and Evolution · Quantitative Biology 2015-06-04 Dirk M. Lorenz , Alice Jeng , Michael W. Deem

Efficient complex systems have a modular structure, but modularity does not guarantee robustness, because efficiency also requires an ingenious interplay of the interacting modular components. The human brain is the elemental paradigm of an…

Neurons and Cognition · Quantitative Biology 2022-06-08 Flaviano Morone , Kevin Roth , Byungjoon Min , H. Eugene Stanley , Hernán A. Makse

Attractor dynamics are a hallmark of many complex systems, including the brain. Understanding how such self-organizing dynamics emerge from first principles is crucial for advancing our understanding of neuronal computations and the design…

Neurons and Cognition · Quantitative Biology 2026-05-22 Tamas Spisak , Karl Friston

It has long been believed that the brain is highly modular both in terms of structure and function, although recent evidence has led some to question the extent of both types of modularity. We used artificial neural networks to test the…

Neurons and Cognition · Quantitative Biology 2024-10-15 Gabriel Béna , Dan F. M. Goodman

Hierarchical organization -- the recursive composition of sub-modules -- is ubiquitous in biological networks, including neural, metabolic, ecological, and genetic regulatory networks, and in human-made systems, such as large organizations…

Neural and Evolutionary Computing · Computer Science 2016-09-28 Henok Mengistu , Joost Huizinga , Jean-Baptiste Mouret , Jeff Clune

[Background] Several studies have mentioned network modularity -- that a network can easily be decomposed into subgraphs that are densely connected within and weakly connected between each other -- as a factor affecting metabolic…

Molecular Networks · Quantitative Biology 2012-10-10 Petter Holme

The relationship between network topology and system dynamics has significant implications for unifying our understanding of the interplay among metabolic, gene-regulatory, and ecosystem network architecures. Here we analyze the stability…

Populations and Evolution · Quantitative Biology 2015-06-17 Cameron Smith , Raymond S. Puzio , Aviv Bergman

The organization in brain networks shows highly modular features with weak inter-modular interaction. The topology of the networks involves emergence of modules and sub-modules at different levels of constitution governed by fractal laws.…

Neurons and Cognition · Quantitative Biology 2015-09-22 Soibam Shyamchand Singh , Khundrakpam Budhachandra Singh , Romana Ishrat , B. Indrajit Sharma , R. K. Brojen Singh

Modularity is a general principle present in many fields. It offers attractive advantages, including, among others, ease of conceptualization, interpretability, scalability, module combinability, and module reusability. The deep learning…

Machine Learning · Computer Science 2023-10-03 Haozhe Sun , Isabelle Guyon

Inspired from human cognition, machine learning systems are gradually revealing advantages of sparser and more modular architectures. Recent work demonstrates that not only do some modular architectures generalize well, but they also lead…

Machine Learning · Computer Science 2022-06-07 Sarthak Mittal , Yoshua Bengio , Guillaume Lajoie

The principle of self-organization has acquired a fundamental significance in the newly emerging field of computational philosophy. Self-organizing systems have been described in various domains in science and philosophy including physics,…

Neurons and Cognition · Quantitative Biology 2020-11-12 Birgitta Dresp-Langley

We investigate the role of connection density in an adaptive network model of chaotic units that dynamically rewire based on their internal states and local coherence. By systematically varying the network's connectivity density, we uncover…

Adaptation and Self-Organizing Systems · Physics 2025-08-19 Ramiro Plüss , Pablo Martín Gleiser

It has been hypothesized that some form of "modular" structure in artificial neural networks should be useful for learning, compositionality, and generalization. However, defining and quantifying modularity remains an open problem. We cast…

Machine Learning · Computer Science 2022-06-23 Richard D. Lange , David S. Rolnick , Konrad P. Kording

A central biological question is how natural organisms are so evolvable (capable of quickly adapting to new environments). A key driver of evolvability is the widespread modularity of biological networks--their organization as functional,…

Populations and Evolution · Quantitative Biology 2015-03-13 Jeff Clune , Jean-Baptiste Mouret , Hod Lipson