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Selection, mutation and random drift affect the dynamics of allele frequencies and consequently of quantitative traits. While the macroscopic dynamics of quantitative traits can be measured, the underlying allele frequencies are typically…

Populations and Evolution · Quantitative Biology 2016-03-15 Katarína Boďová , Gašper Tkačik , Nicholas H. Barton

We consider a single genetic locus which carries two alleles, labelled P and Q. This locus experiences selection and mutation. It is linked to a second neutral locus with recombination rate r. If r=0, this reduces to the study of a single…

Probability · Mathematics 2007-05-23 N. H. Barton , A. M. Etheridge , A. K. Sturm

We consider an infinitely large population under stabilising selection and mutation in which the allelic effects determining a polygenic trait vary between loci. We obtain analytical expressions for the stationary genetic variance as a…

Populations and Evolution · Quantitative Biology 2016-01-13 Kavita Jain , Wolfgang Stephan

The evolution of dispersal is a classical question in evolutionary ecology, which has been widely studied with several mathematical models. The main question is to define the fittest dispersal rate for a population in a bounded domain, and,…

Analysis of PDEs · Mathematics 2016-02-26 Benoit Perthame , Panagiotis E. Souganidis

We study the large population limit of the Moran process, assuming weak-selection, and for different scalings. Depending on the particular choice of scalings, we obtain a continuous model that may highlight the genetic-drift (neutral…

Populations and Evolution · Quantitative Biology 2013-01-21 Fabio A. C. C. Chalub , Max O. Souza

The Moran process is a foundational model of genetic drift and mutation in finite populations. In its standard two-allele form with population size $n$, allele counts, and hence allele frequencies, change through stochastic replacement and…

Populations and Evolution · Quantitative Biology 2026-01-16 Dan Braha , Marcus A. M. de Aguiar

We are interested in modelling Darwinian evolution, resulting from the interplay of phenotypic variation and natural selection through ecological interactions. Our models are rooted in the microscopic, stochastic description of a population…

Probability · Mathematics 2016-08-16 Nicolas Champagnat , Régis Ferrière , Sylvie Méléard

In large populations, multiple beneficial mutations may be simultaneously spreading. In asexual populations, these mutations must either arise on the same background or compete against each other. In sexual populations, recombination can…

Populations and Evolution · Quantitative Biology 2013-12-19 D. B. Weissman , O. Hallatschek

We study the evolution of allele frequencies in a large population where random mating is violated in a particular way that is related to recent works on speciation. Specifically, we consider non-random encounters in haploid organisms…

Populations and Evolution · Quantitative Biology 2013-09-05 David M. Schneider , Ayana B. Martins , Eduardo do Carmo , Marcus A. M. de Aguiar

We consider a Moran model with two allelic types, mutation and selection. In this work, we study the behaviour of the proportion of fit individuals when the size of the population tends to infinity, without any rescaling of parameters or…

Probability · Mathematics 2018-04-05 Fernando Cordero

We study ancestral structures for the two-type Moran model with mutation and frequency-dependent selection under the nonlinear dominance or fittest-type-wins scheme. Under appropriate conditions, both lead, in distribution, to the same…

Probability · Mathematics 2024-07-12 Ellen Baake , Luigi Esercito , Sebastian Hummel

We revisit the classical population genetics model of a population evolving under multiplicative selection, mutation and drift. The number of beneficial alleles in a multi-locus system can be considered a trait under exponential selection.…

adap-org · Physics 2007-05-23 Magnus Rattray , Jonathan L. Shapiro

The evolution of the allelic proportion $x$ of a biallelic locus subject to the forces of mutation and drift is investigated in a diffusion model, assuming small scaled mutation rates. The overall scaled mutation rate is parametrized with…

Populations and Evolution · Quantitative Biology 2014-09-09 Claus Vogl

In many models of genotypic evolution, the vector of genotype populations satisfies a system of linear ordinary differential equations. This system of equations models a competition between differential replication rates (fitness) and…

Populations and Evolution · Quantitative Biology 2009-11-13 Charles L. Epstein

We consider the evolution of populations under the joint action of mutation and differential reproduction, or selection. The population is modelled as a finite-type Markov branching process in continuous time, and the associated…

Populations and Evolution · Quantitative Biology 2009-02-23 Ellen Baake , Hans-Otto Georgii

We consider two versions of stochastic population models with mutation and selection. The first approach relies on a multitype branching process; here, individuals reproduce and change type (i.e., mutate) independently of each other,…

Populations and Evolution · Quantitative Biology 2009-02-19 E. Baake , R. Bialowons

We study a class of evolution models, where the breeding process involves an arbitrary exchangeable process, allowing for mutations to appear. The population size $n$ is fixed, hence after breeding, selection is applied. Individuals are…

Probability · Mathematics 2022-05-03 Daniela Bertacchi , Juri Lember , Fabio Zucca

We consider a integro-differential nonlinear model that describes the evolution of a population structured by a quantitative trait. The interactions between traits occur from competition for resources whose concentrations depend on the…

Analysis of PDEs · Mathematics 2011-12-05 Nicolas Champagnat , Pierre-Emmanuel Jabin

We are interested in modeling Darwinian evolution resulting from the interplay of phenotypic variation and natural selection through ecological interactions. The population is modeled as a stochastic point process whose generator captures…

Probability · Mathematics 2011-02-01 Benjamin Jourdain , Sylvie Méléard , Wojbor Woyczynski

We consider the Moran model of population genetics with two types, mutation, and selection, and investigate the line of descent of a randomly-sampled individual from a contemporary population. We trace this ancestral line back into the…

Probability · Mathematics 2024-05-22 Ellen Baake , Enrico Di Gaspero , Fernando Cordero
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