English
Related papers

Related papers: GSGS: A Computational Framework to Reconstruct Sig…

200 papers

Genetic interaction measures how different genes collectively contribute to a phenotype, and can reveal functional compensation and buffering between pathways under genetic perturbations. Recently, genome-wide screening for genetic…

Molecular Networks · Quantitative Biology 2015-03-17 Gang Fang , Wen Wang , Vanja Paunic , Benjamin Oately , Majda Haznadar , Michael Steinbach , Brian Van Ness , Chad L. Myers , Vipin Kumar

Knowledge graphs (KGs) store enormous facts as relationships between entities. Due to the long-tailed distribution of relations and the incompleteness of KGs, there is growing interest in few-shot knowledge graph completion (FKGC). Existing…

Information Retrieval · Computer Science 2024-08-06 Zicheng Zhao , Linhao Luo , Shirui Pan , Chengqi Zhang , Chen Gong

We present a theoretically grounded Gaussian process framework that leverages neural feature maps to construct expressive kernels. We show that the learned feature map can be interpreted as an optimal low-rank approximation to a Gram matrix…

Machine Learning · Statistics 2026-05-12 Anthony Stephenson

In this work, we developed a network inference method from incomplete data ("PathInf") , as massive and non-uniformly distributed missing values is a common challenge in practical problems. PathInf is a two-stages inference model. In the…

Machine Learning · Statistics 2018-10-02 Xiang Li , Qitian Chen , Xing Wang , Ning Guo , Nan Wu , Quanzheng Li

This paper considers the problem of interpolating signals defined on graphs. A major presumption considered by many previous approaches to this problem has been lowpass/ band-limitedness of the underlying graph signal. However, inspired by…

Information Theory · Computer Science 2017-05-09 Mahdi Boloursaz Mashhadi , Maryam Fallah , Farokh Marvasti

With the recent advent of high-throughput genotyping techniques, genetic data for genome-wide association studies (GWAS) have become increasingly available, which entails the development of efficient and effective statistical approaches.…

Applications · Statistics 2015-02-04 Jiahan Li , Wei Zhong , Runze Li , Rongling Wu

In this paper, we consider the problem of subsampling and reconstruction of signals that reside on the vertices of a product graph, such as sensor network time series, genomic signals, or product ratings in a social network. Specifically,…

Signal Processing · Electrical Eng. & Systems 2018-07-03 Guillermo Ortiz-Jiménez , Mario Coutino , Sundeep Prabhakar Chepuri , Geert Leus

Introduction The focus of analyzing data from microarray experiments and extracting biological insight from such data has experienced a shift from identification of individual genes in association with a phenotype to that of biological…

Genomics · Quantitative Biology 2015-08-10 Lei Zhang , Linlin Wang , Pu Tian , Suyan Tian

A well-known pitfall of molecular generative models is that they are not guaranteed to generate synthesizable molecules. Existing solutions for this problem often struggle to effectively navigate exponentially large combinatorial space of…

Machine Learning · Computer Science 2026-01-13 Seul Lee , Karsten Kreis , Srimukh Prasad Veccham , Meng Liu , Danny Reidenbach , Saee Paliwal , Weili Nie , Arash Vahdat

Inferring dependence structure through undirected graphs is crucial for uncovering the major modes of multivariate interaction among high-dimensional genomic markers that are potentially associated with cancer. Traditionally, conditional…

Methodology · Statistics 2016-04-04 Anindya Bhadra , Arvind Rao , Veerabhadran Baladandayuthapani

Graph neural networks (GNNs) have emerged as powerful tools for learning protein structures by capturing spatial relationships at the residue level. However, existing GNN-based methods often face challenges in learning multiscale…

Machine Learning · Computer Science 2026-02-03 Shih-Hsin Wang , Yuhao Huang , Taos Transue , Justin Baker , Jonathan Forstater , Thomas Strohmer , Bao Wang

Inferring Gene Regulatory Networks (GRNs) from gene expression data is crucial for understanding biological processes. While supervised models are reported to achieve high performance for this task, they rely on costly ground truth (GT)…

Machine Learning · Statistics 2025-06-10 Tianyu Cui , Song-Jun Xu , Artem Moskalev , Shuwei Li , Tommaso Mansi , Mangal Prakash , Rui Liao

Motivation: Measurements of gene expression over time enable the reconstruction of transcriptional networks. However, Bayesian networks and many other current reconstruction methods rely on assumptions that conflict with the differential…

Molecular Networks · Quantitative Biology 2009-07-02 D. R. Bickel , Z. Montazeri , P. -C. Hsieh , M. Beatty , S. J. Lawit , N. J. Bate

We derive a novel generative model from iterative Gaussian posterior inference. By treating the generated sample as an unknown variable, we can formulate the sampling process in the language of Bayesian probability. Our model uses a…

Machine Learning · Computer Science 2026-01-28 Marten Lienen , Marcel Kollovieh , Stephan Günnemann

Scene graphs provide a rich, structured representation of a scene by encoding the entities (objects) and their spatial relationships in a graphical format. This representation has proven useful in several tasks, such as question answering,…

Computer Vision and Pattern Recognition · Computer Science 2022-12-01 Sanjoy Kundu , Sathyanarayanan N. Aakur

Explicit neural representations such as 3D Gaussian Splatting (3DGS) enable high-fidelity and real-time novel view synthesis, yet optimize for alpha-composited optical appearance rather than ray-intersectable geometry. In contrast,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Niklas Vaara , Lam Huynh , Pekka Sangi , Miguel Bordallo López , Janne Heikkilä

Transmissive scenes are ubiquitous in daily life, yet reconstructing and rendering them remains highly challenging due to the inherent entanglement between near-field reflections from the surrounding environment on the transmissive surface,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Zhenyu Liang , Xiao Zhang , Tianchao Li , Jack C. P. Cheng , Chi-Keung Tang

How do mammalian cells that share the same genome exist in notably distinct phenotypes, exhibiting differences in morphology, gene expression patterns, and epigenetic chromatin statuses? Furthermore how do cells of different phenotypes…

Molecular Networks · Quantitative Biology 2014-04-29 Ping Wang , Chaoming Song , Hang Zhang , Zhanghan Wu , Jianhua Xing

In standard genetic programming (stdGP), solutions are varied by modifying their syntax, with uncertain effects on their semantics. Geometric-semantic genetic programming (GSGP), a popular variant of GP, effectively searches the semantic…

Neural and Evolutionary Computing · Computer Science 2025-01-31 Philipp Anthes , Dominik Sobania , Franz Rothlauf

While generative modeling has become prevalent across numerous research fields, its integration into the realm of image retrieval remains largely unexplored and underjustified. In this paper, we present a novel methodology, reframing image…

Computer Vision and Pattern Recognition · Computer Science 2024-07-25 Yidan Zhang , Ting Zhang , Dong Chen , Yujing Wang , Qi Chen , Xing Xie , Hao Sun , Weiwei Deng , Qi Zhang , Fan Yang , Mao Yang , Qingmin Liao , Jingdong Wang , Baining Guo