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Iterative refinement methods based on a denoising-inversion cycle are powerful tools for enhancing the quality and control of diffusion models. However, their effectiveness is critically limited when combined with standard Classifier-Free…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Haosen Li , Wenshuo Chen , Shaofeng Liang , Lei Wang , Haozhe Jia , Yutao Yue

We propose a representation of Gaussian processes (GPs) based on powers of the integral operator defined by a kernel function, we call these stochastic processes integral Gaussian processes (IGPs). Sample paths from IGPs are functions…

Machine Learning · Statistics 2019-03-08 Zilong Tan , Sayan Mukherjee

Reconstructing complete and interactive 3D scenes remains a fundamental challenge in computer vision and robotics, particularly due to persistent object occlusions and limited sensor coverage. Multiview observations from a single scene scan…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Wenhao Hu , Zesheng Li , Haonan Zhou , Liu Liu , Xuexiang Wen , Zhizhong Su , Xi Li , Gaoang Wang

Retrosynthesis prediction is one of the fundamental challenges in organic chemistry and related fields. The goal is to find reactants molecules that can synthesize product molecules. To solve this task, we propose a new graph-to-graph…

Quantitative Methods · Quantitative Biology 2022-04-20 Zaiyun Lin , Shiqiu Yin , Lei Shi , Wenbiao Zhou , YingSheng Zhang

Relational databases are extensively utilized in a variety of modern information system applications, and they always carry valuable data patterns. There are a huge number of data mining or machine learning tasks conducted on relational…

Machine Learning · Computer Science 2023-12-05 Han Zhang , Quan Gan , David Wipf , Weinan Zhang

A central task in many applications is reasoning about processes that change over continuous time. Continuous-Time Bayesian Networks is a general compact representation language for multi-component continuous-time processes. However, exact…

Artificial Intelligence · Computer Science 2012-06-18 Tal El-Hay , Nir Friedman , Raz Kupferman

Genomic signal processing has been used successfully in bioinformatics to analyze biomolecular sequences and gain varied insights into DNA structure, gene organization, protein binding, sequence evolution, etc. But challenges remain in…

Genomics · Quantitative Biology 2022-11-04 Saish Jaiswal , Shreya Nema , Hema A Murthy , Manikandan Narayanan

The recent development of high-throughput sequencing creates a large collection of multi-omics data, which enables researchers to better investigate cancer molecular profiles and cancer taxonomy based on molecular subtypes. Integrating…

Genomics · Quantitative Biology 2024-01-25 Bingjun Li , Sheida Nabavi

Guided source separation (GSS) is a type of target-speaker extraction method that relies on pre-computed speaker activities and blind source separation to perform front-end enhancement of overlapped speech signals. It was first proposed…

Audio and Speech Processing · Electrical Eng. & Systems 2023-08-15 Desh Raj , Daniel Povey , Sanjeev Khudanpur

Sampling of signals belonging to a low-dimensional subspace has well-documented merits for dimensionality reduction, limited memory storage, and online processing of streaming network data. When the subspace is known, these signals can be…

Information Theory · Computer Science 2019-11-26 Fernando Gama , Antonio G. Marques , Gonzalo Mateos , Alejandro Ribeiro

Stratifying cancer patients based on their gene expression levels allows improving diagnosis, survival analysis and treatment planning. However, such data is extremely highly dimensional as it contains expression values for over 20000 genes…

This paper presents a new modeling strategy for joint unsupervised analysis of multiple high-throughput biological studies. As in Multi-study Factor Analysis, our goals are to identify both common factors shared across studies and…

Applications · Statistics 2018-06-27 Roberta De Vito , Ruggero Bellio , Lorenzo Trippa , Giovanni Parmigiani

We present a novel computational approach for extracting weak signals, whose exact location and width may be unknown, from complex background distributions with an arbitrary functional form. We focus on datasets that can be naturally…

High Energy Physics - Experiment · Physics 2023-03-22 Abhijith Gandrakota , Amitabh Lath , Alexandre V. Morozov , Sindhu Murthy

We present GNN-Suite, a robust modular framework for constructing and benchmarking Graph Neural Network (GNN) architectures in computational biology. GNN-Suite standardises experimentation and reproducibility using the Nextflow workflow to…

Machine Learning · Computer Science 2025-05-19 Sebestyén Kamp , Giovanni Stracquadanio , T. Ian Simpson

A new algorithm is developed to tackle the issue of sampling non-Gaussian model parameter posterior probability distributions that arise from solutions to Bayesian inverse problems. The algorithm aims to mitigate some of the hurdles faced…

Machine Learning · Statistics 2019-11-19 Leen Alawieh , Jonathan Goodman , John B. Bell

Identifying structures in common forms the basis for networked systems design and optimization. However, real structures represented by graphs are often of varying sizes, leading to the low accuracy of traditional graph classification…

Machine Learning · Computer Science 2024-09-04 Xiaoyu Zhang , Wenchuan Yang , Jiawei Feng , Bitao Dai , Tianci Bu , Xin Lu

We present Generative Semantic Segmentation (GSS), a generative learning approach for semantic segmentation. Uniquely, we cast semantic segmentation as an image-conditioned mask generation problem. This is achieved by replacing the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-11 Jiaqi Chen , Jiachen Lu , Xiatian Zhu , Li Zhang

A genome-wide association study (GWAS) correlates marker variation with trait variation in a sample of individuals. Each study subject is genotyped at a multitude of SNPs (single nucleotide polymorphisms) spanning the genome. Here we assume…

Machine Learning · Statistics 2019-01-14 Kevin L. Keys , Gary K. Chen , Kenneth Lange

This paper aims to predict gene expression from a histology slide image precisely. Such a slide image has a large resolution and sparsely distributed textures. These obstruct extracting and interpreting discriminative features from the…

Computer Vision and Pattern Recognition · Computer Science 2022-11-01 Yan Yang , LiYuan Pan , Liu Liu , Eric A Stone

Multi-trait genome-wide association studies (GWAS) use multi-variate statistical methods to identify associations between genetic variants and multiple correlated traits simultaneously, and have higher statistical power than independent…

Genomics · Quantitative Biology 2022-02-10 Muhammad Ammar Malik , Adriaan-Alexander Ludl , Tom Michoel
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